DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cDIP and AT4G13820

DIOPT Version :9

Sequence 1:	NP_650951.1	Gene:	cDIP / 42512	FlyBaseID:	FBgn0038865	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_193118.2	Gene:	AT4G13820 / 827016	AraportID:	AT4G13820	Length:	719	Species:	Arabidopsis thaliana

Alignment Length:	604	Identity:	130/604 - (21%)
Similarity:	218/604 - (36%)	Gaps:	167/604 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LCSYLLISLAATATTDEDADADVDSGSSRIVLVSSLEGHCQTEGKVTSCRGFEFAGEDEK-ATFD 73
            ||  |::||:                :|::||.|.::..|:               :|:| |..:
plant     8 LC--LILSLS----------------NSKLVLASHVKHLCR---------------QDQKNALLE 39

  Fly    74 LPTEVRIAEDGTTYEVGDEEHSRTLIFENC----------------------TFTNFPLR----L 112
            ...|..:.|..:...||.::..:.....:|                      :|.|.|||    |
plant    40 FKNEFYVHEFNSNGIVGVKKTEKWRNNTDCCSWDGISCDPKTGKVVELDLMNSFLNGPLRYDSSL 104

  Fly   113 FYTLEVSELDMRGCGIRFIYWENF------SIGADK-LVILLLSD-NHIEVLPTKTFRGAGNLEF 169
            |....:..||:..        .||      |||:.| |.:|.|.| |....:|:    ..|||.:
plant   105 FRLQHLHNLDLGS--------NNFSGILPDSIGSLKYLRVLSLGDCNLFGKIPS----SLGNLTY 157

  Fly   170 I---------FLNR--------NKLGKLQAGAFD----------NLLKLQYLDLTENRLEALAAD 207
            :         |...        |||.:|..|:..          ||.:|..:||..|:...:...
plant   158 LTNLDLSVNDFTGELPDSMGHLNKLTELHLGSAKLSGNFPSMLLNLSELTLIDLGSNQFGGMLPS 222

  Fly   208 VFAGLKSLRHVGLAGNQLT-TIESDLFAHNPDLLSVAMQNNRLREVGEYAFRSRGRHHQMQYVDL 271
            ..:.|..|.:.|:..|..: :|.|.||. .|.|.|:.:..|...  |...|.:......:..:.|
plant   223 NMSSLSKLVYFGIDRNSFSGSIPSSLFM-LPSLTSLVLGRNDFN--GPLDFGNISSPSNLGVLSL 284

  Fly   272 SNN------PELVVLLLNINATNLTARNCSLDRVNL-----YGSVTNVDLSDNRVREL----YFP 321
            ..|      ||.:..|:.:...:|:..|.....|:.     ..|:|.:|||....|.:    .|.
plant   285 LENNFNGPIPESISKLVGLFYLDLSLWNTKRGMVDFNTFLHLKSLTFLDLSYINTRSMVDISIFS 349

  Fly   322 ASEALEHLVLRNNSLVQLASLS-------------RVPR----------LRHLDVADNPNLGQLP 363
            ...:|.:|.|...:|...::||             .:|.          |.:||::.|...||:|
plant   350 PLLSLGYLDLSGINLKISSTLSLPSPMGTLILSSCNIPEFPNFLENQTTLYYLDISANKIGGQVP 414

  Fly   364 DG-WRTPHLEML-VLRNT-GQMELPLEALQGMQNLQKLDISGNNLTEIDPSAFPTLTQLTHFYIH 425
            .. |..|.|:.: :.:|: ...|.|.:.:|....|..||||.|  |..||  ||.|...|..::.
plant   415 QWLWSLPELQYVNISQNSFSGFEGPADVIQRCGELLMLDISSN--TFQDP--FPLLPNSTTIFLG 475

  Fly   426 GNNWNCFSLRNIMDVLIRANGIAYTVDNYDPDFPG--EYFHGIACMYRL---------PEKEGVD 479
            .:|.....:...:..|:..:.:..:.:|::...|.  |.|:....:..|         ||:...|
plant   476 SDNRFSGEIPKTICKLVSLDTLVLSNNNFNGSIPRCFEKFNTTLSVLHLRNNNLSGEFPEESISD 540

  Fly   480 SSSSSEISASVESSPITSS 498
            ...|.::..:..|..:..|
plant   541 HLRSLDVGRNRLSGELPKS 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cDIP	NP_650951.1	leucine-rich repeat	118..142	CDD:275380	7/29 (24%)
		LRR_RI	143..407	CDD:238064	77/333 (23%)
		leucine-rich repeat	143..166	CDD:275380	6/23 (26%)
		LRR_8	166..225	CDD:290566	18/85 (21%)
		leucine-rich repeat	167..190	CDD:275380	9/49 (18%)
		leucine-rich repeat	191..214	CDD:275380	5/22 (23%)
		leucine-rich repeat	215..238	CDD:275380	7/23 (30%)
		leucine-rich repeat	239..265	CDD:275380	5/25 (20%)
		leucine-rich repeat	266..325	CDD:275380	15/73 (21%)
		LRR_8	304..357	CDD:290566	17/79 (22%)
		leucine-rich repeat	326..347	CDD:275380	6/33 (18%)
		leucine-rich repeat	348..394	CDD:275380	14/48 (29%)
		LRR_8	369..428	CDD:290566	19/60 (32%)
		LRR_4	393..433	CDD:289563	14/39 (36%)
		leucine-rich repeat	395..418	CDD:275380	12/22 (55%)
AT4G13820	NP_193118.2	LRRNT_2	31..78	CDD:285463	8/46 (17%)
		LRR_RI	<79..216	CDD:238064	36/148 (24%)
		LRR_8	109..168	CDD:290566	17/70 (24%)
		leucine-rich repeat	110..133	CDD:275380	7/30 (23%)
		leucine-rich repeat	134..157	CDD:275380	9/26 (35%)
		leucine-rich repeat	158..181	CDD:275380	1/22 (5%)
		leucine-rich repeat	182..205	CDD:275380	5/22 (23%)
		leucine-rich repeat	206..229	CDD:275380	5/22 (23%)
		leucine-rich repeat	230..253	CDD:275380	7/23 (30%)
		leucine-rich repeat	254..278	CDD:275380	5/25 (20%)
		leucine-rich repeat	279..302	CDD:275380	5/22 (23%)
		leucine-rich repeat	303..328	CDD:275380	3/24 (13%)
		leucine-rich repeat	329..353	CDD:275380	6/23 (26%)
		leucine-rich repeat	354..372	CDD:275380	5/17 (29%)
		leucine-rich repeat	378..398	CDD:275380	1/19 (5%)
		leucine-rich repeat	399..422	CDD:275380	8/22 (36%)
		LRR_RI	419..>624	CDD:238064	32/145 (22%)
		leucine-rich repeat	423..448	CDD:275380	5/24 (21%)
		leucine-rich repeat	469..493	CDD:275380	3/23 (13%)
		leucine-rich repeat	494..518	CDD:275380	4/23 (17%)
		leucine-rich repeat	519..541	CDD:275380	3/21 (14%)
		leucine-rich repeat	542..565	CDD:275380	3/18 (17%)
		leucine-rich repeat	566..615	CDD:275380
		leucine-rich repeat	616..634	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000