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Protein Alignment Smyd5 and SMYD2

DIOPT Version :9

Sequence 1:	NP_650955.1	Gene:	Smyd5 / 42517	FlyBaseID:	FBgn0038869	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_064582.2	Gene:	SMYD2 / 56950	HGNCID:	20982	Length:	433	Species:	Homo sapiens

Alignment Length:	395	Identity:	84/395 - (21%)
Similarity:	136/395 - (34%)	Gaps:	171/395 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PGKGRAMIATKNFAKDEVIFEEEPFVSRQFSWNVAYGYAA--------CDHCMRPLETVLENVRR 66
            |||||.:.|.:.|...:::|.           ..||.|..        |::|....|.:
Human    15 PGKGRGLRALQPFQVGDLLFS-----------CPAYAYVLTVNERGNHCEYCFTRKEGL------ 62

  Fly    67 LASDPKVEVPLLQHDPTAQWVAQFTQCPRCK-VRYCSEDCLMEAQKR---YHRVACMGAFHSDDT 127
                                    ::|.||| ..||:.:|    ||.   .|::.|
Human    63 ------------------------SKCGRCKQAFYCNVEC----QKEDWPMHKLEC--------- 90

  Fly   128 HPINVLNETWKKMHYPPETGSIMLIVRLMA---LYQQSTKKEEFLEQLQSFQSLI--VNREQK-- 185
            .|:.|..|.|.    |.||  :.|..|::|   ::.:.|..|:.| .::.|:|.:  ::.|:|
Human    91 SPMVVFGENWN----PSET--VRLTARILAKQKIHPERTPSEKLL-AVKEFESHLDKLDNEKKDL 148

  Fly   186 ----------IYHKMLG--ENFEQQMEQLYLAF----CNAFTGEEFSIFKTPDAFKTLMAILGTN 234
                      .|.|.||  :|     :.|.:.|    ||.||.|:
Human   149 IQSDIAALHHFYSKHLGFPDN-----DSLVVLFAQVNCNGFTIED-------------------- 188

  Fly   235 SQGIATSVLSQWVAKVSDLPLTDSEKEQLDTVIDGLYAKVGEFAGEFLNNEGSGLYLLQSKINHS 299
                                                         |.|::.||.::...:.:|||
Human   189 ---------------------------------------------EELSHLGSAIFPDVALMNHS 208

  Fly   300 CVPNACSTFPYSNDIVVLKALAPIQQGEEICISYLDECMLERSRHSRHKVLRENYVFICQCPKCR 364
            |.||...|  |...:..::|:..|:.|||:..||:|.......|:.|   ||::|.|.|:|.:|.
Human   209 CCPNVIVT--YKGTLAEVRAVQEIKPGEEVFTSYIDLLYPTEDRNDR---LRDSYFFTCECQECT 268

  Fly   365 AQASD 369
            .:..|
Human   269 TKDKD 273

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.