DRSC/TRiP Functional Genomics Resources

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Protein Alignment cDIP and kek5

DIOPT Version :9

Sequence 1:NP_650951.1 Gene:cDIP / 42512 FlyBaseID:FBgn0038865 Length:554 Species:Drosophila melanogaster
Sequence 2:NP_001245746.1 Gene:kek5 / 32930 FlyBaseID:FBgn0031016 Length:931 Species:Drosophila melanogaster


Alignment Length:278 Identity:75/278 - (26%)
Similarity:117/278 - (42%) Gaps:55/278 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   123 MRGCGIRFIYWENFSIGAD---------------KLVILLLSDNHIEVLPTKTFRGAG--NLEFI 170
            |:.||.....|.:....||               ::.:|..:.|.|..|..:.|..||  |:..|
  Fly    40 MQSCGTCHCQWNSGKKSADCKNKALTKIPQDMSNEMQVLDFAHNQIPELRREEFLLAGLPNVHKI 104

  Fly   171 FLNRNKLGKLQAGAFDNLLKLQYLDLTENRLEALAADVFAGLKSLRHVGLAGNQLTTIESDLFAH 235
            ||....:.::...||..|..|..|||:.||:..|....||||:.||:|.:..|::..:.:.||.:
  Fly   105 FLRNCTIQEVHREAFKGLHILIELDLSGNRIRELHPGTFAGLEKLRNVIINNNEIEVLPNHLFVN 169

  Fly   236 NPDLLSVAMQNNRLREVGEYAF------------RSRGRH-HQMQYVDLSNNPELVVLLLNINAT 287
            ...|..:..:|||||:|..:.|            ::|..| |:..:.||.   :|:.|.|..||.
  Fly   170 LSFLSRIEFRNNRLRQVQLHVFAGTMALSAISLEQNRLSHLHKETFKDLQ---KLMHLSLQGNAW 231

  Fly   288 NLTARNCSLDRVNLYGSVTNVDLSDNRV-RELYFPASEALEHLVLRNN--SLVQLASLSRVPRL- 348
            |.   :|.|.           |..|..: :.||.|.::..|...||..  |.|...:.:..||: 
  Fly   232 NC---SCELQ-----------DFRDFAISKRLYTPPTDCQEPPQLRGKLWSEVPSENFACRPRIL 282

  Fly   349 ---RHLDVADNPNLGQLP 363
               |....|::.|: .||
  Fly   283 GSVRSFIEANHDNI-SLP 299

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cDIPNP_650951.1 leucine-rich repeat 118..142 CDD:275380 6/33 (18%)
LRR_RI 143..407 CDD:238064 69/243 (28%)
leucine-rich repeat 143..166 CDD:275380 7/24 (29%)
LRR_8 166..225 CDD:290566 22/58 (38%)
leucine-rich repeat 167..190 CDD:275380 6/22 (27%)
leucine-rich repeat 191..214 CDD:275380 11/22 (50%)
leucine-rich repeat 215..238 CDD:275380 6/22 (27%)
leucine-rich repeat 239..265 CDD:275380 10/38 (26%)
leucine-rich repeat 266..325 CDD:275380 15/59 (25%)
LRR_8 304..357 CDD:290566 14/59 (24%)
leucine-rich repeat 326..347 CDD:275380 5/22 (23%)
leucine-rich repeat 348..394 CDD:275380 5/20 (25%)
LRR_8 369..428 CDD:290566
LRR_4 393..433 CDD:289563
leucine-rich repeat 395..418 CDD:275380
kek5NP_001245746.1 LRR_RI <76..160 CDD:238064 29/83 (35%)
leucine-rich repeat 76..100 CDD:275380 7/23 (30%)
LRR_8 99..159 CDD:290566 22/59 (37%)
leucine-rich repeat 101..124 CDD:275380 6/22 (27%)
LRR 122..145 CDD:197688 9/22 (41%)
leucine-rich repeat 125..148 CDD:275380 11/22 (50%)
LRR_8 148..207 CDD:290566 14/58 (24%)
leucine-rich repeat 149..172 CDD:275380 6/22 (27%)
leucine-rich repeat 173..196 CDD:275380 8/22 (36%)
LRR_8 197..>229 CDD:290566 8/34 (24%)
leucine-rich repeat 197..220 CDD:275380 5/25 (20%)
LRRCT 229..277 CDD:214507 15/61 (25%)
Ig 296..376 CDD:143165 2/5 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453740
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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