Protein Alignment Usp8 and Usp29

DIOPT Version :9

• Sequence 1: NP_650948.2
• Gene: Usp8 / 42509
• FlyBaseID: FBgn0038862
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: XP_011248964.1
• Gene: Usp29 / 57775
• MGIID: 1888998
• Length: 876
• Species: Mus musculus
• Alignment Length: 581
• Identity: 120/581 - (20%)
• Similarity: 204/581 - (35%)
• Gaps: 182/581 - (31%)

  Fly   276 THCTNPSVQAPQQNNNDIETID----DIEYPSIHDITMKEDISAKDFRPRPDFNRANKPAATRVN 336
            |.|.:.....|..:.:|:|:.|    :.:..:...:....:......|..| .:.:|.....:..
Mouse   113 TPCESQQPMEPMSSQDDLESSDPFCGEHQEAACGSLNTTPESGTPLSRKMP-LSMSNTTGGQKRG 176

  Fly   337 E-QGISRPSPPAKPIAEIMRDQAEFLQRAEQNDEQLEKASKMWKRQAAEGDGLNATEDQELHFRI 400
            | ||..|.:.|:...||:.:|..:     |...:|.:|:.:.:.|...
Mouse   177 EKQGRKRKTEPSSSSAEVNKDIPK-----ENTPDQKKKSRRYYSRNRG----------------- 219

  Fly   401 LQLESKAQDYIVENNRLREELSRIQELHNVTQQLSQKEVEATRNIESKIRERQRLDEQHELERQE 465
                .||:..:.    |||:..|           |..::|...|  ||...|..||
Mouse   220 ----GKAEKAVT----LREQEKR-----------SNWKLEPAFN--SKSYGRANLD--------- 254

  Fly   466 RERLLAIARETKKHYKSPTPSGPPSPGRNLEDVH------VVSDSLESLLQLTGDPDPTIAPNKA 524
             ..:|.||          |.|..       .||.      :..:.::||      |||.:...|.
Mouse   255 -GTILPIA----------TCSDD-------RDVSIFGLEIITHNGVQSL------PDPYLNQLKR 295

  Fly   525 EIPTFDRAMKPQPRNVERTSQRVRDFSPVIGQNVGRGLTGLKNLGNTCYMNSILQCLSNTPQLTE 589
            |                                      |..|||||||||||||.:...|...:
Mouse   296 E--------------------------------------GFPNLGNTCYMNSILQSVFGIPTFAK 322

  Fly   590 YCISDKYKNYISRSNKTNGQVIEEVA-----------ALIKELWNGQYKCVASRDLRYVVGQYQK 643
            ..:             |.|...|:|:           .::|::.:.:.|......::..:.....
Mouse   323 DLL-------------TQGIPWEKVSYDDLIMPLSQLLVLKDIRDVEIKGELLTSVKKSISTVAD 374

  Fly   644 IFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQREMI-----SASEKAWLEFTKAKESMILHLFY 703
            .|.|.:|.|:||||::.:|.|..:::.::.....|..     ||..|.::....|.....||
Mouse   375 TFSGNEQNDAHEFLSLCLDQLKLNMEKVNAMWDTERRNTCAGSAGTKRFVCPVGANFEFELH--- 436

  Fly   704 GQMKSTVKCVACHKESATYESFSNLSLEL--PPNSNVCQLNQCMDMYFSGERIHGWNCPSCKTKR 766
                |::.|..|.:.:...|..:.||::|  ...::...:.:..|::|:.|:|. .||..||.|
Mouse   437 ----SSIICEGCGEATIKTEVSNYLSIDLHHGTKTHPLSIQKSFDLFFTPEKIE-HNCEKCKNK- 495

  Fly   767 DAIKKLDISKLPPVLVVHLKRFYADPS----------------NSGSYMKKQNYLRFPLEN 811
            :::.|..:.:||.||:|||||:.....                |..|:..:...|.|||.|
Mouse   496 NSVLKYTLRRLPRVLIVHLKRYQVTTDLLPVKSEQPVEISKYLNISSHCHENRKLPFPLAN 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..113	CDD:286108
		RHOD	148..278	CDD:294087	1/1 (100%)
		UCH	562..886	CDD:278850	71/284 (25%)
		Peptidase_C19R	564..887	CDD:239139	71/282 (25%)
Usp29	XP_011248964.1	PH_USP37_like	11..116	CDD:270122	1/2 (50%)
		UBP14	<297..830	CDD:227532	71/282 (25%)
		UCH	297..>547	CDD:395355	66/271 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910