DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5810 and CG42709

DIOPT Version :9

Sequence 1:	NP_650952.2	Gene:	CG5810 / 42513	FlyBaseID:	FBgn0038866	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001163434.1	Gene:	CG42709 / 39453	FlyBaseID:	FBgn0261674	Length:	458	Species:	Drosophila melanogaster

Alignment Length:	354	Identity:	77/354 - (21%)
Similarity:	125/354 - (35%)	Gaps:	91/354 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 NYILIAVIAFATCESQKLEEIAIDSLDCRENTCTNLKYPSASAVAYFSENVTKHLRKYETLVLHS 72
            |.:.:....|..|.:..|..:.:|             .|..:|:...|.||...||        .
  Fly    96 NCLCLEDFKFVQCANAHLTHVPLD-------------MPKTAAIIDLSHNVIAELR--------P 139

  Fly    73 SDLANLPRKIFLNLPQLVEFHVLECELQQIESVCFDGAKNLKRLNFGGNALRVLDSNTFELATQL 137
            .|.|||.|.:.:||.     |.|   :..|:...|.|::.||||....|.|..:|.:||..|.:|
  Fly   140 EDFANLSRAVEINLN-----HNL---ISSIDKDVFQGSERLKRLRLANNRLTKIDPDTFAAAKEL 196

  Fly   138 EELNLSDNQLEDLPTTIFRPLKNLQKINLSNNRLITLSQHIFSQLGSLKSINVDSNQLVELPGEL 202
            ..|:||:|.:.......|....:|.:.:..|.....|.:..|..:..|:.:.::.|
  Fly   197 TLLDLSNNTITQRLDGSFLNQPDLVEFSCVNCSWTELPEQTFQNMSGLEVLRLNKN--------- 252

  Fly   203 FRDQRKHLSEFSAQSNQLVRIPFNIFREIDHLSLSFNPQLRRLH------LSAKINELEATNCDL 261
                     :|..|.|...   |:...:|..|.|   |:|.:.:      |...|:.:...|.|:
  Fly   253 ---------DFKQQINTKA---FSPLTKIIKLKL---PELEQQNIEELCSLLTSIDTISFLNYDI 302

  Fly   262 ESVELDGRVIGVQLEAN---PKLHELK-ISQPQDLEHL--------------YLANTNLYRLDFL 308
            ...|.   |:|.....:   |....|| |:.|..:..:              ..||.|..::|
  Fly   303 SCYEF---VLGTPFNGSLIYPTEPPLKGITNPPIVASITSTAKPVTATPAPPRSANRNRGKMD-- 362

  Fly   309 SKASKLVDLDVTDIVNLADLPKITSAKGL 337
                     :.|::|....|...||..|:
  Fly   363 ---------NSTELVKAGILSSETSTSGV 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5810	NP_650952.2	leucine-rich repeat	65..88	CDD:275380	7/22 (32%)
		LRR_8	87..147	CDD:290566	20/59 (34%)
		leucine-rich repeat	89..112	CDD:275380	5/22 (23%)
		leucine-rich repeat	113..136	CDD:275380	10/22 (45%)
		LRR_8	135..195	CDD:290566	12/59 (20%)
		LRR_4	135..175	CDD:289563	8/39 (21%)
		leucine-rich repeat	137..160	CDD:275380	6/22 (27%)
		leucine-rich repeat	161..184	CDD:275380	4/22 (18%)
		leucine-rich repeat	185..209	CDD:275380	2/23 (9%)
		leucine-rich repeat	210..231	CDD:275380	4/20 (20%)
CG42709	NP_001163434.1	LRR_8	126..182	CDD:290566	22/71 (31%)
		leucine-rich repeat	128..147	CDD:275380	9/26 (35%)
		leucine-rich repeat	148..171	CDD:275380	7/30 (23%)
		LRR_RI	<150..225	CDD:238064	24/82 (29%)
		LRR_8	171..254	CDD:290566	22/100 (22%)
		leucine-rich repeat	172..195	CDD:275380	10/22 (45%)
		leucine-rich repeat	196..219	CDD:275380	6/22 (27%)
		leucine-rich repeat	220..243	CDD:275380	4/22 (18%)
		leucine-rich repeat	244..268	CDD:275380	6/44 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453628
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930