Protein Alignment Usp8 and scny

DIOPT Version :9

• Sequence 1: NP_650948.2
• Gene: Usp8 / 42509
• FlyBaseID: FBgn0038862
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: NP_729092.1
• Gene: scny / 38648
• FlyBaseID: FBgn0260936
• Length: 1038
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 137/545 - (25%)
• Similarity: 219/545 - (40%)
• Gaps: 150/545 - (27%)

  Fly   412 VENNRLREELSRIQELHNVTQQLSQKE-----------VEATRNIESKIRERQRLDEQHELERQE 465
            |.|..|||.|.......:.|.|....|           ..|.|.:.:|| |.:.:...||
  Fly    13 VVNAALRESLGGNSSAGSSTDQAKSGEDTNGSLQNHIVANAKRILMAKI-EYEEVPNYHE----- 71

  Fly   466 RERLLAIARETKKHYKSPTPSGPPS----PGRNLEDVHVVSDSLESLLQLTGDPD---------- 516
                 ::....|..|....|..|.:    .|:|         :...|:...|..:
  Fly    72 -----SVLENLKSKYIVIKPGNPGAINGFSGKN---------NTGKLVGANGHDNNGARKQAEHP 122

  Fly   517 --------------PTIAPNKAEIPTFDRAMKPQPRNVE---RTSQRVRDFSPVIGQNVGRGLTG 564
                          ||..||  |:|...|.:.|: .|:.   :.|:|        ...||   ||
  Fly   123 NNQSHHINHHNHQHPTSNPN--ELPKPKRVLYPR-ENIRIGWKQSER--------KWQVG---TG 173

  Fly   565 LKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKTNGQVIEE-----VAALIKELWNG 624
            :.|:|||||:||.||.|.:.|.|..:.:|:       :::..:..|.|.     :.|:.|.|...
  Fly   174 MINVGNTCYLNSTLQALLHIPALANWLVSE-------QAHLADCNVAEPGSGCIICAMTKTLLAT 231

  Fly   625 QYKCVASRDL-----------RYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQRE 678
            |....|.|..           ..|||:         |:|:||||                   |.
  Fly   232 QSNQSAVRPFLIYSKLKQICKHMVVGR---------QEDAHEFL-------------------RF 268

  Fly   679 MISASEKAWL-EFTKAKE--------SMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELPP 734
            ::.|.|:|:| .|...||        :.:..:|.|.::|.|:|::|:..|.|::.|.:|.|::
  Fly   269 LVEAMERAYLMRFRNYKELDQLVKETTPLGQIFGGYLRSEVRCLSCNHVSITFQHFQDLLLDI-- 331

  Fly   735 NSNVCQLNQCMDMYFSGERIH--GWNCPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGS 797
             .....|....:.:||.||:.  |:.|..||.|..|.|:..:.:.|..|.:.||||    |..|:
  Fly   332 -RKADSLEDAFEGHFSRERLEDMGYKCEGCKKKVSATKQFSLERAPITLCIQLKRF----SMIGN 391

  Fly   798 YMKKQNYLRFPLENLDMNPYIARAESRAVTPKTYQLYAVSNHYGTMEG-GHYTAFCKSANYGKWF 861
            .:.||...:   ..:|::.|.||:::....|.||:|.::..|.|..:. |||||. .|.:.|.::
  Fly   392 KLTKQISFK---SRIDLSKYAARSQAAQAQPLTYRLVSMVTHLGASQHCGHYTAI-GSTDTGSFY 452

  Fly   862 KFDDQVVSALDSSNVVSSAAYILFY 886
            .|||..|..:...:|.::.|||:|:
  Fly   453 NFDDSYVRPIAMHSVCNTNAYIMFF 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..113	CDD:286108
		RHOD	148..278	CDD:294087
		UCH	562..886	CDD:278850	99/351 (28%)
		Peptidase_C19R	564..887	CDD:239139	99/351 (28%)
scny	NP_729092.1	Peptidase_C19E	171..477	CDD:239126	100/354 (28%)
		UCH	172..477	CDD:278850	99/350 (28%)
		Asp-B-Hydro_N	<617..>731	CDD:191249

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456846
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840