DRSC/TRiP Functional Genomics Resources

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Protein Alignment cDIP and Lrrc15

DIOPT Version :9

Sequence 1:NP_650951.1 Gene:cDIP / 42512 FlyBaseID:FBgn0038865 Length:554 Species:Drosophila melanogaster
Sequence 2:NP_083249.1 Gene:Lrrc15 / 74488 MGIID:1921738 Length:579 Species:Mus musculus


Alignment Length:345 Identity:93/345 - (26%)
Similarity:148/345 - (42%) Gaps:38/345 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   146 LLLSDNHIEVLPTKTFRGAGNLEFIFLNRNKLGKLQAGAFDNLLKLQYLDLTENRLEALAADVFA 210
            |.:.:.||..||...|.....|..:.:.:|:|..:..|||.||..|::|.|..|:|:.|...:|.
Mouse    58 LQILNTHITELPEDKFLNISALIALKMEKNELANIMPGAFRNLGSLRHLSLANNKLKNLPVRLFQ 122

  Fly   211 GLKSLRHVGLAGNQLTTIESDLFAHNPDLLSVAMQNNRLREVGEYAFRSRGRHH--QMQYVDLSN 273
            .:.:|..:.|:.|||..|:...|:...:|..:.:..|.|..:.|..|     .|  .:..::|.|
Mouse   123 DVNNLETLLLSNNQLVQIQPAQFSQFSNLKELQLYGNNLEYIPEGVF-----DHLVGLTKLNLGN 182

  Fly   274 N------PELVVLLLNINATNLTARNCS---LDRVNLYGSVTNVDLSDNRVREL---YFPASEAL 326
            |      |.:...|.|:....|.....|   :...:..|::..:.|.:|::..|   .|..:..|
Mouse   183 NGFTHLSPRVFQHLGNLQVLRLYENRLSDIPMGTFDALGNLQELALQENQIGTLSPGLFHNNRNL 247

  Fly   327 EHLVLRNNSLVQL--ASLSRVPRLRHLDVADNPNLGQLPDG--WRTPHLEMLVLRNTGQMELPLE 387
            :.|.|.||.:..|  ....::|.|..|.:..| :|.:|..|  ...|:|..|.|.|.....||..
Mouse   248 QRLYLSNNHISHLPPGIFMQLPHLNKLTLFGN-SLKELSPGVFGPMPNLRELWLYNNHITSLPDN 311

  Fly   388 ALQGMQNLQKLDISGNNLTEIDPSAFPTLTQLTHFYIHGN-----NWNCF-SLRNIMDVLIRANG 446
            |...:..||.|.:|.|.|:.|.|.||..||.|....:|.|     :.|.| ||.|:.:|.::.|.
Mouse   312 AFSHLNQLQVLILSHNQLSYISPGAFNGLTNLRELSLHTNALQDLDGNVFRSLANLRNVSLQNNR 376

  Fly   447 IAYTVDNYDPDFPGEYFHGI 466
            :.        ..||..|..:
Mouse   377 LR--------QLPGSIFANV 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cDIPNP_650951.1 leucine-rich repeat 118..142 CDD:275380
LRR_RI 143..407 CDD:238064 74/278 (27%)
leucine-rich repeat 143..166 CDD:275380 6/19 (32%)
LRR_8 166..225 CDD:290566 18/58 (31%)
leucine-rich repeat 167..190 CDD:275380 8/22 (36%)
leucine-rich repeat 191..214 CDD:275380 7/22 (32%)
leucine-rich repeat 215..238 CDD:275380 7/22 (32%)
leucine-rich repeat 239..265 CDD:275380 6/27 (22%)
leucine-rich repeat 266..325 CDD:275380 13/70 (19%)
LRR_8 304..357 CDD:290566 13/57 (23%)
leucine-rich repeat 326..347 CDD:275380 6/22 (27%)
leucine-rich repeat 348..394 CDD:275380 14/47 (30%)
LRR_8 369..428 CDD:290566 23/63 (37%)
LRR_4 393..433 CDD:289563 17/45 (38%)
leucine-rich repeat 395..418 CDD:275380 11/22 (50%)
Lrrc15NP_083249.1 LRR 1 54..75 6/16 (38%)
leucine-rich repeat 58..78 CDD:275380 6/19 (32%)
LRR 2 78..99 6/20 (30%)
PLN00113 82..>401 CDD:215061 86/321 (27%)
LRR 3 102..123 7/20 (35%)
leucine-rich repeat 103..126 CDD:275380 7/22 (32%)
LRR 4 126..147 7/20 (35%)
leucine-rich repeat 127..150 CDD:275380 7/22 (32%)
LRR 5 150..171 5/25 (20%)
leucine-rich repeat 151..174 CDD:275380 6/27 (22%)
LRR 6 174..195 4/20 (20%)
leucine-rich repeat 175..198 CDD:275380 5/22 (23%)
LRR 7 198..219 3/20 (15%)
leucine-rich repeat 199..222 CDD:275380 2/22 (9%)
LRR 8 222..243 4/20 (20%)
leucine-rich repeat 223..246 CDD:275380 4/22 (18%)
LRR 9 246..267 6/20 (30%)
leucine-rich repeat 247..270 CDD:275380 6/22 (27%)
LRR 10 270..291 6/21 (29%)
leucine-rich repeat 271..294 CDD:275380 6/23 (26%)
LRR 11 294..315 7/20 (35%)
leucine-rich repeat 295..318 CDD:275380 7/22 (32%)
LRR 12 318..339 10/20 (50%)
leucine-rich repeat 319..342 CDD:275380 11/22 (50%)
LRR 13 342..363 5/20 (25%)
leucine-rich repeat 343..364 CDD:275380 5/20 (25%)
LRR 14 366..387 6/28 (21%)
leucine-rich repeat 367..387 CDD:275380 5/27 (19%)
LRR 15 390..411
leucine-rich repeat 391..412 CDD:275380
LRRCT 423..>462 CDD:214507
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 476..509
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
32.870

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