DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SNF4Agamma and prkag3a

DIOPT Version :9

Sequence 1:	NP_001163671.1	Gene:	SNF4Agamma / 42515	FlyBaseID:	FBgn0264357	Length:	1400	Species:	Drosophila melanogaster
Sequence 2:	XP_005160349.1	Gene:	prkag3a / 553319	ZFINID:	ZDB-GENE-091204-419	Length:	349	Species:	Danio rerio

Alignment Length:	345	Identity:	181/345 - (52%)
Similarity:	244/345 - (70%)	Gaps:	23/345 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   884 GTLDPHHAAILFRDSRGLPVADPFLEKVNLSDLEEDDSQIFVKFFRFHKCYDLIPTSAKLVVFDT 948
            ||.|..|...|                ||::|| :.:::.::.|.:.|.|||.||||.|||:|||
Zfish    16 GTQDDCHEDCL----------------VNITDL-DPNAETYMNFMKKHCCYDAIPTSCKLVIFDT 63

  Fly   949 QLLVKKAFYALVYNGVRAAPLWDSEKQQFVGMLTITDFIKILQMYYKSPNASMEQLEEHKLDTWR 1013
            .|.|||||:|||.||:|||||||.:.|:|||||||||||.||..||:||...:.:|||||::|||
Zfish    64 TLQVKKAFFALVANGLRAAPLWDHKLQRFVGMLTITDFINILHRYYRSPMVQIYELEEHKIETWR 128

  Fly  1014 S------VLHNQVMPLVSIGPDASLYDAIKILIHSRIHRLPVIDPATGNVLYILTHKRILRFLFL 1072
            .      .|..|...|:||.|||||:||:..|:..:|||||||||.:||||:||||||||:||.:
Zfish   129 GDSFQNVYLQYQDQCLISITPDASLFDAVYSLLKHKIHRLPVIDPESGNVLHILTHKRILKFLHI 193

  Fly  1073 YINELPKPAYMQKSLRELKIGTYNNIETADETTSIITALKKFVERRVSALPLVDSDGRLVDIYAK 1137
            :...:|||.:::..::|..|||:.::.|..:|.::..||..||||||||||:||.||::|.:|::
Zfish   194 FGTTVPKPRFLKMQIKEAGIGTFRDVATVSQTATVYDALSVFVERRVSALPVVDDDGKVVALYSR 258

  Fly  1138 FDVINLAAEKTYNDLDVSLRKANEHRNEWFEGVQKCNLDESLYTIMERIVRAEVHRLVVVDENRK 1202
            ||||||||:||||:|.:|:::|...|..:.|||.||..||:|.|:::|||:|||||||:||....
Zfish   259 FDVINLAAQKTYNNLSMSMQEAVRRRRCYVEGVIKCYPDETLETVIDRIVKAEVHRLVLVDREDV 323

  Fly  1203 VIGIISLSDILLYLVLRPSG 1222
            |.|||||||:|..:||.|:|
Zfish   324 VRGIISLSDLLQAIVLSPAG 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SNF4Agamma	NP_001163671.1	CBS_pair_5	941..1069	CDD:239990	84/133 (63%)
		CBS	952..1067	CDD:223591	75/120 (63%)
		CBS	1023..1141	CDD:223591	63/117 (54%)
		CBS_pair_28	1097..1215	CDD:240012	66/117 (56%)
		CBS	1097..1213	CDD:223591	65/115 (57%)
prkag3a	XP_005160349.1	CBS_pair_5	57..190	CDD:239990	84/132 (64%)
		CBS	67..188	CDD:223591	75/120 (63%)
		CBS	144..262	CDD:223591	63/117 (54%)
		CBS_pair_28	217..336	CDD:240012	66/118 (56%)
		CBS	217..334	CDD:223591	65/116 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	64	1.000	Domainoid score	I10121
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000896
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13780
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X716
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.010