Protein Alignment Snmp1 and Scarb2

DIOPT Version :10

• Sequence 1: NP_650953.1
• Gene: Snmp1 / 42514
• FlyBaseID: FBgn0260004
• Length: 551
• Species: Drosophila melanogaster
• Sequence 2: NP_446453.1
• Gene: Scarb2 / 117106
• RGDID: 621882
• Length: 478
• Species: Rattus norvegicus
• Alignment Length: 471
• Identity: 118/471 - (25%)
• Similarity: 214/471 - (45%)
• Gaps: 64/471 - (13%)

  Fly    26 IFPKILKFMISKQVTLKPGSDVRELWSNTPFPLHFYIYVFNVTNPDEVSEGAKPRLQEVGPFVFD 90
            :|.|.:...|.|.:.|:.|:.|.:.|...|.|::...|.||||||:|:.:|..|.|:||||:.:.
  Rat    28 VFQKAVDQTIEKNMVLQNGTKVFDSWEKPPLPVYIQFYFFNVTNPEEILQGEIPLLEEVGPYTYR 92

  Fly    91 EWKDKYDLEDDVVEDTVSFTMRNTFIFNPKESLPLTGEEEIILPHPIMLPGGISVQ-REKAAMME 154
            |.::|.:::......|:|......:||...:|:   |:..:.|...|.:|....|: .::..:.|
  Rat    93 ELRNKANVQFGENGTTISAVTNKAYIFERNQSV---GDPTVDLIRTINIPLLTVVEMAQQPFLRE 154

  Fly   155 LVSKGLSIVFPDAKAFLKAKFMDLFFRGINVDCSSEEFSAKALCTVF-----YTGEIKQAKQVNQ 214
            ::           :|.|||....||                ...||.     |..|:     ::.
  Rat   155 II-----------EAMLKAYQQTLF----------------VTHTVHELLWGYKDEV-----LSL 187

  Fly   215 THFL-------FSFMGQANHSDSGRFTVCRGVKNNKKLGKVVKFADEPEQDIWPDGECNTFVGTD 272
            .|..       |....:.|.::.|.:....|..|.....|:|::..:...|.|....||...|||
  Rat   188 VHIFRPDVSPNFGLFYERNGTNDGEYVFLTGEDNYLNFTKIVEWNGKTSLDWWTTDTCNMINGTD 252

  Fly   273 STVFAPGLKKEDGLWAFTPDLCRSLGAYYQHKSSYHGMPSMRYTLDLGDIRADEKLHC-FCEDPE 336
            ...|.|.:.|::.|:.|..|.|||:...:....:..|:|:.||.:. .:|.|:...:. || .||
  Rat   253 GDSFHPLISKDETLYIFPSDFCRSVYITFSSFENVEGLPAFRYKVP-AEILANSSENAGFC-IPE 315

  Fly   337 DLDTCPPKGTMNLAACV-GGPLMASMPHFYLGDPKLVADVDGLNPNEKDHAVYIDFELMSGTPFQ 400
              ..|...|.:|::.|. |.|::.|.||||..|.|.|:.:.|:.||:::|..::|...::|...:
  Rat   316 --GNCMDAGVLNVSICKNGAPIIMSFPHFYQADEKFVSAIKGMRPNKEEHESFVDINPLTGIILR 378

  Fly   401 AAKRLQFNLDMEPVEGIEPMKNLPKLILPMFWVEEGVQLNKTYTNLVKYTLFLGLKINSVLRWSL 465
            .|||.|.|..::.::......|:..::.|:.::.|.|.::|...:.:|          ||:..:|
  Rat   379 GAKRFQINTYVKKLDDFVETGNIRTMVFPVMYLNESVLIDKETASQLK----------SVINTTL 433

  Fly   466 ITFSLVGLMFSAYLFY 481
            |..::..::.:..:|:
  Rat   434 IVTNIPYIIMALGVFF 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snmp1	NP_650953.1	CD36	11..480	CDD:460076	117/468 (25%)
Scarb2	NP_446453.1	CD36	28..457	CDD:460076	118/471 (25%)
		Important for interaction with GBA1. /evidence=ECO:0000250	155..191		11/67 (16%)