DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5810 and CG18480

DIOPT Version :9

Sequence 1:	NP_650952.2	Gene:	CG5810 / 42513	FlyBaseID:	FBgn0038866	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001285960.1	Gene:	CG18480 / 34920	FlyBaseID:	FBgn0028518	Length:	550	Species:	Drosophila melanogaster

Alignment Length:	273	Identity:	60/273 - (21%)
Similarity:	102/273 - (37%)	Gaps:	44/273 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ATCESQKLEEIAIDSLDCRENTCTNLKYPSASAVAYFSENVTKHLRKYETLVLHSSDLANLPRKI 82
            |.|.:::|....|:.....|  ..:|.|...:.:...|...|.||.   .|.|..:.:..|....
  Fly    58 AVCSAKRLISANIEIPTTVE--LLDLSYNDITTIDDDSFKTTIHLL---NLTLAHNAIHTLYGDA 117

  Fly    83 FLNLPQLVEFHVLECELQQIESVCFDGAKNLKRLNFGGNALRVLDSNTFELATQLEELNLSDNQL 147
            |:.|.:|....:....|:||:....:....|..||..||.|..|.......:..|..|||.::|:
  Fly   118 FVELTRLRYLDLSYNRLEQIDEHILESNNQLIHLNLEGNKLSTLGKGPILRSPSLRSLNLRNSQV 182

  Fly   148 EDLPTTIFRPLKNLQKINLSNNRLITLSQHIFSQLGSLKSINVDSNQLVELPGELFRDQRKHLSE 212
            ..|.|.:...|..|::::|:.|.|:|||...|....:|.|:||:.|
  Fly   183 NQLGTQLLSALPQLRQLDLAQNLLLTLSPGDFHAPRNLASLNVEEN------------------- 228

  Fly   213 FSAQSNQLVRIPFNIFREIDHLSLSFNPQLRRLHLS-AKINELEATNCDLESVELDGRVIGVQLE 276
                       |||..|.:..::.....:...:.:| ....|::....|.|:|....:
  Fly   229 -----------PFNCDRALAKVATGLRQRGVAIFMSNCMEEEVQDHQDDAEAVNFPNK------- 275

  Fly   277 ANPKLHELKISQP 289
             |.|...::..:|
  Fly   276 -NEKFESMEYLEP 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5810	NP_650952.2	leucine-rich repeat	65..88	CDD:275380	5/22 (23%)
		LRR_8	87..147	CDD:290566	15/59 (25%)
		leucine-rich repeat	89..112	CDD:275380	4/22 (18%)
		leucine-rich repeat	113..136	CDD:275380	7/22 (32%)
		LRR_8	135..195	CDD:290566	21/59 (36%)
		LRR_4	135..175	CDD:289563	13/39 (33%)
		leucine-rich repeat	137..160	CDD:275380	8/22 (36%)
		leucine-rich repeat	161..184	CDD:275380	8/22 (36%)
		leucine-rich repeat	185..209	CDD:275380	5/23 (22%)
		leucine-rich repeat	210..231	CDD:275380	4/20 (20%)
CG18480	NP_001285960.1	LRR_8	74..134	CDD:290566	13/64 (20%)
		LRR_RI	<76..230	CDD:238064	44/188 (23%)
		leucine-rich repeat	76..99	CDD:275380	5/24 (21%)
		leucine-rich repeat	100..123	CDD:275380	6/25 (24%)
		LRR_8	122..182	CDD:290566	15/59 (25%)
		leucine-rich repeat	124..147	CDD:275380	4/22 (18%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		LRR_8	170..230	CDD:290566	21/89 (24%)
		leucine-rich repeat	172..195	CDD:275380	8/22 (36%)
		leucine-rich repeat	196..219	CDD:275380	8/22 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930