Protein Alignment SNF4Agamma and aakg-1

DIOPT Version :10

• Sequence 1: NP_732598.1
• Gene: SNF4Agamma / 42515
• FlyBaseID: FBgn0264357
• Length: 1400
• Species: Drosophila melanogaster
• Sequence 2: NP_001368643.1
• Gene: aakg-1 / 3565679
• WormBaseID: WBGene00013732
• Length: 801
• Species: Caenorhabditis elegans
• Alignment Length: 870
• Identity: 294/870 - (33%)
• Similarity: 420/870 - (48%)
• Gaps: 168/870 - (19%)

  Fly   525 LRSESSASTTSP-SRQLTNSGSVSVSVSDDEQDGSLGGAGRMPGSRPSSAPAEPNAKAAKKAYKK 588
            ||..|:.|.||| :|.:.:..||.|...:.:|..:.|      ..||.:..|.|.....
 Worm     4 LRQSSATSPTSPVARNVYSRASVDVETGEIQQQQNSG------HKRPYTPGASPREILC------ 56

  Fly   589 MEKEQRRQEKEQSRREKEARKLERETARRNEREAAKLEKINRHSEKISRSTERMAMAGV------ 647
             .::..||....|:......:. .:..||..|:|:    :|..||.:  ..|.:....|
 Worm    57 -AQQSLRQLPSPSQTSPHGSRF-MDGYRRRMRQAS----LNLPSETL--LDEDLGFPPVCSPPPE 113

  Fly   648 ---GSRSGSLERRRS-GEDSPVLNQSTVHGIASPNRRPTIFDVFRPRAKSDAKRQKEKHLLD--- 705
               ||..|:..|.|| .|..|.|...:.|.:.:..     ..||.|.:.|.:. ....|||.
 Worm   114 VFCGSIVGNQMRNRSNSEAQPGLRMRSSHSLGNGG-----LLVFFPTSPSSSS-NNSGHLLQHRR 172

  Fly   706 PSSADSSATSS-TYSVSGGT-------------------------GPATSSAAGGA--------- 735
            .|..|.:|..: .:|.:..|                         .|....||||:
 Worm   173 ESHTDETAEEAIIWSTNNDTSDEMMDETSCCMVADDISMKDVEMPSPIIGGAAGGSKSLKRPPDL 237

  Fly   736 -GGAAAAAGQGAAGGA-GGLMNSMKVAMQNFSHRQHPAVTITSADGTQSTAKSKYKDGSAHPHQG 798
             |...:.:...::||| .|:..|......::|.|..|....|.               .|:..|.
 Worm   238 NGSNNSGSSSSSSGGANSGVQQSSVHPSNSYSPRSRPLFVDTQ---------------MANHLQD 287

  Fly   799 SDAQYYHTVTAVRPNSSQRSPMTKVMDLFRHR--------SSSVVSEADKRKARAAAH------- 848
            |             |..:|||:::|:|..|.|        |||.:.......|||:|.
 Worm   288 S-------------NMKRRSPVSQVVDFVRGRNRTYSLQLSSSPMCSPQSVAARASASCDGCNGP 339

  Fly   849 --QQQLAVQSAHMRRASADLEKRRASVGAAGRGLRGDGTLD---P--HHAAILFR--------DS 898
              ..|....|...||.:......|||..|.|.....|..||   |  :|.|:|.:        ||
 Worm   340 PPPPQPIGMSPSGRRQTISGRVHRASFTAGGTLKSFDSGLDLSSPTINHTALLIKEASLFSSFDS 404

  Fly   899 RGLPVADPFLEKVNLSDLEEDDSQIFVKFFRFHKCYDLIPTSAKLVVFDTQLLVKKAFYALVYNG 963
            ..:..|.|   .:|....:..|: ::..|.:.||||||||||:|||||||.|.|:||||||||||
 Worm   405 MSIGTAVP---DINAIFFDNHDA-VYSLFMKAHKCYDLIPTSSKLVVFDTHLPVRKAFYALVYNG 465

  Fly   964 VRAAPLWDSEKQQFVGMLTITDFIKILQMYY-KSPNAS-MEQLEEHKLDTWRS--VLHNQVMPLV 1024
            ||||||||::.|:|.||||||||||||..:| |..|:. :..||:.::..||.  .|...:.|.|
 Worm   466 VRAAPLWDTDNQRFTGMLTITDFIKILCKHYDKGDNSERIRALEDQQISHWRDQFELDGTLRPFV 530

  Fly  1025 SIGPDASLYDAIKILIHSRIHRLPVIDPATGNVLYILTHKRILRFLFLYINELPKPAYMQKSLRE 1089
            .|.|:.||:.|:::|..|::|||||:|..|||:.||||||||::||.||:.:||:|::|..:.||
 Worm   531 YIDPNESLHRAVELLCESKVHRLPVLDRKTGNITYILTHKRIMKFLSLYMRDLPRPSFMSCTPRE 595

  Fly  1090 LKIGTYNNIETADETTSIITALKKFVERRVSALPLVDSDGRLVDIYAKFDVINLAAEKTYNDLDV 1154
            |.||.:.:|......|.|..||:.|::.|||||||:|.:||:||||||||||:||||.:|:.||.
 Worm   596 LGIGAWGDILCCHVDTPIHDALELFLKNRVSALPLIDENGRVVDIYAKFDVISLAAESSYDKLDC 660

  Fly  1155 SLRKANEHRNEWFEGVQKCNLDESLYTIMERIVRAEVHRLVVVDENRKVIGIISLSDILLYLVLR 1219
            ::::|.:||:|||||||.|...:||:.::|.||:||||||:|.|:::||:|::||||||..|||.
 Worm   661 TVQEALQHRSEWFEGVQTCLETDSLFQVLEAIVKAEVHRLIVTDQDKKVVGVVSLSDILKNLVLD 725

  Fly  1220 P----------SGEGVGGSESSLRASDPVLLRKVAEVEIPATAAAATTTTPPRSPSAGSGNRSLI 1274
            |          |.:..||...:..||.            .:|..|:::.:||.|...|.   .:.
 Worm   726 PCQKPPPPPPQSQQAGGGGPPTRNASG------------TSTGGASSSDSPPHSIPEGI---EVE 775

  Fly  1275 EDIPEEETAPARSDDADSDNNKSAS 1299
            :|..::|.||..|.|..:....||:
 Worm   776 DDDDDDEEAPPPSIDCSTPGPSSAA 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SNF4Agamma	NP_732598.1	CBS_euAMPK_gamma-like_repeat1	932..1068	CDD:341388	84/139 (60%)
		CBS repeat	940..1013	CDD:341388	47/74 (64%)
		CBS repeat	1024..1068	CDD:341388	25/43 (58%)
		CBS_euAMPK_gamma-like_repeat2	1094..1217	CDD:341399	66/122 (54%)
		CBS repeat	1095..1160	CDD:341399	33/64 (52%)
		CBS repeat	1171..1214	CDD:341399	23/42 (55%)
aakg-1	NP_001368643.1	CBS_euAMPK_gamma-like_repeat1	434..574	CDD:341388	84/139 (60%)
		CBS repeat	442..517	CDD:341388	47/74 (64%)
		CBS repeat	530..574	CDD:341388	25/43 (58%)
		CBS_euAMPK_gamma-like_repeat2	601..723	CDD:341399	66/121 (55%)
		CBS repeat	601..666	CDD:341399	33/64 (52%)
		CBS repeat	677..720	CDD:341399	23/42 (55%)