Protein Alignment Usp8 and Usp1

DIOPT Version :9

• Sequence 1: NP_650948.2
• Gene: Usp8 / 42509
• FlyBaseID: FBgn0038862
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: NP_001263061.1
• Gene: Usp1 / 43462
• FlyBaseID: FBgn0028476
• Length: 1078
• Species: Drosophila melanogaster
• Alignment Length: 967
• Identity: 185/967 - (19%)
• Similarity: 297/967 - (30%)
• Gaps: 386/967 - (39%)

  Fly    98 DTLEEIINSLRHRYAQQHQAPE-PIAPDLVSNGRAGVDSPITQPTQYARLGLITCQDLYRRMQEK 161
            :|.|  ||| :.|..||:|..| |:...  .|.....::||.|                   |||
  Fly    22 ETTE--INS-QLRQDQQNQEQENPLRQQ--DNSHPPQENPINQ-------------------QEK 62

  Fly   162 SVLVMDCRPSADYEASHLTYYCAFNVPEELI----TPGMSAGRLQARLSSSAKASWASRSVKDSV 222
            ..|        .....:....||.....:|:    ||.:|..:.:            .|.|..:.
  Fly    63 DTL--------QVSVLYPLVVCAQLADSQLVLTADTPKLSPVKKR------------QRRVYVAD 107

  Fly   223 VLMDWNTKDAQ-PATNTAISTLLDILKNWDPDVTYRAPIQIVEGGYEYFIMMYPTHCTNPSVQAP 286
            .|..::.:..| |||.             ||          :|||.:...::.|.    |.||||
  Fly   108 TLRCYSLRSRQEPATK-------------DP----------LEGGLKQPDVVPPP----PPVQAP 145

  Fly   287 QQNNNDIETIDDIEYPSIHDITMKEDISAKDF-------RPRPDFNRANKPAA---TRVNE--QG 339
            ...     ..:..||      |..|...::.:       .|:|...:...|..   ||.|:  :.
  Fly   146 SPT-----PTESTEY------TPPEQFKSEFWNRIEEAQEPKPVGKKRRTPGGLKRTRGNKLLKE 199

  Fly   340 ISRPSPPAKPIAEIMRDQAEF------------LQRAEQN-----DEQLEKASKMWKRQAAEGDG 387
            :...||  :..|.|...|||.            ..|...|     |.:.:..::  :|:.|.|.|
  Fly   200 LEIQSP--ETAAAIAAAQAELNAAGKSGAAGARSSRKRTNTMSLYDRRFQTTTE--ERRVANGYG 260

  Fly   388 LNAT-----------EDQE---------------------------------------------- 395
            .||.           |.||
  Fly   261 GNAARSVTGSSSNEIESQEPQSHQYYGPNGGSNAAGAGAGLNGSAAALNHAPSMGTLCNIGNSCY 325

  Fly   396 -----------LHFRILQLESKAQDY-IVENNRLREELSRIQEL-HNVT-QQLSQKEVEATRNI- 445
                       .|| :..|....||. :|:...:|::.:|...| .||: .||......:::::
  Fly   326 LNSVVYTLRFAPHF-LHNLHHLIQDLNVVQQTIVRQQTARSASLGKNVSAAQLEHARSWSSKDLA 389

  Fly   446 ---------------------ESKIRERQRLDEQHEL-------------ERQERERLLAIARET 476
                                 .||...:...::.|||             |....:.||...::.
  Fly   390 TSTDQYSGQNGGVNSGNGGSGSSKSTHQSVTEKLHELYNNLHGNEMADSTEPYHADTLLHAIQDV 454

  Fly   477 KKHYKSPTPSGPPSPGRNLEDVH--------VVSDSLESLLQLTGDPDPTIA----PNKAEIPT- 528
            ...::          |...:|.|        .:.::.:||::..|:....||    .|..|:.|
  Fly   455 NATFE----------GNQQQDAHEFLMCVLNCIRETNQSLIKAIGECPEVIANGYIANPDEVDTG 509

  Fly   529 ---------------------------------FDRAMK----PQPRNVERTSQRVRDFSPVIGQ 556
                                             |.|..|    .:|....|....:::.||..|.
  Fly   510 EGQDRTDSTASQNLNAGNGSLATSQTTTTKTSFFSRKSKRKDEVKPSKSTRVQSPLKENSPTAGG 574

  Fly   557 NVGRGLTGLKNLGNTCYMNSI-LQCLSNTPQLTEYCISDKYKNYISRSNKTNGQVIEEVAALIKE 620
            ..|.| |......:..|:|:: |...|:|..              |.|...:| |:...|||...
  Fly   575 ITGAG-TAHATANSLFYLNTVDLSGASSTSG--------------SASTSASG-VVSTSAALPTP 623

  Fly   621 LWNGQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQREMISASEK 685
            ....:|    |.|               |:.:|   .|:|.|.:..:      .|.||:.
  Fly   624 PQATKY----SSD---------------DEMNS---ATVLKDKMRLE------ERIRELN----- 655

  Fly   686 AWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELP------------PNSNV 738
              |.|..:.       |.|.:..|.||::|...:...:...::|:.:|            |::.:
  Fly   656 --LNFFSSD-------FEGIVVLTTKCLSCETITRQKQGMLDISVPVPISGYDNADLQDKPSTYI 711

  Fly   739 CQLNQCMDM-YFSGERIHGWNCPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKKQ 802
              .|.|:.. ||.||  :.::|..|....:||:.:....||.:||:.|.||      ||...|..
  Fly   712 --QNSCITKEYFRGE--NKYSCNQCTGYTEAIRSISYEVLPRLLVIQLNRF------SGGMEKVS 766

  Fly   803 NYL--RFPLENLDMNPYIAR-----AESRAVTPKTYQLYAVSNHYG-TMEGGHYTAF 851
            .|:  .|.|      |....     .|...:  ..|:||:|..|.| |:..|||.|:
  Fly   767 TYVPTTFTL------PCFCATCCELGEGNKL--HVYKLYSVITHVGATLTVGHYIAY 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..113	CDD:286108	6/14 (43%)
		RHOD	148..278	CDD:294087	23/134 (17%)
		UCH	562..886	CDD:278850	71/312 (23%)
		Peptidase_C19R	564..887	CDD:239139	70/310 (23%)
Usp1	NP_001263061.1	Peptidase_C19	308..819	CDD:271592	113/595 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456830
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930