DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nelf-A and nelfa

DIOPT Version :9

Sequence 1:	NP_001262804.1	Gene:	Nelf-A / 42520	FlyBaseID:	FBgn0038872	Length:	1264	Species:	Drosophila melanogaster
Sequence 2:	XP_002936807.1	Gene:	nelfa / 100135733	XenbaseID:	XB-GENE-988837	Length:	527	Species:	Xenopus tropicalis

Alignment Length:	557	Identity:	189/557 - (33%)
Similarity:	266/557 - (47%)	Gaps:	105/557 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MANVRDSDTSLWLHNKLGTSNDSWINGSICSQLNKEVLRNIKECFPDLQTQVKLKLLLSFLHIPR 65
            ||::|:|||.||||||||::::.|...||.|.|...|:.|::.||.:|.:.|||||||..||:||
Frog     1 MASMRESDTGLWLHNKLGSADELWAPPSIASLLTASVIDNVRLCFHNLSSAVKLKLLLGILHLPR 65

  Fly    66 RLVEEWKAELEEVIEVAGLDSELWVSMLAETMKTFPATSSLNTEISDYEDTRPIFIDMVNDLRKL 130
            |.|:|.|..|.|:|::|.|||:.|:.|:|:.:|:||.|.|||.   |.|:..|...|::.:||:.
Frog    66 RTVDEMKGALTEIIQLATLDSDPWILMVADILKSFPDTGSLNL---DLEEQNPNVQDILGELREK 127

  Fly   131 VTKHSDLGMLPLECQYLNKNALISVVGQQPAPVKHFTLKRKPKSAQLRTELLHKSADAQSSLKKA 195
            |::.....||||||||||||||.::.|....|||||.||||||||.||.|||.||.:....|||.
Frog   128 VSECEASAMLPLECQYLNKNALTTLAGPLTPPVKHFQLKRKPKSATLRAELLQKSTETAQQLKKT 192

  Fly   196 SAPTIPLRSRGMPRKMTDTTPLKGIPSRMPTTGFRSATVPGNAAQRPNLSRTPAG------RKDG 254
            :......:.||:.:|:..||||||||.:.|   |||.|.|  :...|..:|||..      ||:.
Frog   193 AGVPFHSKGRGLVKKLDTTTPLKGIPKQAP---FRSPTTP--SVFSPTANRTPIAPSRTPLRKER 252

  Fly   255 GIKLIEFTEQPL--GYAAAKKRKR--EQQLEEQQKKQEQKQQQ-----AAAAAAAAATAAASNAG 310
            |:||::.:|...  |...||||::  |.::.|:..|:|...:.     ||...:.....|.:|
Frog   253 GVKLLDISELDTVGGGREAKKRRKTVEAEVVEKPPKEETVLENPTPDYAAGLVSTQKLGALNN-- 315

  Fly   311 DSSPTDAATASGGETPVTPTSANNSFEIKMEPQQLNQSAGSLEEPQDDEMSGKANMECDIETPEY 375
                 ::|..|....|.||:...:|..|   |....|.||.:.|.
Frog   316 -----ESALPSTSYLPATPSVVPSSSYI---PTSEAQQAGPVREA-------------------- 352

  Fly   376 ATATLDFAQATSTSVADGQPGKP-AVETKLKT---PRTPKSAAKLNNNNNNNNNNSFNHTPKRIK 436
                   .|||.      ||.:| |..|.|.|   .|||.         .::|.|:...||.
Frog   353 -------LQATR------QPEEPTAANTTLPTQFKQRTPM---------YHSNPNAATTTPS--- 392

  Fly   437 QEIEIKSEEIIVPASIKLEKIETSPSTQRVSIQQQPPSLVQRTPHLLIRSSPQKRQNNGATTS-- 499
                        ||:     ..|||.|...:....|.:   :.|.:..::.||.::|...|..
Frog   393 ------------PAA-----TPTSPLTPAATQAATPAA---QAPQITTQTQPQPKKNLSLTREQM 437

  Fly   500 -AGTTTTTVGNTTIKMEKLDIKPMIRATGVSPSTSAG 535
             |........|...:.||..|...:..:..:|....|
Frog   438 YAAQEMFKTANKVTRPEKALILGFMAGSRENPCPEQG 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nelf-A	NP_001262804.1	None
nelfa	XP_002936807.1	Herpes_BLLF1	<269..>422	CDD:282904	49/227 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008325
OrthoInspector	1	1.000	-	-		oto104827
Panther	1	1.100	-	-	LDO	PTHR13328
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4683
SonicParanoid	1	1.000	-	-		X6309
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.040