DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5810 and kek5

DIOPT Version :9

Sequence 1:	NP_650952.2	Gene:	CG5810 / 42513	FlyBaseID:	FBgn0038866	Length:	428	Species:	Drosophila melanogaster
Sequence 2:	NP_001245746.1	Gene:	kek5 / 32930	FlyBaseID:	FBgn0031016	Length:	931	Species:	Drosophila melanogaster

Alignment Length:	273	Identity:	71/273 - (26%)
Similarity:	121/273 - (44%)	Gaps:	56/273 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 SLDCRENTCTNLKYPSAS--AVAYFSENVTKHLRKYETLVLHSSDLANLP--RKIFLNLPQLVEF 92
            |.||:....|.:....::  .|..|:.|....||:.|.|      ||.||  .||||.
  Fly    56 SADCKNKALTKIPQDMSNEMQVLDFAHNQIPELRREEFL------LAGLPNVHKIFLR------- 107

  Fly    93 HVLECELQQIESVCFDGAKNLKRLNFGGNALRVLDSNTFELATQLEELNLSDNQLEDLPTTIFRP 157
               .|.:|::....|.|...|..|:..||.:|.|...||....:|..:.:::|::|.||..:|..
  Fly   108 ---NCTIQEVHREAFKGLHILIELDLSGNRIRELHPGTFAGLEKLRNVIINNNEIEVLPNHLFVN 169

  Fly   158 LKNLQKINLSNNRLITLSQHIFSQLGSLKSINVDSNQLVELPGELFRDQRK--HLS--------- 211
            |..|.:|...||||..:..|:|:...:|.:|:::.|:|..|..|.|:|.:|  |||
  Fly   170 LSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNRLSHLHKETFKDLQKLMHLSLQGNAWNCS 234

  Fly   212 -------EFSAQSNQLVRIPFN----------IFREIDHLSLSFNPQLRRLHLSAKINELEATNC 259
                   :| |.|.:|...|.:          ::.|:...:.:..|::    |.:..:.:||.:
  Fly   235 CELQDFRDF-AISKRLYTPPTDCQEPPQLRGKLWSEVPSENFACRPRI----LGSVRSFIEANH- 293

  Fly   260 DLESVELDGRVIG 272
              :::.|..|::|
  Fly   294 --DNISLPCRIVG 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5810	NP_650952.2	leucine-rich repeat	65..88	CDD:275380	10/24 (42%)
		LRR_8	87..147	CDD:290566	14/59 (24%)
		leucine-rich repeat	89..112	CDD:275380	4/22 (18%)
		leucine-rich repeat	113..136	CDD:275380	8/22 (36%)
		LRR_8	135..195	CDD:290566	18/59 (31%)
		LRR_4	135..175	CDD:289563	13/39 (33%)
		leucine-rich repeat	137..160	CDD:275380	7/22 (32%)
		leucine-rich repeat	161..184	CDD:275380	8/22 (36%)
		leucine-rich repeat	185..209	CDD:275380	9/25 (36%)
		leucine-rich repeat	210..231	CDD:275380	7/46 (15%)
kek5	NP_001245746.1	LRR_RI	<76..160	CDD:238064	29/99 (29%)
		leucine-rich repeat	76..100	CDD:275380	10/29 (34%)
		LRR_8	99..159	CDD:290566	19/69 (28%)
		leucine-rich repeat	101..124	CDD:275380	8/32 (25%)
		LRR	122..145	CDD:197688	8/22 (36%)
		leucine-rich repeat	125..148	CDD:275380	8/22 (36%)
		LRR_8	148..207	CDD:290566	18/58 (31%)
		leucine-rich repeat	149..172	CDD:275380	7/22 (32%)
		leucine-rich repeat	173..196	CDD:275380	8/22 (36%)
		LRR_8	197..>229	CDD:290566	12/31 (39%)
		leucine-rich repeat	197..220	CDD:275380	8/22 (36%)
		LRRCT	229..277	CDD:214507	6/48 (13%)
		Ig	296..376	CDD:143165	3/9 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453621
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930