DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SNF4Agamma and clcn6

DIOPT Version :9

Sequence 1:	NP_001163671.1	Gene:	SNF4Agamma / 42515	FlyBaseID:	FBgn0264357	Length:	1400	Species:	Drosophila melanogaster
Sequence 2:	XP_009302552.1	Gene:	clcn6 / 568122	ZFINID:	ZDB-GENE-030131-2056	Length:	863	Species:	Danio rerio

Alignment Length:	348	Identity:	59/348 - (16%)
Similarity:	119/348 - (34%)	Gaps:	119/348 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   899 RGLPV----ADPFLEKVNLSDLEEDDSQIFVKFFRFHKCYDLIPTSAKLVVFDTQLLVKKAFYAL 959
            :|:|:    .:..::|:..||:.|.:........|......::.|:           |..||..:
Zfish   577 KGVPLLEWETEVEMDKLTASDIMEPNLTYVYPHTRIQSLVSILRTT-----------VYHAFPVV 630

  Fly   960 VYNGVRAAPLWDSEKQQFVGMLTITDFIKILQMYYKSPNA------------SMEQLEEHKLDTW 1012
            ..|.       |:||:...|.:.|::.||     :|..:.            ||:.....:|
Zfish   631 TENR-------DNEKEFMKGNILISNNIK-----FKKTSVLTRAGEQRRRCQSMKSYPSSEL--- 680

  Fly  1013 RSVLHNQVMPLVSIGPDASLYDAIKILIHSRIHRLPVIDPAT--GNVLYILTHKRILRFLFLYIN 1075
            |:|....|                            |::|..  .::|..:..:|...:..||.:
Zfish   681 RNVCDEHV----------------------------VVEPTEEGQDILQQMLERRHAPYPNLYPD 717

  Fly  1076 ELPKPAY-MQKSLRELKIGTYNNIETADETTSIITALKKFVERRVSALPLVDSDGRLVDIYAKFD 1139
            :.|...: |::..|.|   |::.:....:..:::.....:.|.:.||.....|...:.:.|.:|.
Zfish   718 QSPSEEWTMEERFRPL---TFHGLILRSQLVNLLIRGVCYAENQSSASQPRLSHSEMTEDYPRFP 779

  Fly  1140 VINLAAEKTYNDLDVSLR-------------------KANEHRNEWFEGVQKCNLDESLYTIMER 1185
            .|        :|||::|.                   ..|.|.::.|          :|:..|
Zfish   780 DI--------HDLDLALLNPRMIVDVTPYMNPCPYTVSPNTHVSQVF----------NLFRTM-- 824

  Fly  1186 IVRAEVHRLVVVDENRKVIGIIS 1208
                .:..|.||:...:::|||:
Zfish   825 ----GLRHLPVVNAVGEIVGIIT 843

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SNF4Agamma	NP_001163671.1	CBS_pair_5	941..1069	CDD:239990	22/141 (16%)
		CBS	952..1067	CDD:223591	22/128 (17%)
		CBS	1023..1141	CDD:223591	17/120 (14%)
		CBS_pair_28	1097..1215	CDD:240012	22/131 (17%)
		CBS	1097..1213	CDD:223591	22/131 (17%)
clcn6	XP_009302552.1	ClC_6_like	45..582	CDD:239657	2/4 (50%)
		Voltage_CLC	135..564	CDD:279048
		CBS	595..>633	CDD:278968	8/48 (17%)
		CBS_pair_EriC_assoc_euk_bac	688..847	CDD:239964	34/211 (16%)
		CBS	797..>847	CDD:223591	11/63 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910