| Sequence 1: | NP_650948.2 | Gene: | Usp8 / 42509 | FlyBaseID: | FBgn0038862 | Length: | 896 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001122082.1 | Gene: | USP8 / 9101 | HGNCID: | 12631 | Length: | 1118 | Species: | Homo sapiens |
| Alignment Length: | 1128 | Identity: | 345/1128 - (30%) |
|---|---|---|---|
| Similarity: | 521/1128 - (46%) | Gaps: | 266/1128 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 5 KKLHMSSNLDDL-EKMSIIPDLRSKGMKILLNTARKLYMTAEEYRLDGDEELAYITYMKYFNMLT 68
Fly 69 AIHKKSDYPSHKTTVRQMLGDTESNRRIMDTLEEIINSLRHRYAQ-------------------Q 114
Fly 115 HQAPEPIAPDLVSNGRAGVDSPI-----TQPT--------QYARLGLITCQDLYRRMQEK--SVL 164
Fly 165 VMDCRPSADYEASHLTYYCAFNVPEELITPGMSAGRLQARLSSSAKASWASRSVKDSVVLMDW-- 227
Fly 228 NTKDAQPATNTAISTLLDILKNWDPDVTYRAPIQIVEGGYEYFIMMYPTHCTNPSVQAPQQNNND 292
Fly 293 IETID-DIEYPSIHD--------------ITMKEDI------------------------SAKDF 318
Fly 319 RP----------RPDFNRANKPAATRVNEQGISR----------------PSPPAKPI------- 350
Fly 351 ------AEIMRDQAEFLQ--------RAEQNDEQLEKASKMWKRQAAEGDGLNATEDQELHFRIL 401
Fly 402 QLESKAQDYI--VENNRLREE-----LSRIQELHNVTQQLSQKEVE---ATRNIESK-------- 448
Fly 449 IRERQRLDEQH------------------------------------ELERQERERLLAIARE-- 475
Fly 476 --------------------TKKHYKSPT----------------PSGPPSPGRNLEDVHVVSDS 504
Fly 505 LESLLQLT-GDPDPTIAPNKAE------IPTFDRAMKP--QPR-NVERTS-QRVRDFSPVIGQNV 558
Fly 559 GRGLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKT--NGQVIEEVAALIKEL 621
Fly 622 WNGQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQR--------- 677
Fly 678 EMISASEKAWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELPPNSNVCQLN 742
Fly 743 QCMDMYFSGERIHGWN---CPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKK-QN 803
Fly 804 YLRFPLENLDMNPYIARAESRAVTPKTYQLYAVSNHYGTMEGGHYTAFCKSANYGKWFKFDDQVV 868
Fly 869 SALDSSNVVSSAAYILFYTWLPP 891 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Usp8 | NP_650948.2 | USP8_dimer | 2..113 | CDD:286108 | 39/108 (36%) |
| RHOD | 148..278 | CDD:294087 | 47/133 (35%) | ||
| UCH | 562..886 | CDD:278850 | 156/338 (46%) | ||
| Peptidase_C19R | 564..887 | CDD:239139 | 155/337 (46%) | ||
| USP8 | NP_001122082.1 | USP8_dimer | 8..115 | CDD:312504 | 39/108 (36%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 120..177 | 5/56 (9%) | |||
| RHOD | 199..310 | CDD:197731 | 39/114 (34%) | ||
| tolA_full | 375..>547 | CDD:274303 | 33/177 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 402..447 | 8/44 (18%) | |||
| SH3-binding. /evidence=ECO:0000250 | 405..413 | 2/7 (29%) | |||
| MIP-T3 | 474..>646 | CDD:313469 | 33/178 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 475..648 | 33/179 (18%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 679..746 | 15/67 (22%) | |||
| UCH | 777..1106 | CDD:306860 | 155/337 (46%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165152606 | |
| Domainoid | 1 | 1.000 | 289 | 1.000 | Domainoid score | I1573 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG1868 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 1 | 1.000 | - | - | H3782 | |
| Inparanoid | 1 | 1.050 | 463 | 1.000 | Inparanoid score | I1559 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG47519 | |
| OrthoDB | 1 | 1.010 | - | - | D469048at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000821 | |
| OrthoInspector | 1 | 1.000 | - | - | oto90042 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101021 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR21646 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1591 |
| SonicParanoid | 1 | 1.000 | - | - | X4999 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 15 | 14.800 | |||||