DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5810 and 2mit

DIOPT Version :9

Sequence 1:NP_650952.2 Gene:CG5810 / 42513 FlyBaseID:FBgn0038866 Length:428 Species:Drosophila melanogaster
Sequence 2:NP_001262529.1 Gene:2mit / 41616 FlyBaseID:FBgn0260793 Length:1155 Species:Drosophila melanogaster


Alignment Length:392 Identity:90/392 - (22%)
Similarity:159/392 - (40%) Gaps:120/392 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    91 EFHV---LECELQQIESVCFDGAKNLKRLNFGGNALRVL-----DSNTFELATQLEELNLSDNQL 147
            :|.|   ::....|:||:..|....|::|:.|.|:|.|:     |:|   ::.....|:||.|:.
  Fly   119 DFQVITAMDLSSNQLESLSLDNFNQLRQLDLGNNSLEVIPLSLADTN---MSLPFVTLDLSCNKF 180

  Fly   148 EDLPTTIF-RPLKNLQKINLSNNRLITLSQHIFSQLGSLKSINVDSNQLVELPGELFRDQRKHLS 211
            ..:.|:.| :.|..|:.:||::|.|:.:|:..|..|..|:::.:..|.:.::..|.|. ...:|.
  Fly   181 SQISTSFFAQRLPQLKNLNLAHNELLNISRESFYNLLELQTLVLSHNNISDIDYETFL-ALPNLQ 244

  Fly   212 EFSAQSNQL----VR----IPFNIFREIDHLSLSFNP---------------------------- 240
            ......|:|    :|    ||     ::..||:::||                            
  Fly   245 YLDLSHNRLSGSAIRALQGIP-----DLVSLSIAYNPDVGVAMQEFVASWSLKELDASGTGLCQV 304

  Fly   241 ------QLRRLHLSAKINELEATNC-DLESVEL-------DGRVIGVQLEANPKLHELK------ 285
                  .:|.|.||.  |.|:|.|| |::|..|       ..|:..|:.:|..:|..|:      
  Fly   305 PAALAQSVRTLKLSD--NWLKAINCGDMDSYPLLQYLDLSHSRIAQVEDDALGRLELLESLFLDR 367

  Fly   286 -------ISQPQDLEHLYLANTNLYRLD---FLSKASKLVDLDVTDIVN--LADLPKITSAK--- 335
                   .|.|..||||:|.:..:..|.   |:.    ||:|...|:.|  |..||.::..|   
  Fly   368 NLLMRVPSSLPPSLEHLFLQHNQIMELPPQAFVG----LVNLQTLDLSNNRLIFLPPLSLPKLLT 428

  Fly   336 -GLERLSFTYDNLTSNHMDMLPHLKDLNYLEISHEKGKEIFIKDLDEDFFVEEAELNCGQLADLL 399
             .||  |...::::.:.:..||.|:||                      .:|:..:.|..|..:.
  Fly   429 LNLE--SSGVESVSQSIVHTLPQLRDL----------------------LLEDNPIKCSDLLGIA 469

  Fly   400 EF 401
            |:
  Fly   470 EW 471

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5810NP_650952.2 leucine-rich repeat 65..88 CDD:275380
LRR_8 87..147 CDD:290566 18/63 (29%)
leucine-rich repeat 89..112 CDD:275380 6/23 (26%)
leucine-rich repeat 113..136 CDD:275380 8/27 (30%)
LRR_8 135..195 CDD:290566 17/60 (28%)
LRR_4 135..175 CDD:289563 12/40 (30%)
leucine-rich repeat 137..160 CDD:275380 7/23 (30%)
leucine-rich repeat 161..184 CDD:275380 8/22 (36%)
leucine-rich repeat 185..209 CDD:275380 4/23 (17%)
leucine-rich repeat 210..231 CDD:275380 6/28 (21%)
2mitNP_001262529.1 LRR_RI 124..355 CDD:238064 56/241 (23%)
leucine-rich repeat 124..143 CDD:275380 4/18 (22%)
leucine-rich repeat 144..167 CDD:275380 8/25 (32%)
leucine-rich repeat 172..194 CDD:275380 7/21 (33%)
LRR_8 193..253 CDD:290566 14/60 (23%)
leucine-rich repeat 195..218 CDD:275380 8/22 (36%)
leucine-rich repeat 219..242 CDD:275380 4/23 (17%)
LRR_8 241..301 CDD:290566 10/64 (16%)
leucine-rich repeat 243..311 CDD:275380 10/72 (14%)
leucine-rich repeat 312..335 CDD:275380 11/24 (46%)
LRR_8 334..415 CDD:290566 20/84 (24%)
leucine-rich repeat 336..359 CDD:275380 4/22 (18%)
leucine-rich repeat 360..380 CDD:275380 3/19 (16%)
LRR_8 379..460 CDD:290566 25/108 (23%)
LRR_4 379..>415 CDD:289563 12/39 (31%)
leucine-rich repeat 381..404 CDD:275380 8/26 (31%)
leucine-rich repeat 405..449 CDD:275380 11/45 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453504
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.030

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