Protein Alignment Usp8 and Usp15-31

DIOPT Version :9

• Sequence 1: NP_650948.2
• Gene: Usp8 / 42509
• FlyBaseID: FBgn0038862
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: NP_611959.2
• Gene: Usp15-31 / 37954
• FlyBaseID: FBgn0050421
• Length: 1272
• Species: Drosophila melanogaster
• Alignment Length: 657
• Identity: 132/657 - (20%)
• Similarity: 195/657 - (29%)
• Gaps: 333/657 - (50%)

  Fly   561 GLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNK-------TNGQVIEEVAALI 618
            |:.||||.||||:||::|||||:|..|.||.:.|:||..:.|.||       |.|::.|::|.::
  Fly   263 GVMGLKNHGNTCFMNAVLQCLSHTDILAEYFVLDQYKADLKRRNKINSRKFGTKGELTEQLANVL 327

  Fly   619 KELWNGQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQR------ 677
            |.||..:.:...|...:.||.:|...||...|.|:.|||..|:|.:|.||.|....|.:
  Fly   328 KALWTCKNESDHSTSFKAVVDRYGTQFRSSTQHDAQEFLFWLLDKVHEDLNTASKRRYKSLKNSY 392

  Fly   678 ----EMISASEKAWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELP----- 733
                |:|:|...|  ...:...|.:..:|..|.:|::.|..|.|:|.|::.|..:|::||
  Fly   393 GRSDEVIAAETLA--NHIRCNNSFVQAVFQAQFRSSLTCPRCEKQSNTFDPFHCISVQLPQLTQQ 455

  Fly   734 ----------------------------------------------------------------- 733
                                                                             
  Fly   456 TIFVTVVYMTRLPRQVRMGLRVPAGSPIVALREQLQADTGIEGSRMVLVDLNAEGFTRVFYDTQP 520

  Fly   734 ----------------------------------------PNSNVCQ------------------ 740
                                                    |:....|
  Fly   521 VETLSSIETIYCIEVPAATPVAKAATPSETGDKSAPTAVTPSPAAAQSQADLLLLVANVYRAKDG 585

  Fly   741 ----------------------------------------------------------------- 740
                                                                             
  Fly   586 ADITRFGAPFSMKAPRDCSYQDLQKRMLREMAPLLKPEVFSYATPLAEMFRIRLQDPSADPDTYL 650

  Fly   741 ----------------------------------------------------------------- 740
                                                                             
  Fly   651 EQVEHPLLTEMIDMALSVLSSEAGPQHIKLLLEWSSPEAHFISKQQDTEEAVVEHESVARLSASK 715

  Fly   741 --------LNQCMDMYFSGERI---HGWNCPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSN 794
                    |.||::.|...|.:   ..|.||.|:.....:|.|.:..||.:||||.|||....|.
  Fly   716 PSDTAALTLEQCLEHYTKAETLSAEDAWRCPHCQQYLPVVKTLGLWSLPDILVVHFKRFRQHQSK 780

  Fly   795 SGSYMKKQNYLRFPLENLDMNPYIAR--------------------------------AESRAVT 827
            .....|....::|||...||:|::||                                .:||:.|
  Fly   781 GPQAAKLTTMVKFPLTAFDMSPHLARGVHESASSSLGMGTGIGLGLGLGSNPWKKARSVDSRSST 845

  Fly   828 PKT--------YQLYAVSNHYG-TMEGGHYTAFCKSANYGKWFKFDDQVVSALD----SSNVVSS 879
            ..:        |.||||..|.| |:|.|||||.||:....:|:|||||.||.:.    ..:::::
  Fly   846 LNSRCDAKDTRYDLYAVCYHQGDTLETGHYTAACKNPYDRQWYKFDDQRVSKVPEDDIEQDIINN 910

  Fly   880 AAYILFY 886
            .||:|||
  Fly   911 EAYMLFY 917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..113	CDD:286108
		RHOD	148..278	CDD:294087
		UCH	562..886	CDD:278850	129/654 (20%)
		Peptidase_C19R	564..887	CDD:239139	131/654 (20%)
Usp15-31	NP_611959.2	Peptidase_C19	<262..>383	CDD:271592	50/119 (42%)
		Peptidase_C19	266..>461	CDD:271592	67/196 (34%)
		Peptidase_C19R	<713..918	CDD:239139	62/205 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456847
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21646
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030