DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5810 and conv

DIOPT Version :9

Sequence 1:	NP_650952.2	Gene:	CG5810 / 42513	FlyBaseID:	FBgn0038866	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001286416.1	Gene:	conv / 36588	FlyBaseID:	FBgn0261269	Length:	1092	Species:	Drosophila melanogaster

Alignment Length:	370	Identity:	92/370 - (24%)
Similarity:	167/370 - (45%)	Gaps:	45/370 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LRKYETLVLHSSDLANLPRKIFLNLPQLVEFHVLECELQQIESVCFDGAKNLKRLNFGGNALRVL 126
            |||.:||.||.:.|.||.|..|.||.:|....:...:::::|:........|...|...|||..|
  Fly   197 LRKLKTLDLHGNQLENLKRNQFKNLRELEVLDISHNQIKKLEAQHIADLTKLGWCNVSHNALSEL 261

  Fly   127 DSNTFELATQLEELNLSDNQLEDLPTTIFRPLKNLQKINLSNNRLITLSQHIFSQLGSLKSINVD 191
            ...||...:.|:.|:||.||:..|....||.::.|:::.||:|.|..:.:..|..:..:.:|::.
  Fly   262 SRGTFARNSVLKVLHLSHNQIARLDANSFRGMRFLRRLFLSDNVLTDIGRGTFGSIARIGTIDLA 326

  Fly   192 SNQLVELPGELFRDQRKHLSEFSAQSNQLVRIPFNIFREIDHLSLSFNPQLRRLHLSAKINELEA 256
            .|:|.::..::| .|..::.......|.:.:|..|.|::|....::.:      |.:.::.|..|
  Fly   327 RNRLKKIEFQMF-TQMNYVELLDLAENNITKIEKNSFKDIYQAIINVS------HNALELIETAA 384

  Fly   257 -TNCDLESVELDGRVIGVQLEANPKLHELKISQPQDLEHLYLANTNLYRLDFLSKASKLVDLDVT 320
             .||           :.:.:              .||.|..|||.:....|..:.|: ...|...
  Fly   385 FENC-----------VNITV--------------LDLSHNRLANFSRRSFDETTFAT-YFQLSYN 423

  Fly   321 DIVNLADLPKITSAKGLERLSFTYDNLTSNHMDMLPHLKDLNYLEISHEKGKEIFIKDLDEDFFV 385
            ::.|||.:| |.:..||:.|:.:|:::|....:..|.|.:|:.:::||.....||.......|.:
  Fly   424 NLTNLAQIP-IQNMTGLKVLNASYNSITEIPKNCFPKLYELHTIDVSHNNISSIFNGVFQTLFSL 487

  Fly   386 EEAELNCGQLADLLE--FVELPKDTTILE-----DRLVGDPRGPM 423
            ...:|:...:.::..  |..||   |:||     :.||...||.:
  Fly   488 RSIDLSHNSMREIKSSTFGTLP---TLLEMDLSHNELVSVVRGSL 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5810	NP_650952.2	leucine-rich repeat	65..88	CDD:275380	11/22 (50%)
		LRR_8	87..147	CDD:290566	15/59 (25%)
		leucine-rich repeat	89..112	CDD:275380	2/22 (9%)
		leucine-rich repeat	113..136	CDD:275380	8/22 (36%)
		LRR_8	135..195	CDD:290566	17/59 (29%)
		LRR_4	135..175	CDD:289563	14/39 (36%)
		leucine-rich repeat	137..160	CDD:275380	9/22 (41%)
		leucine-rich repeat	161..184	CDD:275380	6/22 (27%)
		leucine-rich repeat	185..209	CDD:275380	5/23 (22%)
		leucine-rich repeat	210..231	CDD:275380	4/20 (20%)
conv	NP_001286416.1	leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	150..175	CDD:275380
		leucine-rich repeat	176..199	CDD:275380	1/1 (100%)
		LRR_8	198..258	CDD:290566	18/59 (31%)
		leucine-rich repeat	200..223	CDD:275380	11/22 (50%)
		LRR_RI	201..545	CDD:238064	89/366 (24%)
		leucine-rich repeat	224..271	CDD:275380	10/46 (22%)
		LRR_8	245..306	CDD:290566	21/60 (35%)
		leucine-rich repeat	272..295	CDD:275380	9/22 (41%)
		LRR_8	296..354	CDD:290566	12/58 (21%)
		leucine-rich repeat	296..319	CDD:275380	6/22 (27%)
		LRR_8	322..401	CDD:290566	18/110 (16%)
		leucine-rich repeat	322..343	CDD:275380	5/21 (24%)
		leucine-rich repeat	344..367	CDD:275380	5/22 (23%)
		leucine-rich repeat	371..390	CDD:275380	5/35 (14%)
		leucine-rich repeat	391..414	CDD:275380	7/36 (19%)
		leucine-rich repeat	416..438	CDD:275380	6/23 (26%)
		LRR_8	437..495	CDD:290566	14/57 (25%)
		leucine-rich repeat	439..462	CDD:275380	6/22 (27%)
		leucine-rich repeat	463..486	CDD:275380	5/22 (23%)
		LRR_RI	486..738	CDD:238064	11/47 (23%)
		LRR_8	486..545	CDD:290566	11/47 (23%)
		leucine-rich repeat	487..510	CDD:275380	4/25 (16%)
		leucine-rich repeat	511..534	CDD:275380	6/19 (32%)
		leucine-rich repeat	535..554	CDD:275380
		LRR_8	554..614	CDD:290566
		leucine-rich repeat	555..578	CDD:275380
		leucine-rich repeat	579..603	CDD:275380
		leucine-rich repeat	604..627	CDD:275380
		LRR_8	626..710	CDD:290566
		leucine-rich repeat	628..649	CDD:275380
		leucine-rich repeat	652..672	CDD:275380
		LRR_8	698..765	CDD:290566
		leucine-rich repeat	700..726	CDD:275380
		leucine-rich repeat	727..745	CDD:275380
		LRR_8	777..839	CDD:290566
		leucine-rich repeat	779..802	CDD:275380
		leucine-rich repeat	829..852	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45617
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010