DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3337 and ATPSCKMT

DIOPT Version :9

Sequence 1:	NP_001303427.1	Gene:	CG3337 / 42519	FlyBaseID:	FBgn0038871	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_954584.2	Gene:	ATPSCKMT / 134145	HGNCID:	27029	Length:	233	Species:	Homo sapiens

Alignment Length:	191	Identity:	90/191 - (47%)
Similarity:	114/191 - (59%)	Gaps:	9/191 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 NPLAKTPKSGMSTGGKILIAATGGVGIGLSIVCASFVAPAFRRICLPYVPATTEQIQNVLSFLPK 74
            |.|.|      |..|.:|....||..:.:..|...||.||.|::|||:|||||:||:||:..| :
Human    29 NSLQK------SNWGFLLTGLVGGTLVAVYAVATPFVTPALRKVCLPFVPATTKQIENVVKML-R 86

  Fly    75 NSAGKLLDIGSGDGRIVVAAAQHCGALKADGVELNPWLVYYSRLAALRHSVSKRTRFFRRDLWKF 139
            ...|.|:||||||||||:|||:.  ...|.|.|||||||:|||..|.|..|....:|:..||||.
Human    87 CRRGSLVDIGSGDGRIVIAAAKK--GFTAVGYELNPWLVWYSRYRAWREGVHGSAKFYISDLWKV 149

  Fly   140 DIKDYNFVVIFGVEQMMQDLEHKLIAECPHNTKIIACRFPLPSLEHVKIIEDGVNTVWFYD 200
            ....|:.||||||.|||..||.||..|...:.::||||||.|......:..:|::|||.||
Human   150 TFSQYSNVVIFGVPQMMLQLEKKLERELEDDARVIACRFPFPHWTPDHVTGEGIDTVWAYD 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3337	NP_001303427.1	Methyltransf_18	78..167	CDD:289607	49/88 (56%)
ATPSCKMT	NP_954584.2	Required for mitochondrial location. /evidence=ECO:0000269\|PubMed:30530489	56..90		18/34 (53%)
ATPSCKMT	NP_954584.2	AdoMet_MTases	83..>188	CDD:388410	54/107 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147638
Domainoid	1	1.000	164	1.000	Domainoid score	I3937
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16780
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4193
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48183
OrthoDB	1	1.010	-	-		D1605787at2759
OrthoFinder	1	1.000	-	-		FOG0007117
OrthoInspector	1	1.000	-	-		oto89390
orthoMCL	1	0.900	-	-		OOG6_101641
Panther	1	1.100	-	-	LDO	PTHR13610
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4449
SonicParanoid	1	1.000	-	-		X5204
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800