Protein Alignment Usp8 and DUBAI

DIOPT Version :9

• Sequence 1: NP_650948.2
• Gene: Usp8 / 42509
• FlyBaseID: FBgn0038862
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: NP_610784.1
• Gene: DUBAI / 36361
• FlyBaseID: FBgn0033738
• Length: 852
• Species: Drosophila melanogaster
• Alignment Length: 656
• Identity: 153/656 - (23%)
• Similarity: 247/656 - (37%)
• Gaps: 183/656 - (27%)

  Fly   345 PPAKPIAEIMR--DQAEFLQRA----EQN--DEQLEKASKM---WKRQAAEGDGLN--------A 390
            ||:..:|.:.:  |..:.|:..    |||  |..::|...:   |.........||        .
  Fly   152 PPSCAVAIVFQLFDSTQILEAVHSLLEQNVQDSSIKKTVNLLCDWITYCTFCSTLNLWVLALLKG 216

  Fly   391 TEDQELHFRILQLESKAQDYIVENNRLREELSRIQELHNVTQQLSQKEVEATRNIESKIRER--- 452
            ..||.   ::..|:..|.|.|       |:|..:.    :...|.||......::.|.|.:.
  Fly   217 LRDQG---KMALLDEIAMDNI-------EKLFHVM----IFPALRQKAAPVVFHMLSTINQTPEV 267

  Fly   453 -----QRLDEQHELERQERERLLAIARETKKHYKSPTPSGPPSPGRNLEDVHVVSDSLESLLQLT 512
                 .|:....:..:.:...:..|..||||                         .|:.|:.||
  Fly   268 FHKILPRIPRVLQYVKNQSTTMDEIGLETKK-------------------------CLQQLVDLT 307

  Fly   513 G-------DPDPTIAPNKAEIPTFDRAMKPQPRNVERTSQRVRDFSPVIGQNVGRGLTGLKNLGN 570
            .       |.|......|..:.|::    |.| |....::.:.:.:...|:...|  .||.||||
  Fly   308 SALMLRFYDQDELYVATKKALQTYE----PSP-NCVALAKAMHENAQPWGRRNAR--VGLVNLGN 365

  Fly   571 TCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKTNGQVIEEVAALIKELWNGQYKCVASRDLR 635
            ||||||:||.|:.|...:...:      .|..::....:|.:::|.:...|   :|:...||.|.
  Fly   366 TCYMNSVLQALAMTSDFSRQIL------LIECNSVLLMKVQQQIALMHHSL---RYELTPSRVLN 421

  Fly   636 ------YVVGQYQKIFRGVDQQDSHEFLTILMDWLH-----SDLQTLH-------------VP-- 674
                  :..|.         ||||.|||..|:|.||     |...|.|             ||
  Fly   422 ATRPPSFTPGL---------QQDSSEFLGYLLDLLHEHEINSSSVTGHSVGPPKTGREVDDVPAL 477

  Fly   675 ---------------RQREMISAS------------------------EKAWLEFTKAK-ESMIL 699
                           :..|:.|.|                        ::...:..:|| .|.|.
  Fly   478 LSEDILSSGVIPYNSKDHELSSGSNSDNCNHKPTPTPPATPTKATNGLKQQGQQVDQAKPPSTID 542

  Fly   700 HLFYGQMKSTVKCVACHKESATYESFSNLSLELPPNSNVC-----QLNQCMDMYFSGERIHGWN- 758
            ..|.|::.:|.:|:.|..||...:||..|.|..|.:...|     .:...::.|.|.|::.|.|
  Fly   543 KTFAGKLSTTYRCLNCGWESRNEDSFRELQLSFPDDKEDCGATNYSVQDLIEYYCSPEKLDGDNQ 607

  Fly   759 --CPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKKQNYLRFPLENLDMNPYIARA 821
              ||.||...||.:.:.:::.|..|::.||:|..|  ....:..|..:..|..|::.:. ..|:.
  Fly   608 YFCPQCKKLCDAERHIGVTQAPKNLILTLKQFKYD--QKYHFRTKLMHKVFHDESVTVK-MSAKD 669

  Fly   822 ESRAVTPKTYQLYAVSNHYG-TMEGGHYTAFCKSANYGK-WFKFDDQVVS---ALDSSNVVS-SA 880
            ..:.::...|.|||...|.| :|:.|||..|  :|:..| |:||:|.||:   ..:..|:.| :.
  Fly   670 SLQEMSTVHYDLYAGVVHAGYSMDSGHYFTF--AADQAKNWYKFNDNVVTHSKPEEMHNLTSPNT 732

  Fly   881 AYILFY 886
            .|||||
  Fly   733 PYILFY 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..113	CDD:286108
		RHOD	148..278	CDD:294087
		UCH	562..886	CDD:278850	106/403 (26%)
		Peptidase_C19R	564..887	CDD:239139	108/403 (27%)
DUBAI	NP_610784.1	UCH	358..738	CDD:278850	106/402 (26%)
		Peptidase_C19H	359..739	CDD:239129	108/403 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456845
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840