DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp8 and LOC689730

DIOPT Version :9

Sequence 1:	NP_650948.2	Gene:	Usp8 / 42509	FlyBaseID:	FBgn0038862	Length:	896	Species:	Drosophila melanogaster
Sequence 2:	XP_038952348.1	Gene:	LOC689730 / 689730	RGDID:	1588758	Length:	541	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	109/394 - (27%)
Similarity:	180/394 - (45%)	Gaps:	82/394 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   516 DPTIAPNKAEIPTFDRAMKPQPRNVERTSQRVRDFSPVIG-QNVGRGLTGLKNLGNTCYMNSILQ 579
            ||.::|     |......:.:.|.:|..|.:.:   |.:. |.:....:||:|:||:||:|::||
  Rat    10 DPAMSP-----PATPELHQDEARVLEELSAKGK---PSLSLQRIQSPGSGLQNIGNSCYLNAVLQ 66

  Fly   580 CLSNTPQLTEYCISDKYKN---------------YISRS--NKTNGQVIEEVAALIKELWNGQYK 627
            ||::||.|.:|.:|.::..               ::::|  :..:|.|::....|
  Rat    67 CLTHTPPLADYMLSQEHSQRCCYPEGCKMCAMEAHVTQSLLHSHSGGVMKPSEIL---------- 121

  Fly   628 CVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQREMISASEKAWLEFTK 692
                          ...|....|:|:||||...::.:|.  ..|...:|.|            |.
  Rat   122 --------------TSTFHKHRQEDAHEFLMFTLNAMHE--SCLRGCKQSE------------TS 158

  Fly   693 AKESMILH-LFYGQMKSTVKCVACHKESATYESFSNLSLELPPNSNVCQLNQCMDMYFSGERIHG 756
            :|:|.::: :|.|||:|.:||..|.....:|:.|.||.|::....:|   .|.::.....|.:.|
  Rat   159 SKDSSLIYDIFGGQMRSQIKCHHCQGTLDSYDPFLNLFLDICSAQSV---KQALEDLVKLEELQG 220

  Fly   757 WN---CPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKKQNYLRFPLENLDMNPYI 818
            .|   |..|:.|..|.|...:.....||::.|.|.|....:     |....:.:| |.||:.||:
  Rat   221 DNAYYCGRCREKMPASKTTKVQTASKVLLLVLNRSYDFGGD-----KLNRVVSYP-EYLDLQPYL 279

  Fly   819 ARAESRAVTPKTYQLYAVSNHYG-TMEGGHYTAFCKSANYGKWFKFDDQVVSALDSSNVVSSAAY 882
            ::.   ...|..|.||||..|.| |...|||..:.| |::|||:|.||..|:..|.|:|:|..||
  Rat   280 SQP---TAGPLPYALYAVLVHDGVTCSSGHYFCYVK-ASHGKWYKMDDSKVTRCDVSSVLSEPAY 340

  Fly   883 ILFY 886
            :|||
  Rat   341 LLFY 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..113	CDD:286108
		RHOD	148..278	CDD:294087
		UCH	562..886	CDD:278850	98/345 (28%)
		Peptidase_C19R	564..887	CDD:239139	100/345 (29%)
LOC689730	XP_038952348.1	Peptidase_C19E	49..345	CDD:239126	100/347 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561804at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920