DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment cDIP and Cpn2

DIOPT Version :9

Sequence 1:NP_650951.1 Gene:cDIP / 42512 FlyBaseID:FBgn0038865 Length:554 Species:Drosophila melanogaster
Sequence 2:NP_001100555.1 Gene:Cpn2 / 303861 RGDID:1305170 Length:565 Species:Rattus norvegicus


Alignment Length:428 Identity:108/428 - (25%)
Similarity:166/428 - (38%) Gaps:108/428 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    58 CRGFE---FAGEDEKAT--FDLPTEVRIAEDGTTYEVGDEEHSRTLIFENCTFTNFPLRLFYTLE 117
            |..|:   |..:::.|.  .|:|:                 |...::|...:||....|.|    
  Rat    49 CDCFDRKIFCSDEQLAAIPLDIPS-----------------HVTDIVFVETSFTTVGTRAF---- 92

  Fly   118 VSELDMRGCGIRFIYWENFSIGADKLVILLLSDNHIEVLPTKTFRGAGNLEFIFLNRNKLGKLQA 182
                             :.|....|:|.|....:|:|   ...|.|...||.:.:..:....|.|
  Rat    93 -----------------SGSPNLTKVVFLNTRVHHLE---PDAFGGLPRLEDLEVTGSPFSNLSA 137

  Fly   183 GAFDNLLKLQYLDLTENRLEALAADVFAGLKSLRHVGLAGNQLTTIESDLFAHNPDLLSVAMQNN 247
            ..|.||..|..|.|..|||.||..|:|..:.:|..:.|.||||.|:...||.....|.::.:..|
  Rat   138 NIFSNLSSLGKLTLDFNRLAALPEDLFHHMDTLESLQLQGNQLQTLPGRLFQSLRYLRTLNLAQN 202

  Fly   248 RLREVGEYAFRSRGRHHQMQYVDLSNN-----PELVV--------LLLNINA-----TNLTARNC 294
            .|.::.:..|:|..   .:|.:.||:|     ||.|:        |.|:.||     .:|.:...
  Rat   203 LLTQLPKGMFQSLS---SLQILKLSDNMFARLPEGVLSNLGSLQELFLDSNAITELSPHLFSHLL 264

  Fly   295 SLDR------------VNLYGSVTN---VDLSDNRVREL---YFPASEALEHLVLRNNSL--VQL 339
            ||::            |:.:.|:.|   ::|.||.:|.|   .|..:..|.||.|..|.|  |..
  Rat   265 SLEKLWLQHNAISHLPVSAFSSLRNLTFLNLKDNALRTLPAGLFTHNPGLLHLSLSYNQLETVPE 329

  Fly   340 ASLSRVPRLRHLDVADNPNLGQLPDGWRTPHLEMLVLRNTGQM-ELPLEA----------LQGMQ 393
            .|.:.:.:|..|.::.|          ...||...|.||..|: :|.|::          ...:.
  Rat   330 GSFANLRKLASLTLSHN----------AITHLPENVFRNLEQLVKLSLDSNNLTVLHPTLFHNLS 384

  Fly   394 NLQKLDISGNNLTEIDPSAFPTLTQLTHFYIHGNNWNC 431
            .||.||:|.|.||.:....|.|...|.:..:.||.|.|
  Rat   385 KLQLLDLSRNQLTMLPGGIFDTNYDLFNLALLGNPWQC 422

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cDIPNP_650951.1 leucine-rich repeat 118..142 CDD:275380 1/23 (4%)
LRR_RI 143..407 CDD:238064 86/312 (28%)
leucine-rich repeat 143..166 CDD:275380 6/22 (27%)
LRR_8 166..225 CDD:290566 21/58 (36%)
leucine-rich repeat 167..190 CDD:275380 7/22 (32%)
leucine-rich repeat 191..214 CDD:275380 10/22 (45%)
leucine-rich repeat 215..238 CDD:275380 9/22 (41%)
leucine-rich repeat 239..265 CDD:275380 5/25 (20%)
leucine-rich repeat 266..325 CDD:275380 23/94 (24%)
LRR_8 304..357 CDD:290566 18/60 (30%)
leucine-rich repeat 326..347 CDD:275380 8/22 (36%)
leucine-rich repeat 348..394 CDD:275380 11/56 (20%)
LRR_8 369..428 CDD:290566 20/69 (29%)
LRR_4 393..433 CDD:289563 15/39 (38%)
leucine-rich repeat 395..418 CDD:275380 10/22 (45%)
Cpn2NP_001100555.1 LRRNT 44..75 CDD:214470 7/42 (17%)
leucine-rich repeat 77..97 CDD:275380 6/40 (15%)
LRR_8 96..156 CDD:290566 18/62 (29%)
leucine-rich repeat 122..145 CDD:275380 7/22 (32%)
leucine-rich repeat 146..169 CDD:275380 10/22 (45%)
LRR_8 169..226 CDD:290566 17/59 (29%)
leucine-rich repeat 170..193 CDD:275380 9/22 (41%)
LRR_RI 172..418 CDD:238064 66/258 (26%)
leucine-rich repeat 194..217 CDD:275380 5/25 (20%)
leucine-rich repeat 218..241 CDD:275380 7/22 (32%)
LRR_8 241..300 CDD:290566 13/58 (22%)
leucine-rich repeat 242..265 CDD:275380 5/22 (23%)
leucine-rich repeat 266..289 CDD:275380 3/22 (14%)
LRR_8 288..348 CDD:290566 18/69 (26%)
leucine-rich repeat 290..313 CDD:275380 6/22 (27%)
leucine-rich repeat 314..337 CDD:275380 8/22 (36%)
LRR_8 336..396 CDD:290566 17/69 (25%)
leucine-rich repeat 338..361 CDD:275380 8/32 (25%)
leucine-rich repeat 362..383 CDD:275380 2/20 (10%)
leucine-rich repeat 386..405 CDD:275380 8/18 (44%)
LRRCT 418..459 CDD:214507 3/5 (60%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
32.870

Return to query results.
Submit another query.