Protein Alignment cDIP and dma-1

DIOPT Version :9

• Sequence 1: NP_650951.1
• Gene: cDIP / 42512
• FlyBaseID: FBgn0038865
• Length: 554
• Species: Drosophila melanogaster
• Sequence 2: NP_492253.1
• Gene: dma-1 / 187968
• WormBaseID: WBGene00011345
• Length: 603
• Species: Caenorhabditis elegans
• Alignment Length: 414
• Identity: 103/414 - (24%)
• Similarity: 157/414 - (37%)
• Gaps: 93/414 - (22%)

  Fly    96 RTLIFENCTF--TNFPLRLFYTLEVSELDMRGCGIRFIYWENFSIGADKLVILLLSDNHIEVLPT 158
            |.|...||..  .:..:|| .:|||  ||:....|......||. |..||.:|.||.||:.:|||
 Worm    92 RVLRLINCQIPAMSRSIRL-PSLEV--LDLHSNNIEHATMSNFG-GMPKLRVLDLSSNHLNILPT 152

  Fly   159 KTFRGAGNLEFIFLNRNKLGKLQAGAFDNLLKLQYLDLTEN-----RLEALAADV---------F 209
            ..|.....|..:.|:.|.:..|.......|..|:.|.|..|     .:..|..||         .
 Worm   153 GVFTYLRALRSLSLSNNTISDLSTNLLRGLNSLRVLRLDRNPIPIEHINELFTDVSQLDELYLNH 217

  Fly   210 AGLKS-----------LRHVGLAGNQLTTIESDLFAHNPDLLSVAMQNNRLREVGEYAFRSRGRH 263
            ..|.|           ||.:|:.||.|..:.:......|.|..:.:.:|.::|:...||.:.
 Worm   218 CNLSSIYSLALDRIPQLRQLGIGGNNLKMVPTKELRSLPQLSVLDLSHNSIQEITACAFCNT--- 279

  Fly   264 HQMQYVDLSNNPELVVLLLNINATN-----------LTARNCSLDRVNLYGS---------VTNV 308
             .:..:|||:|      ||.|:..:           |...:.|.:.:|.:.|         :|::
 Worm   280 -NISKLDLSHN------LLGISKDSPFNEDAFRTMPLRHLDLSFNHMNDFDSKWLGWAQEELTSI 337

  Fly   309 DLSDNRVR---ELYFPASEALEHLVLRNNSL----VQLASLSRVPRLRHLDVADNPNLGQLPDGW 366
            .||.|.::   |.:....::|.||.|..|.:    |||.  ||...|..|:::.| .|..|||..
 Worm   338 ALSGNFLKNFEESWTYTLKSLIHLELAYNHIKFIPVQLP--SRYYHLISLNISGN-ELTYLPDNI 399

  Fly   367 RTPHLEMLVLRNTGQMELPLEALQGMQNLQKLDISGNNLTEIDPSAFPTLTQLTHFYIHGNNWNC 431
            .|              .||        |::..||:.|.......:....|..:...|:.||.|:|
 Worm   400 NT--------------LLP--------NVKTFDITANRFHTFSHTDLAFLNNVEQVYVDGNPWDC 442

  Fly   432 FSLRNIMDVLIRANGIAYTVDNYD 455
            ......:.|.:|.......:.|||
 Worm   443 SCAIQGLQVHMRDRYAMRHILNYD 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cDIP	NP_650951.1	leucine-rich repeat	118..142	CDD:275380	7/23 (30%)
		LRR_RI	143..407	CDD:238064	76/315 (24%)
		leucine-rich repeat	143..166	CDD:275380	10/22 (45%)
		LRR_8	166..225	CDD:290566	19/83 (23%)
		leucine-rich repeat	167..190	CDD:275380	5/22 (23%)
		leucine-rich repeat	191..214	CDD:275380	8/36 (22%)
		leucine-rich repeat	215..238	CDD:275380	6/22 (27%)
		leucine-rich repeat	239..265	CDD:275380	5/25 (20%)
		leucine-rich repeat	266..325	CDD:275380	16/81 (20%)
		LRR_8	304..357	CDD:290566	18/68 (26%)
		leucine-rich repeat	326..347	CDD:275380	10/24 (42%)
		leucine-rich repeat	348..394	CDD:275380	10/45 (22%)
		LRR_8	369..428	CDD:290566	9/58 (16%)
		LRR_4	393..433	CDD:289563	10/39 (26%)
		leucine-rich repeat	395..418	CDD:275380	4/22 (18%)
dma-1	NP_492253.1	LRR_8	90..147	CDD:338972	21/58 (36%)
		leucine-rich repeat	91..112	CDD:275380	6/20 (30%)
		leucine-rich repeat	113..136	CDD:275380	9/25 (36%)
		LRR	136..430	CDD:227223	78/328 (24%)
		leucine-rich repeat	137..160	CDD:275380	10/22 (45%)
		leucine-rich repeat	161..184	CDD:275380	5/22 (23%)
		leucine-rich repeat	185..209	CDD:275380	7/23 (30%)
		leucine-rich repeat	210..233	CDD:275380	2/22 (9%)
		leucine-rich repeat	234..257	CDD:275380	6/22 (27%)
		leucine-rich repeat	258..280	CDD:275380	5/25 (20%)
		leucine-rich repeat	281..307	CDD:275380	7/31 (23%)
		leucine-rich repeat	309..357	CDD:275380	9/47 (19%)
		leucine-rich repeat	382..405	CDD:275380	10/45 (22%)
		leucine-rich repeat	406..429	CDD:275380	4/22 (18%)
		TPKR_C2	438..>478	CDD:387596	8/29 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45617
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100