DRSC/TRiP Functional Genomics Resources

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Protein Alignment SNF4Agamma and PRKAG1

DIOPT Version :9

Sequence 1:NP_001163671.1 Gene:SNF4Agamma / 42515 FlyBaseID:FBgn0264357 Length:1400 Species:Drosophila melanogaster
Sequence 2:XP_005269076.1 Gene:PRKAG1 / 5571 HGNCID:9385 Length:368 Species:Homo sapiens


Alignment Length:333 Identity:192/333 - (57%)
Similarity:236/333 - (70%) Gaps:23/333 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   899 RGLPVADPFLEKVNLSDLEEDDSQIFVKFFRFHKCY-DLIPTSAKLVVFDTQLLVKKAFYALVYN 962
            |||| .:.||::.|.:.          :..::.:.: .:.|...|:.:    |.|||||:|||.|
Human    55 RGLP-QESFLKRGNQAG----------RLLQWRRSFLQIAPQLWKMSI----LKVKKAFFALVTN 104

  Fly   963 GVRAAPLWDSEKQQFVGMLTITDFIKILQMYYKSPNASMEQLEEHKLDTWRSV-LHNQVMPLVSI 1026
            ||||||||||:||.|||||||||||.||..||||....:.:|||||::|||.| |.:...|||.|
Human   105 GVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCI 169

  Fly  1027 GPDASLYDAIKILIHSRIHRLPVIDPATGNVLYILTHKRILRFLFLYINELPKPAYMQKSLRELK 1091
            .|:|||:||:..||.::|||||||||.:||.||||||||||:||.|:|.|.|||.:|.|||.||:
Human   170 SPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQ 234

  Fly  1092 IGTYNNIETADETTSIITALKKFVERRVSALPLVDSDGRLVDIYAKFDVINLAAEKTYNDLDVSL 1156
            ||||.||.....||.:..||..||:.||||||:||..||:||||:||||||||||||||:||||:
Human   235 IGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSV 299

  Fly  1157 RKANEHRNEWFEGVQKCNLDESLYTIMERIVRAEVHRLVVVDENRKVIGIISLSDILLYLVLRPS 1221
            .||.:||:.:||||.||.|.|:|.||:.|:|.||||||||||||..|.||:||||||..|||   
Human   300 TKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL--- 361

  Fly  1222 GEGVGGSE 1229
               .||.:
Human   362 ---TGGEK 366

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SNF4AgammaNP_001163671.1 CBS_pair_5 941..1069 CDD:239990 83/128 (65%)
CBS 952..1067 CDD:223591 79/115 (69%)
CBS 1023..1141 CDD:223591 75/117 (64%)
CBS_pair_28 1097..1215 CDD:240012 78/117 (67%)
CBS 1097..1213 CDD:223591 76/115 (66%)
PRKAG1XP_005269076.1 CBS_pair_5 92..212 CDD:239990 82/119 (69%)
CBS 93..210 CDD:223591 79/116 (68%)
CBS 164..284 CDD:223591 76/119 (64%)
CBS_pair_28 239..358 CDD:240012 78/118 (66%)
CBS 240..356 CDD:223591 76/115 (66%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 78 1.000 Domainoid score I8779
eggNOG 1 0.900 - - E1_COG0517
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S1437
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000896
OrthoInspector 1 1.000 - - otm40465
orthoMCL 1 0.900 - - OOG6_101734
Panther 1 1.100 - - O PTHR13780
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X716
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
109.720

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