DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment cDIP and CLV2

DIOPT Version :9

Sequence 1:NP_650951.1 Gene:cDIP / 42512 FlyBaseID:FBgn0038865 Length:554 Species:Drosophila melanogaster
Sequence 2:NP_176717.1 Gene:CLV2 / 842849 AraportID:AT1G65380 Length:720 Species:Arabidopsis thaliana


Alignment Length:508 Identity:101/508 - (19%)
Similarity:179/508 - (35%) Gaps:206/508 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 LPTEVRIAEDGTTYEVGDEEHSRTLIFENCTFTNF---------------PLRLFYTLEVSELDM 123
            ||:  ||:|  ||.::|       |:..:.:..:|               .|||.:.|...::..
plant   304 LPS--RISE--TTEKLG-------LVLLDLSHNSFSGDIPLRITELKSLQALRLSHNLLTGDIPA 357

  Fly   124 RGCGIRFIYWENFS------------IGADKLVILLLSDNHIEVLPTKTFRGAGNLEFIFLNRNK 176
            |...:.::...:.|            :|..:|:.|::|:|::.                      
plant   358 RIGNLTYLQVIDLSHNALTGSIPLNIVGCFQLLALMISNNNLS---------------------- 400

  Fly   177 LGKLQAGAFDNLLKLQYLDLTENRLEALAADVFAGLKSLRHVGLAGNQLTTIESDLFAHNPDLLS 241
             |::|. ..|.|..|:.||::.|.:........||||||..|.::.|.|:...::......:|..
plant   401 -GEIQP-ELDALDSLKILDISNNHISGEIPLTLAGLKSLEIVDISSNNLSGNLNEAITKWSNLKY 463

  Fly   242 VAMQNNRLR-EVGEYAFRSRGRHHQMQYVDLSNN------PELVVLLLNINAT------------ 287
            :::..|:.. .:..:.|    :..::|.:|.|:|      |:     .|:|:|            
plant   464 LSLARNKFSGTLPSWLF----KFDKIQMIDYSSNRFSWFIPD-----DNLNSTRFKDFQTGGGEG 519

  Fly   288 ----------NLTARNCSLDRV----NLYGSVTNVDLSDN----RVRELYFPASEALEHLVLRNN 334
                      .::|...:.|.:    ||. |:..:|||||    .:.|..| ..:.:|:|.|..|
plant   520 FAEPPGKVEIKISAAVVAKDELSFSYNLL-SMVGIDLSDNLLHGEIPEALF-RQKNIEYLNLSYN 582

  Fly   335 SLV-QLASLSRVPRLRHLDVADNPNLGQLPDGWRTPHLEMLVLRNTGQMELPLEALQGMQNLQKL 398
            .|. ||..|.::|||:.||::.|...||             |:.|       :.|..|:      
plant   583 FLEGQLPRLEKLPRLKALDLSHNSLSGQ-------------VIGN-------ISAPPGL------ 621

  Fly   399 DISGNNLTEIDPSAFPTLTQLTHFYIHGNNWNCFSLRNIMDVLIRANGIAYTVDNYDPDFPGEYF 463
                            ||..|:|        ||||                              
plant   622 ----------------TLLNLSH--------NCFS------------------------------ 632

  Fly   464 HGIACMYRLPEKEGVDS-----SSSSEISASVESSPITSSSDPSEVDKLRDEL 511
             ||     :.||||:..     :.:.|:......    |..||:.:|..::|:
plant   633 -GI-----ITEKEGLGKFPGALAGNPELCVETPG----SKCDPANIDASQEEI 675

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cDIPNP_650951.1 leucine-rich repeat 118..142 CDD:275380 3/35 (9%)
LRR_RI 143..407 CDD:238064 64/301 (21%)
leucine-rich repeat 143..166 CDD:275380 4/22 (18%)
LRR_8 166..225 CDD:290566 16/58 (28%)
leucine-rich repeat 167..190 CDD:275380 4/22 (18%)
leucine-rich repeat 191..214 CDD:275380 7/22 (32%)
leucine-rich repeat 215..238 CDD:275380 4/22 (18%)
leucine-rich repeat 239..265 CDD:275380 3/26 (12%)
leucine-rich repeat 266..325 CDD:275380 20/94 (21%)
LRR_8 304..357 CDD:290566 21/57 (37%)
leucine-rich repeat 326..347 CDD:275380 8/21 (38%)
leucine-rich repeat 348..394 CDD:275380 10/45 (22%)
LRR_8 369..428 CDD:290566 8/58 (14%)
LRR_4 393..433 CDD:289563 6/39 (15%)
leucine-rich repeat 395..418 CDD:275380 2/22 (9%)
CLV2NP_176717.1 PLN00113 38..>665 CDD:215061 97/496 (20%)
leucine-rich repeat 123..146 CDD:275380
leucine-rich repeat 147..204 CDD:275380
leucine-rich repeat 218..241 CDD:275380
leucine-rich repeat 242..265 CDD:275380
leucine-rich repeat 266..289 CDD:275380
leucine-rich repeat 290..313 CDD:275380 6/12 (50%)
leucine-rich repeat 317..340 CDD:275380 2/22 (9%)
leucine-rich repeat 341..364 CDD:275380 5/22 (23%)
leucine-rich repeat 365..388 CDD:275380 2/22 (9%)
leucine-rich repeat 389..412 CDD:275380 8/46 (17%)
leucine-rich repeat 413..436 CDD:275380 7/22 (32%)
leucine-rich repeat 437..460 CDD:275380 4/22 (18%)
leucine-rich repeat 461..484 CDD:275380 3/26 (12%)
leucine-rich repeat 550..573 CDD:275380 7/23 (30%)
leucine-rich repeat 574..596 CDD:275380 8/21 (38%)
leucine-rich repeat 621..653 CDD:275380 14/97 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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