DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment cDIP and atk

DIOPT Version :9

Sequence 1:NP_650951.1 Gene:cDIP / 42512 FlyBaseID:FBgn0038865 Length:554 Species:Drosophila melanogaster
Sequence 2:NP_001262113.1 Gene:atk / 40266 FlyBaseID:FBgn0036995 Length:1535 Species:Drosophila melanogaster


Alignment Length:555 Identity:138/555 - (24%)
Similarity:223/555 - (40%) Gaps:127/555 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 VRIAEDGTTYEVGD--EEH---SRTLIFENCTFTNFP-LRLFYTLE--------VSELDMRGCGI 128
            :.:.|||:..::.:  |.|   :|....:...|...| |:..|...        .|.|...|.|:
  Fly   270 ITVIEDGSFVDLPNLSELHLNDNRITELQYGAFLRTPQLKTIYLQNNLIRRIHPESLLQASGSGV 334

  Fly   129 RFIYWENFSIG-----------ADKLVILLLSDNHIEVLPTKTFRGAGNLEFIFLNRNKLGKLQA 182
            ..::..|..||           ..:|..|.:|.|.:..||....||.|.||.:.||.|.|..::.
  Fly   335 EAVHMYNNEIGHVEALRALLDALPRLRYLDMSGNLLSELPYGALRGHGTLEQLHLNHNHLRLIER 399

  Fly   183 GA------------------------FDNLLKLQYLDLTENRLEALAADVFAGLKSLRHVGLAGN 223
            .|                        |.||..|:.|||.:|:...:.:.:.|||.|||.:.|:.|
  Fly   400 DALMAMPALRELRMRNNSLSSDLPLPFWNLPGLKGLDLAQNQFARVDSQLLAGLPSLRRLDLSEN 464

  Fly   224 QLTTIESDLFAHNPDLLSVAMQNNRLREVG-------EYAFRSRGRHHQMQYVDLSNNPELV--V 279
            .|..:..:.|.|||.|.::.:.:|.|.::.       |..|.....::|::.| ::..|.:|  :
  Fly   465 GLIELAPNSFRHNPLLETLNISSNELTKIHSSTLIHLERLFEVDASYNQLKSV-IAGLPRIVERI 528

  Fly   280 LLLNINATNLTA---RNCSLDRVNLYGSVTNVDLSDNRVREL---YFPASEALEHLVLRNNSLVQ 338
            .|.....|:|.|   ::..|..:.:      :|||.||:.:|   .|..:..|..|.|..|.|.|
  Fly   529 SLKGNQITSLPAAASKDLQLPNLRM------LDLSQNRIEQLPRHGFQGAMELRVLSLAQNELRQ 587

  Fly   339 L--ASLSRVPRLRHLDVADNPNLGQLPDGWRTPHLEMLVLRNTGQMELPLEAL-----QGMQNLQ 396
            |  .|...:.||..|.:.:| .||:..:....|..|   |||.......|||:     .....|:
  Fly   588 LKDTSFIGIQRLELLHLQEN-QLGEADERALLPLAE---LRNLNLQSNKLEAITDNFFSNNSRLE 648

  Fly   397 KLDISGNNLTEIDPSAFPTLTQLTHFYIHGN-----NWNCFSLRNIMDVLIRANGIAYTVDNYDP 456
            :||:|.|.:..|.|:||.|...|.:..:.||     :....:|.|:.|:.:..|.|:    ....
  Fly   649 QLDLSRNLIRSISPTAFDTQRSLEYLDLSGNALLDISVGLGNLNNLRDIDLSYNQIS----RIQS 709

  Fly   457 DFPGEYFHGI--------------ACMYRLPEKEGVDSSSSSEISASVESSPITSSSDPSEVDKL 507
            |..|.:.:.:              .....||:.:.:| .||:|| .:||...:          |.
  Fly   710 DVIGGWRNVVEIRLSNNLIVELQQGTFRNLPKLQYLD-LSSNEI-RNVEPGAL----------KG 762

  Fly   508 RDELKAVVQHFDSKFDLIFSKLAQLNEQIQAFEVL 542
            .|||:        :|.|..:||.:|.:.:  ||.|
  Fly   763 LDELQ--------EFVLADNKLVELKDHV--FEEL 787

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cDIPNP_650951.1 leucine-rich repeat 118..142 CDD:275380 7/34 (21%)
LRR_RI 143..407 CDD:238064 85/309 (28%)
leucine-rich repeat 143..166 CDD:275380 8/22 (36%)
LRR_8 166..225 CDD:290566 23/82 (28%)
leucine-rich repeat 167..190 CDD:275380 10/46 (22%)
leucine-rich repeat 191..214 CDD:275380 8/22 (36%)
leucine-rich repeat 215..238 CDD:275380 8/22 (36%)
leucine-rich repeat 239..265 CDD:275380 5/32 (16%)
leucine-rich repeat 266..325 CDD:275380 15/66 (23%)
LRR_8 304..357 CDD:290566 18/57 (32%)
leucine-rich repeat 326..347 CDD:275380 8/22 (36%)
leucine-rich repeat 348..394 CDD:275380 13/50 (26%)
LRR_8 369..428 CDD:290566 21/68 (31%)
LRR_4 393..433 CDD:289563 13/44 (30%)
leucine-rich repeat 395..418 CDD:275380 10/22 (45%)
atkNP_001262113.1 leucine-rich repeat 69..89 CDD:275380
leucine-rich repeat 90..113 CDD:275380
leucine-rich repeat 115..138 CDD:275380
leucine-rich repeat 139..160 CDD:275380
leucine-rich repeat 161..184 CDD:275380
LRR_8 183..244 CDD:290566
leucine-rich repeat 185..209 CDD:275380
LRR_4 209..247 CDD:289563
leucine-rich repeat 210..233 CDD:275380
leucine-rich repeat 234..259 CDD:275380
LRR_RI 250..492 CDD:238064 57/221 (26%)
LRR_8 259..318 CDD:290566 10/47 (21%)
leucine-rich repeat 260..283 CDD:275380 3/12 (25%)
leucine-rich repeat 284..307 CDD:275380 4/22 (18%)
leucine-rich repeat 308..359 CDD:275380 9/50 (18%)
leucine-rich repeat 334..348 CDD:275378 3/13 (23%)
LRR_8 358..418 CDD:290566 16/59 (27%)
leucine-rich repeat 360..383 CDD:275380 8/22 (36%)
leucine-rich repeat 384..407 CDD:275380 7/22 (32%)
LRR_8 406..466 CDD:290566 16/59 (27%)
leucine-rich repeat 408..431 CDD:275380 3/22 (14%)
leucine-rich repeat 432..455 CDD:275380 8/22 (36%)
LRR_RI 447..705 CDD:238064 73/268 (27%)
LRR_8 454..514 CDD:290566 15/59 (25%)
leucine-rich repeat 456..476 CDD:275380 6/19 (32%)
leucine-rich repeat 480..501 CDD:275380 3/20 (15%)
leucine-rich repeat 505..517 CDD:275378 2/11 (18%)
leucine-rich repeat 525..550 CDD:275380 6/24 (25%)
LRR_8 549..609 CDD:290566 19/66 (29%)
leucine-rich repeat 551..574 CDD:275380 7/28 (25%)
leucine-rich repeat 575..598 CDD:275380 8/22 (36%)
leucine-rich repeat 599..622 CDD:275380 6/23 (26%)
LRR_8 622..681 CDD:290566 20/61 (33%)
leucine-rich repeat 623..646 CDD:275380 6/22 (27%)
LRR_RI 647..896 CDD:238064 41/167 (25%)
leucine-rich repeat 647..670 CDD:275380 10/22 (45%)
leucine-rich repeat 671..693 CDD:275380 4/21 (19%)
leucine-rich repeat 694..717 CDD:275380 5/26 (19%)
LRR_8 716..776 CDD:290566 15/79 (19%)
leucine-rich repeat 718..741 CDD:275380 1/22 (5%)
leucine-rich repeat 742..763 CDD:275380 8/32 (25%)
LRR_8 765..824 CDD:290566 10/33 (30%)
leucine-rich repeat 766..789 CDD:275380 9/32 (28%)
leucine-rich repeat 790..813 CDD:275380
leucine-rich repeat 814..835 CDD:275380
leucine-rich repeat 838..861 CDD:275380
LRR_8 862..921 CDD:290566
leucine-rich repeat 862..885 CDD:275380
leucine-rich repeat 886..906 CDD:275380
TPKR_C2 919..>946 CDD:301599
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

Return to query results.
Submit another query.