Protein Alignment CG5810 and lron-4

DIOPT Version :10

• Sequence 1: NP_650952.2
• Gene: CG5810 / 42513
• FlyBaseID: FBgn0038866
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_001309442.1
• Gene: lron-4 / 183375
• WormBaseID: WBGene00008051
• Length: 633
• Species: Caenorhabditis elegans
• Alignment Length: 345
• Identity: 79/345 - (22%)
• Similarity: 141/345 - (40%)
• Gaps: 71/345 - (20%)

  Fly    44 KYPSASAVAY----------FSENVTKHLR-------------------KYETLVLHSSDLANLP 79
            |.||..:::.          ..|.:|::||                   :.:.|...||...|:.
 Worm   270 KIPSLKSLSLSVIEITGKEDIPEGMTRNLRSIGFYDVKMNSIPNWIKTDQIQFLEFQSSISDNVD 334

  Fly    80 RKIFLNLPQLVEFHVLECELQQIESVCFDGAKNLKRLNFGGNALRVLDSNTFELATQLEELNLSD 144
            ......||.|..|.:.|..|..|:|.....:..|..|....|::..:.:..|:..|:|:.|||:.
 Worm   335 MSALDELPTLEHFLLTESSLTSIKSPFLSKSSKLISLTLQCNSISSIAAGAFDHFTELQFLNLAG 399

  Fly   145 NQLEDLPTTIFRPLKNLQKINL-----SNNRLITLSQHIFSQLGSLKSINVDSNQ----LVELPG 200
            |::..||:.:...|.||..::|     |:|.:.|     :::|.....||..::.    |.::|
 Worm   400 NRIASLPSNLLLNLNNLIVLDLKALDNSSNTIGT-----YNELSMQCQINQKASTVPVILDKMP- 458

  Fly   201 ELFRDQRKHLSEFSAQSNQLV--RIPFNIFREIDHLSLSFNPQLRRLHLSAKINELEATNCDLES 263
            ::.:.::....|...|.|.:.  :.....|:.::.|:|. |..|    |||:...|| |.|:|..
 Worm   459 DVSKPEKLVALEIRGQENIMKNDKSFLKNFKNLEILNLG-NLGL----LSAQNLSLE-TLCNLID 517

  Fly   264 VELDGRV------IGVQLEANPKLHELKISQPQDLEHLYLANTNLYRLDFLSKASKL-----VDL 317
            :.|.|..      |...|..|..|..|::.||..:..  :.|:   .:.|:..||::     :.|
 Worm   518 LNLVGNPLSDKDWISEDLFVNLNLQRLRMGQPSSMTS--IPNS---LVAFMRTASQIMYSTPISL 577

  Fly   318 DVTDIVNL---ADLPKITSA 334
            :..||...   .|..:|:||
 Worm   578 NSVDIYKRKIGCDYDRISSA 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5810	NP_650952.2	LRR	<61..353	CDD:443914	74/318 (23%)
		leucine-rich repeat	65..88	CDD:275380	5/22 (23%)
		leucine-rich repeat	89..112	CDD:275380	6/22 (27%)
		leucine-rich repeat	113..136	CDD:275380	4/22 (18%)
		leucine-rich repeat	137..160	CDD:275380	8/22 (36%)
		leucine-rich repeat	161..184	CDD:275380	6/27 (22%)
		leucine-rich repeat	185..209	CDD:275380	4/27 (15%)
		leucine-rich repeat	210..231	CDD:275380	4/22 (18%)
lron-4	NP_001309442.1	LRR	<266..>404	CDD:443914	29/133 (22%)
		leucine-rich repeat	274..300	CDD:275378	3/25 (12%)
		leucine-rich repeat	301..343	CDD:275378	5/41 (12%)
		LRR_8	342..402	CDD:404697	17/59 (29%)
		leucine-rich repeat	344..367	CDD:275378	6/22 (27%)
		leucine-rich repeat	368..391	CDD:275378	4/22 (18%)
		leucine-rich repeat	392..404	CDD:275378	5/11 (45%)