Protein Alignment Oga and oga-1

DIOPT Version :10

• Sequence 1: NP_650956.1
• Gene: Oga / 42518
• FlyBaseID: FBgn0038870
• Length: 1019
• Species: Drosophila melanogaster
• Sequence 2: NP_001123184.1
• Gene: oga-1 / 181164
• WormBaseID: WBGene00020596
• Length: 872
• Species: Caenorhabditis elegans
• Alignment Length: 1041
• Identity: 279/1041 - (26%)
• Similarity: 466/1041 - (44%)
• Gaps: 261/1041 - (25%)

  Fly    14 QFICGVIEGFYGRPWTTEQRKDLFRKLKSMGMGSSPSYMYAPKDDYKHRAYWRELYTVEEADHLS 78
            ::||||:|||||||||.||||.||::...:|:   .:|:||||||.|||:.|||||..||..:|.
 Worm    17 KYICGVVEGFYGRPWTPEQRKHLFKRQNQLGL---TTYLYAPKDDIKHRSLWRELYNNEEMTYLR 78

  Fly    79 SLIAAAKEAGITFYYALSPGLDMTYSSPKEIATLKRKLDQVAQFGCEAYALLFDDIESELSKADK 143
            :|:.:||:..:.|.||:|||.|:.|||.:|:.|||.|||||...||:::|:||||||.::...|:
 Worm    79 NLVESAKDNNVNFVYAISPGKDILYSSDEEMDTLKNKLDQVRSVGCDSFAVLFDDIEVQMQDEDQ 143

  Fly   144 EVFQTFANAHVSVTNEIYTHLGSPRFLFCPTQYCASRAVPTVQESEYLNTLGSKLNNEIDILWTG 208
            :.|.:||:|.|.:.|.|:.:|.:..|:||||:||.||||||::.|:||||:|.:|..:|.|:|||
 Worm   144 KQFTSFAHAQVHIANTIFKYLNTKTFMFCPTEYCESRAVPTLESSQYLNTIGEQLAGDIHIMWTG 208

  Fly   209 DKVISKNISLESIQEITEVLRRPPCIWDNLHANDYDQKRIFMGPYSGRSPELIPHLRGVMTNPNC 273
            .:|||:.:::|.:..:..|:||.|.|||||||||||.|:|||||...||.::.....|:::|||.
 Worm   209 PRVISRYLTVEHLARVGSVMRRKPLIWDNLHANDYDLKKIFMGPMMHRSVKIKEFTSGLLSNPNG 273

  Fly   274 EFYGNFVAIHSLAFWSRCSLDSKVNSSLSADI--KLETENDDD---------LPAEFLSKNVYHP 327
            .:..|||..|:|:.|:....|.:.:....|.:  :::|.:|:.         |..:..::.:|.|
 Worm   274 RYEANFVPFHTLSDWNAADRDLRESECCEALLVARIKTTSDESGISSRNGVILNIDCNTETIYVP 338

  Fly   328 RLALKNAITEWLPEFFMKKEAWGPITK-PQPQVQMVMPIIPIIPSINTCMSLTTTTTTSTSSRTV 391
            .::|.||::.|:.||....     :|. |||. |:...:...:|....|:.|
 Worm   339 EVSLVNAVSTWIDEFITPS-----VTNAPQPP-QLTADVAGYVPDRRECVWL------------- 384

  Fly   392 PPTVNTTQLQALADVCVVTSSLTPISNPVMNSLVSPTKVITNDDIINPIPTTAASNIELPKKIPI 456
                                                                    ::||:...:
 Worm   385 --------------------------------------------------------LDLPETHGV 393

  Fly   457 SVVPVPIMETKSVEASVELALDNAVFDDNEIEPNSDSVKERLELEVNLEGKQEPVANLSVDTMLD 521
             :.|.|:|       ..|:|.:|.:  .:.:.|                  :|||.:
 Worm   394 -IRPEPVM-------PAEIATENII--QSAVAP------------------EEPVPS-------- 422

  Fly   522 DDSLSPLSGVVNEPMECSSSITSQVSPREEEAIKVVADDVLMESVNDVHSMHVESGTSSPISNAE 586
              .|:.|:...::|||....:.||    |:|::..|.:||                 |:|:
 Worm   423 --ELNSLAAEYSQPMETEDPVESQ----EDESMVSVDEDV-----------------SAPV---- 460

  Fly   587 MREETEAQSDRTNDNNTIEGEGITVDD--------LVLLCDLFYLPFEHGSRGHKLLVEFNWLKG 643
                            .:.|...|.::        |...|:::|||||:|.|...:..:|.||..
 Worm   461 ----------------VLPGLATTAEEIRNQRLSLLCATCEMYYLPFENGPRVQSMFKDFRWLMQ 509

  Fly   644 NANVILQDRSAGGGGDAIKSDKPEVSEWHQRREQFDQLCSAVVELLIKIANCPNKEICHELYSYM 708
            ||:|:.:...      .|::..|..|||..:.:..::..::.::....|...|||.|..|:..|.
 Worm   510 NASVMKKSFK------EIETLDPLQSEWLVKYDGVNEFLTSAIDSFFFITQAPNKAILSEIVPYA 568

  Fly   709 WDISGALSLLNCYVKWLALGHF---PQNTSSYTEGSYTWFSKGWKEAFMSGDQEPWVFRGGLIAD 770
            :|......||....:|:..|:.   |:|......||               .:|.|:.:.|..::
 Worm   569 FDAHSCCVLLIAVARWMMQGNALDNPENNLFEDFGS---------------TEERWINQNGFRSE 618

  Fly   771 LQRLMPVDS------GNDLFVYKLPEQPTANY-YLLRPYCNSDEQQVNDLCTRLYLQWRGELDGG 828
            ..|::.|..      .|.:|:      |...: :.:||:..:|::.::.:.| :.|....||
 Worm   619 TMRVLNVVDDIEVLLSNKIFL------PLCMFCFDIRPFTIADKEYISGMVT-VMLTTNQEL--- 673

  Fly   829 RHIPFPLPANVPNIVADGLIGGYLTLSPQLCIVA--------YDESN---RIIGYSCAALDVNIF 882
                  |.....|.....:|       |.||..|        .||:.   |.:.|:.|..|..:|
 Worm   674 ------LHRRATNFADRNII-------PFLCSGAEHNFLCEKVDETGHKVRPVCYASAHFDGTLF 725

  Fly   883 RRNLELCWYTELREKYSRDICPLEGGEEVVQLVTSLVESYHDSSGNGALDQCPVEVSGSFPAV-- 945
             .|..:.:..:|:|||...|...:.|.      |.|.:.|.:...|   .|.|:::...:|.:
 Worm   726 -SNFLITYKEKLKEKYRGLIEDSKIGS------TKLTDEYIEFIQN---SQTPMDIEEWYPKIPD 780

  Fly   946 -LISG------TLREAEERDSGITKRMLTVLLAALRANGCFGAHVRVPQQDVAQVNFYSRIGFVD 1003
             :...      |....:..|:...::::.|:...|..||..|..:.|...|:.:..::..:|..|
 Worm   781 QIFENYPAWVETYFGMDASDAHPMRKVIQVVAVTLAMNGSRGYFLTVAIDDIERQKYFLELGLTD 845

  Fly  1004 V 1004
            :
 Worm   846 L 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oga	NP_650956.1	NAGidase	17..292	CDD:429533	139/274 (51%)
		RimI	<960..1019	CDD:440224	9/45 (20%)
oga-1	NP_001123184.1	NAGidase	20..306	CDD:429533	141/288 (49%)