DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SNF4Agamma and prkag3

DIOPT Version :9

Sequence 1:	NP_001163671.1	Gene:	SNF4Agamma / 42515	FlyBaseID:	FBgn0264357	Length:	1400	Species:	Drosophila melanogaster
Sequence 2:	NP_001072406.2	Gene:	prkag3 / 779860	XenbaseID:	XB-GENE-965172	Length:	341	Species:	Xenopus tropicalis

Alignment Length:	318	Identity:	169/318 - (53%)
Similarity:	235/318 - (73%)	Gaps:	5/318 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   906 PFLEKVNLSDLEEDDSQIFVKFFRFHKCYDLIPTSAKLVVFDTQLLVKKAFYALVYNGVRAAPLW 970
            |..|..:|.    :|:.::::|...:.|||.||||.|||||||.|.:||||.|||.|||||||||
Frog    22 PMCEAPDLG----EDAGLYMEFMMKNCCYDAIPTSCKLVVFDTTLQIKKAFLALVANGVRAAPLW 82

  Fly   971 DSEKQQFVGMLTITDFIKILQMYYKSPNASMEQLEEHKLDTWRSV-LHNQVMPLVSIGPDASLYD 1034
            ||::..|||||||||||.||..|||:|...:.:|||||::|||.| |.:...||:.|.|..||:.
Frog    83 DSKQHSFVGMLTITDFINILHRYYKAPLVQIYELEEHKIETWREVYLQSSFKPLIYISPADSLFH 147

  Fly  1035 AIKILIHSRIHRLPVIDPATGNVLYILTHKRILRFLFLYINELPKPAYMQKSLRELKIGTYNNIE 1099
            |:..||.::||||||:||.:||:|:||||||:|:||.|:.:.||:|.::||::.||.|||:.::.
Frog   148 AVYSLIKNKIHRLPVMDPISGNILHILTHKRLLKFLHLFGDTLPRPRFLQKTILELGIGTFRDVA 212

  Fly  1100 TADETTSIITALKKFVERRVSALPLVDSDGRLVDIYAKFDVINLAAEKTYNDLDVSLRKANEHRN 1164
            ...:::|:..||:.||||||||||:|:..|::|.:|::||||:|||:|.||:||:|:|.|...|:
Frog   213 VVQDSSSVYNALEIFVERRVSALPVVNESGQVVGLYSRFDVIHLAAQKIYNNLDISVRDALRLRS 277

  Fly  1165 EWFEGVQKCNLDESLYTIMERIVRAEVHRLVVVDENRKVIGIISLSDILLYLVLRPSG 1222
            ...|||..|...|||..:::||||.::||||:|||:.:..||:||||||..|||.|:|
Frog   278 LSIEGVLMCYPHESLEVVIDRIVREQIHRLVLVDEDHRPRGIVSLSDILQALVLTPAG 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SNF4Agamma	NP_001163671.1	CBS_pair_5	941..1069	CDD:239990	80/128 (63%)
		CBS	952..1067	CDD:223591	71/115 (62%)
		CBS	1023..1141	CDD:223591	58/117 (50%)
		CBS_pair_28	1097..1215	CDD:240012	59/117 (50%)
		CBS	1097..1213	CDD:223591	57/115 (50%)
prkag3	NP_001072406.2	CBS_euAMPK_gamma-like_repeat1	45..181	CDD:341388	86/135 (64%)
		CBS repeat	52..125	CDD:341388	50/72 (69%)
		CBS repeat	137..181	CDD:341388	24/43 (56%)
		CBS_euAMPK_gamma-like_repeat2	207..330	CDD:341399	60/122 (49%)
		CBS repeat	208..273	CDD:341399	31/64 (48%)
		CBS repeat	284..327	CDD:341399	22/42 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8683
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000896
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X716
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000