DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cDIP and AT5G23400

DIOPT Version :9

Sequence 1:	NP_650951.1	Gene:	cDIP / 42512	FlyBaseID:	FBgn0038865	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_197731.1	Gene:	AT5G23400 / 832405	AraportID:	AT5G23400	Length:	589	Species:	Arabidopsis thaliana

Alignment Length:	439	Identity:	104/439 - (23%)
Similarity:	168/439 - (38%)	Gaps:	122/439 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 LVILLLSDNHIEVLPTKTFRGAGNLEFIFLNRNKLGKLQAGAFDNLLKLQYLDLTENRLEA---- 203
            |.||.|:.|....|...:|.....|..:.|.||.........|.|||||:.|||:.|.|..
plant   158 LEILSLAGNRFSGLVPASFGSLRRLTTMNLARNSFSGPIPVTFKNLLKLENLDLSSNLLSGPIPD 222

  Fly   204 ------------LAADVFAG--------LKSLRHVGLAGNQLTTIESDLFAHNPDLLSVAMQNNR 248
                        |:::.|:|        |:.|:.:.|..|.||...||.|::...|.|:.:..|:
plant   223 FIGQFQNLTNLYLSSNRFSGVLPVSVYSLRKLQTMSLERNGLTGPLSDRFSYLKSLTSLQLSGNK 287

  Fly   249 LREVGEYAFRSRGRHHQMQYVDLSNN--------------PELVVLLLNINATNLTA-----RNC 294
            .  :|.......|..: :..::||.|              |.|:.:.|:.|..||.|     |:.
plant   288 F--IGHIPASITGLQN-LWSLNLSRNLFSDPLPVVGARGFPSLLSIDLSYNNLNLGAIPSWIRDK 349

  Fly   295 SLDRVNLYG--------------SVTNVDLSDN-----------------RVR----ELYFPAS- 323
            .|..:||.|              ::|::|||||                 :|:    :|.|..|
plant   350 QLSDINLAGCKLRGTFPKLTRPTTLTSLDLSDNFLTGDVSAFLTSLTNVQKVKLSKNQLRFDLSK 414

  Fly   324 ----EALEHLVLRNN----SLVQLASLSRVPRLRHLDVADNPNLGQLPDGWRTPHLEMLVL---R 377
                |.:..:.|.:|    ||..|.:......|..:.:.:|...|::||...:.:|::|.:   :
plant   415 LKLPEGVASIDLSSNLVTGSLSSLINNKTSSFLEEIHLTNNQISGRIPDFGESLNLKVLNIGSNK 479

  Fly   378 NTGQMELPLEALQGMQNLQKLDISGNNLTEIDPSAFPTLTQLTHFYIHGNNW------------- 429
            .:||:.   .::..:..|.:||||.|::|...|.|...|.||        .|
plant   480 ISGQIP---SSISNLVELVRLDISRNHITGGIPQAIGQLAQL--------KWLDLSINALTGRIP 533

  Fly   430 -NCFSLRNIMDVLIRANGIAYTVDNYDP--DFP-GEYFHGIA-CMYRLP 473
             :..:::.|.....|||.:...:....|  .|| ..|.|.:. |...||
plant   534 DSLLNIKTIKHASFRANRLCGQIPQGRPFNIFPAAAYLHNLCLCGKPLP 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cDIP	NP_650951.1	leucine-rich repeat	118..142	CDD:275380
		LRR_RI	143..407	CDD:238064	85/353 (24%)
		leucine-rich repeat	143..166	CDD:275380	7/22 (32%)
		LRR_8	166..225	CDD:290566	22/82 (27%)
		leucine-rich repeat	167..190	CDD:275380	7/22 (32%)
		leucine-rich repeat	191..214	CDD:275380	10/46 (22%)
		leucine-rich repeat	215..238	CDD:275380	8/22 (36%)
		leucine-rich repeat	239..265	CDD:275380	5/25 (20%)
		leucine-rich repeat	266..325	CDD:275380	25/117 (21%)
		LRR_8	304..357	CDD:290566	17/82 (21%)
		leucine-rich repeat	326..347	CDD:275380	5/24 (21%)
		leucine-rich repeat	348..394	CDD:275380	9/48 (19%)
		LRR_8	369..428	CDD:290566	16/61 (26%)
		LRR_4	393..433	CDD:289563	13/53 (25%)
		leucine-rich repeat	395..418	CDD:275380	10/22 (45%)
AT5G23400	NP_197731.1	PLN00113	39..>557	CDD:215061	96/412 (23%)
		leucine-rich repeat	109..133	CDD:275380
		leucine-rich repeat	134..157	CDD:275380
		leucine-rich repeat	158..181	CDD:275380	7/22 (32%)
		leucine-rich repeat	182..205	CDD:275380	7/22 (32%)
		leucine-rich repeat	206..229	CDD:275380	6/22 (27%)
		leucine-rich repeat	230..253	CDD:275380	4/22 (18%)
		leucine-rich repeat	254..277	CDD:275380	8/22 (36%)
		leucine-rich repeat	278..301	CDD:275380	5/24 (21%)
		leucine-rich repeat	302..326	CDD:275380	3/23 (13%)
		leucine-rich repeat	374..397	CDD:275380	6/22 (27%)
		leucine-rich repeat	398..440	CDD:275380	10/41 (24%)
		leucine-rich repeat	447..469	CDD:275380	5/21 (24%)
		leucine-rich repeat	470..493	CDD:275380	4/25 (16%)
		leucine-rich repeat	494..517	CDD:275380	10/22 (45%)
		leucine-rich repeat	518..536	CDD:275380	2/25 (8%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910