back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cDIP and si:dkey-90m5.4

DIOPT Version :9

Sequence 1:	NP_650951.1	Gene:	cDIP / 42512	FlyBaseID:	FBgn0038865	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_001038237.1	Gene:	si:dkey-90m5.4 / 553466	ZFINID:	ZDB-GENE-041014-250	Length:	327	Species:	Danio rerio

Alignment Length:	338	Identity:	73/338 - (21%)
Similarity:	131/338 - (38%)	Gaps:	82/338 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 LKLQYLDLTENRLEALAADVFAGLKSLRHVGLAGNQLTTIESDLFAHNPDLLSVAMQNNRLREVG 253
            |.:|:.:||     .|.::....:..|..:.|.||:|:::.:|:......|.::.:.:|.|||:.
Zfish    60 LTIQFTNLT-----VLTSEHLRAVPLLEELHLPGNKLSSLPADILKDLKYLHTIDLTDNELRELP 119

  Fly   254 EYAFRSRGRHHQMQYVDLSNNPELVVLLLNINATNLTARNCSLDRVNLYGSVTNVDLSDNRVREL 318
            ||.||                                           :..:.|:.|.|||:..:
Zfish   120 EYVFR-------------------------------------------HAPLLNLVLKDNRISNI 141

  Fly   319 ---YFPASEALEHLVLRNNSLVQLASLSRVPRLRHLDV--ADNPNLGQLPDGWRTPH--LEMLVL 376
               :||.:..|..|.|..|.|::. .::::..||||.|  .....:.:||.|....|  ||.|.|
Zfish   142 HPDWFPNNSNLTWLDLSGNQLMKF-PMAQLQNLRHLKVLHLSQNKIEELPVGCLDAHTALERLYL 205

  Fly   377 RNTGQMELPLEALQGMQNLQKLDISGNNLTEIDPSAFPTLTQLTHFYIHGNNWNCFSLRNIMDVL 441
            .......|.::|..|..||..:.:..|.:..:.|:.|..|.:|.:..:..|... |....|:|
Zfish   206 DQNKIQTLDVKAFSGSTNLTHIFLQKNRIDSLPPTVFQELKRLEYVDLSDNRLQ-FLSPGILD-- 267

  Fly   442 IRANGIAYTVDNYDPDFPGEYFHGIACMYRLPEKEGVDSSSSSEISASVESSPITSSSDPSEVDK 506
            |..:.:..|.:.:..|...||      ::|....|            |::|.|..::.     :.
Zfish   268 INTSWVELTFNPWHCDAKIEY------LWRKITME------------SLQSEPKCAAP-----EN 309

  Fly   507 LRDELKAVVQHFD 519
            |:|.:.|.:...|
Zfish   310 LKDRVIATLTRKD 322

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.