DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SNF4Agamma and prkag1

DIOPT Version :9

Sequence 1:	NP_001163671.1	Gene:	SNF4Agamma / 42515	FlyBaseID:	FBgn0264357	Length:	1400	Species:	Drosophila melanogaster
Sequence 2:	NP_001096506.1	Gene:	prkag1 / 100125135	XenbaseID:	XB-GENE-943598	Length:	334	Species:	Xenopus tropicalis

Alignment Length:	311	Identity:	199/311 - (63%)
Similarity:	241/311 - (77%)	Gaps:	1/311 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   914 SDLEEDDSQIFVKFFRFHKCYDLIPTSAKLVVFDTQLLVKKAFYALVYNGVRAAPLWDSEKQQFV 978
            ||:.|.||.::.:|.:.||||||||.|:|||||||.|.|||||:|||.|||||||||||:||.||
Frog    20 SDVLESDSGVYTRFMKNHKCYDLIPISSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQGFV 84

  Fly   979 GMLTITDFIKILQMYYKSPNASMEQLEEHKLDTWRSV-LHNQVMPLVSIGPDASLYDAIKILIHS 1042
            |||||||||.||..|||||...:.:|||||::|||.: |.:...|||||.|.|||:||:..||.:
Frog    85 GMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQDSFKPLVSISPSASLFDAVSSLIKN 149

  Fly  1043 RIHRLPVIDPATGNVLYILTHKRILRFLFLYINELPKPAYMQKSLRELKIGTYNNIETADETTSI 1107
            ||||||||.|.:||.||||||||||:||.|:::|:.|||::.|||::|.||||.||......|.:
Frog   150 RIHRLPVISPDSGNTLYILTHKRILKFLKLFMSEVEKPAFVTKSLKDLHIGTYENIALVRPDTPV 214

  Fly  1108 ITALKKFVERRVSALPLVDSDGRLVDIYAKFDVINLAAEKTYNDLDVSLRKANEHRNEWFEGVQK 1172
            ..||..||:|||||||:||..||:||||:||||||||||||||:||:::.||..||:.:||||.|
Frog   215 YVALGIFVQRRVSALPVVDDSGRVVDIYSKFDVINLAAEKTYNNLDITVTKALGHRSHYFEGVLK 279

  Fly  1173 CNLDESLYTIMERIVRAEVHRLVVVDENRKVIGIISLSDILLYLVLRPSGE 1223
            |...|:|.||:.|:|.||||||||||||....||:||||||..|||...||
Frog   280 CYQHETLETIINRLVEAEVHRLVVVDENDVAKGIVSLSDILQCLVLTAGGE 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SNF4Agamma	NP_001163671.1	CBS_pair_5	941..1069	CDD:239990	90/128 (70%)
		CBS	952..1067	CDD:223591	80/115 (70%)
		CBS	1023..1141	CDD:223591	73/117 (62%)
		CBS_pair_28	1097..1215	CDD:240012	74/117 (63%)
		CBS	1097..1213	CDD:223591	72/115 (63%)
prkag1	NP_001096506.1	CBS_euAMPK_gamma-like_repeat1	38..175	CDD:341388	97/136 (71%)
		CBS repeat	46..119	CDD:341388	54/72 (75%)
		CBS repeat	131..175	CDD:341388	31/43 (72%)
		CBS_euAMPK_gamma-like_repeat2	201..324	CDD:341399	76/122 (62%)
		CBS repeat	202..267	CDD:341399	40/64 (63%)
		CBS repeat	278..321	CDD:341399	27/42 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4230
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030