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Protein Alignment Smyd5 and SMYD1

DIOPT Version :9

Sequence 1:	NP_650955.1	Gene:	Smyd5 / 42517	FlyBaseID:	FBgn0038869	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_938015.1	Gene:	SMYD1 / 150572	HGNCID:	20986	Length:	490	Species:	Homo sapiens

Alignment Length:	435	Identity:	90/435 - (20%)
Similarity:	132/435 - (30%)	Gaps:	175/435 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNNFEIRELPGKGRAMIATKNFAKDEVIFEEEPFVSRQFSWNVAYGYAACDHCMRPLETVLENVR 65
            |.|.|:....||||.:.|||.|...::||.|..:.:..|...|.:   .|..|.:..|
Human     6 MENVEVFTAEGKGRGLKATKEFWAADIIFAERAYSAVVFDSLVNF---VCHTCFKRQE------- 60

  Fly    66 RLASDPKVEVPLLQHDPTAQWVAQFTQCPRCK-VRYCSEDCLMEAQ----------KRYHRVACM 119
                                   :..:|.:|| ..||...|..:|.          |||.:|
Human    61 -----------------------KLHRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKRYGKV--- 99

  Fly   120 GAFHSDDTHPINVLNETWKKMHYPPETGSIMLIVRLM-ALYQQSTKKEE----FLEQLQSFQSLI 179
                                   |.|  :|.|..|:| .:.::.|...|    .::.||:.....
Human   100 -----------------------PNE--NIRLAARIMWRVEREGTGLTEGCLVSVDDLQNHVEHF 139

  Fly   180 VNREQKIYHKMLGENF-------EQQMEQLYLAF------CNAFTGEEFSIFKTPDAFKTLMAIL 231
            ...|||.. ::..:.|       .||....|::.      ||.||
Human   140 GEEEQKDL-RVDVDTFLQYWPPQSQQFSMQYISHIFGVINCNGFT-------------------- 183

  Fly   232 GTNSQGIATSVLSQWVAKVSDLPLTDSEKEQLDTVIDGLYAKVGEFAGEFLNNEGSGLYLLQSKI 296
                                   |:|..         ||.|            .|.|::.....:
Human   184 -----------------------LSDQR---------GLQA------------VGVGIFPNLGLV 204

  Fly   297 NHSCVPNACSTFPYSNDIVV-----------LKALAPIQQGEEICISYLDECMLERSRHSRHKVL 350
            ||.|.||....|...|...|           |:||..|.:|||:.:||:|  .|..| ..|.:.|
Human   205 NHDCWPNCTVIFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYID--FLNVS-EERKRQL 266

  Fly   351 RENYVFICQCPKCRAQASD------PDETSEDDDDDDEMDDYDDD 389
            ::.|.|.|.|..|:.:..|      .|......:...||..:..|
Human   267 KKQYYFDCTCEHCQKKLKDDLFLGVKDNPKPSQEVVKEMIQFSKD 311

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.