Protein Alignment Oga and Oga

DIOPT Version :10

• Sequence 1: NP_650956.1
• Gene: Oga / 42518
• FlyBaseID: FBgn0038870
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001390278.1
• Gene: Oga / 76055
• MGIID: 1932139
• Length: 954
• Species: Mus musculus
• Alignment Length: 1030
• Identity: 374/1030 - (36%)
• Similarity: 560/1030 - (54%)
• Gaps: 190/1030 - (18%)

  Fly     9 ADGKRQFICGVIEGFYGRPWTTEQRKDLFRKLKSMGMGSSPSYMYAPKDDYKHRAYWRELYTVEE 73
            |.|.|:|:|||:||||||||..||||:|||:|:...:.   :|:||||||||||.:|||:|:|||
Mouse    92 AGGARRFLCGVVEGFYGRPWVMEQRKELFRRLQKWELN---TYLYAPKDDYKHRMFWREMYSVEE 153

  Fly    74 ADHLSSLIAAAKEAGITFYYALSPGLDMTYSSPKEIATLKRKLDQVAQFGCEAYALLFDDIESEL 138
            |:.|.:||:||:|..|.|.||:|||||:|:|:|||::|||||||||:||||.::|||||||:..:
Mouse   154 AEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKLDQVSQFGCRSFALLFDDIDHNM 218

  Fly   139 SKADKEVFQTFANAHVSVTNEIYTHLGSPR-FLFCPTQYCASRAVPTVQESEYLNTLGSKLNNEI 202
            ..||||||.:||:|.||:|||||.:||.|. ||||||:||.:...|.|.:|.||.|:|.||...|
Mouse   219 CAADKEVFSSFAHAQVSITNEIYQYLGEPETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGI 283

  Fly   203 DILWTGDKVISKNISLESIQEITEVLRRPPCIWDNLHANDYDQKRIFMGPYSGRSPELIPHLRGV 267
            ::||||.||:||.|.:|||:|::::::|.|.||||:|||||||||:|:|||.|||.||||.|:||
Mouse   284 EVLWTGPKVVSKEIPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLKGV 348

  Fly   268 MTNPNCEFYGNFVAIHSLAFWSRCSL----------DSKVNSSLSADIKLETE-NDDDLPAEFLS 321
            :|||||||..|:||||:||.|.:.::          ||: :|::|..||||.| :|:|:..:.|
Mouse   349 LTNPNCEFEANYVAIHTLATWYKSNMNGVRKDVVMTDSE-DSTVSIQIKLENEGSDEDIETDVL- 411

  Fly   322 KNVYHPRLALKNAITEWLPEFFMKKEAWGPITKPQPQVQMVMPIIPIIPSINTCMSLTTTTTTST 386
               |.|::|||.|:||||.||.:..:                     ..|.....|...|:....
Mouse   412 ---YSPQMALKLALTEWLQEFGVPHQ---------------------YSSRQVAHSGAKTSVVDG 452

  Fly   387 SSRTVPPTVNTTQLQALADVCVVTSSLTPISNPVMN---SLVSPTKVITNDDIINPIPTTAASNI 448
            :.....|::|.|        .|||   |....|:|:   :|.....|:|.::
Mouse   453 TPLVAAPSLNAT--------TVVT---TVYQEPIMSQGAALSGEPSVLTKEE------------- 493

  Fly   449 ELPKKIPISVVPVPIMETKSVEASVELALDNAVFDDNEIEPNSDSVKERLELEVNLEGKQEPVAN 513
              .||.| ...|:.::..|..||..:        :||:|.......|...||.
Mouse   494 --EKKQP-DEEPMDMVVEKQEEAEHK--------NDNQILTEIVEAKMAEELR------------ 535

  Fly   514 LSVDTMLDDDSLSPLSGVVNEPMECSSSITSQVSPREEEAIKVVADDVLMESVNDVHSMHVESGT 578
             .:||  |.:|:             :.|.:.::|.:|             :.:.||
Mouse   536 -PMDT--DKESM-------------AESKSPEMSMQE-------------DCIPDV--------- 562

  Fly   579 SSPISNAEMREETEAQSDR----TNDNNTIEGEGITVDDLVLLCDLFYLPFEHGSRGHKLLVEFN 639
                  |.|:.:.:.|.::    .|:......|.:|::||.||.||||||:|||.:|.::|.||.
Mouse   563 ------APMQTDEQTQKEQFVPGPNEKPLYTAEPVTLEDLQLLADLFYLPYEHGPKGAQMLREFQ 621

  Fly   640 WLKGNANVILQDRSAGGGGDAIKSDKPEVSEWHQRREQFDQLCSAVVELLIKIANCPNKEICHEL 704
            ||:.|::|:    |....|    .|..::.||..|..:|:::|:.|:.:..:::||.|:.|.:::
Mouse   622 WLRANSSVV----SVNCKG----KDSEKIEEWRSRAAKFEEMCALVMGMFTRLSNCANRTILYDM 678

  Fly   705 YSYMWDISGALSLLNCYVKWLALGHFPQNTSSYTEGSYTWFSKGWKEAFMSGDQEPWVFRGGLIA 769
            |||:|||...:|::..:|:||..    ::.||              ..|:.||||||.|||||..
Mouse   679 YSYVWDIKSIMSMVKSFVQWLGC----RSHSS--------------AQFLIGDQEPWAFRGGLAG 725

  Fly   770 DLQRLMPVDSGNDLFVYKLPEQPTANYYLLRPYCNSDEQQVNDLCTRLYLQWRGELDGGRHIPFP 834
            :.|||:|:|..||||....|..||:..|.:|||...||..|..:|..:|       |.|...||
Mouse   726 EFQRLLPIDGANDLFFQPPPLTPTSKVYTIRPYFPKDEASVYKICREMY-------DDGVGFPF- 782

  Fly   835 LPANVPNIVADGLIGGYLTLSPQLCIVAYDESNRIIGYSCAALDVNIFRRNLELCWYTELREKYS 899
              .:.|:::.|.|:||.|:||...|.|..||.. |.||:...:||..|.:..::.|...::|||:
Mouse   783 --QSQPDLIGDKLVGGLLSLSLDYCFVLEDEDG-ICGYALGTVDVTPFIKKCKISWIPFMQEKYT 844

  Fly   900 RDICPLEGGEEVVQLVTSLVESYHDSSGNGALDQCPVEVSGSFPAVLISGTLREAEERDSGITKR 964
            :     ..|::.:.....::.|:|:..     :..|.....:||:::.....::.  .|..:.|.
Mouse   845 K-----PNGDKELSEAEKIMLSFHEEQ-----EVLPETFLANFPSLIKMDIHKKV--TDPSVAKS 897

  Fly   965 MLTVLLAALRANGCFGAHVRVPQQDVAQVNFYSRIGFVDVYREEA--TKCIYMGR 1017
            |:..||::|:|||..||...|...|...:.|||::|..::.:.|.  ...:.:||
Mouse   898 MMACLLSSLKANGSRGAFCEVRPDDKRILEFYSKLGCFEIAKMEGFPKDVVILGR 952

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oga	NP_650956.1	NAGidase	17..292	CDD:429533	172/275 (63%)
		RimI	<960..1019	CDD:440224	19/60 (32%)
Oga	NP_001390278.1	NAGidase	100..376	CDD:429533	172/276 (62%)
		RimI	<894..954	CDD:440224	19/59 (32%)