Protein Alignment Usp8 and Usp16-45

DIOPT Version :9

• Sequence 1: NP_650948.2
• Gene: Usp8 / 42509
• FlyBaseID: FBgn0038862
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: NP_001284890.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Alignment Length: 962
• Identity: 176/962 - (18%)
• Similarity: 296/962 - (30%)
• Gaps: 354/962 - (36%)

  Fly    33 LLNTARKLYMTAEEYRL---------DGDEELAYI--TYMKYFNMLTAIHKKSDYPSHKTTVRQM 86
            ||:..::|....||:.|         .||.||..|  |...:..:..|:       ::.....|.
  Fly   330 LLSVLKELSEPGEEFILPGGTFTIKDKGDIELPMIKGTLSSWGGLTAAL-------ANALEELQA 387

  Fly    87 LGDTESNRRIMD-------------------TLEEIINSLRH----RYAQ--------QHQAPEP 120
            .|...:.|::.|                   .|.:::.|:|:    ||.:        :.|....
  Fly   388 GGSVFTPRKLFDRLCVKCPQFTGGDQHDAHELLRQLLESVRNEDLKRYQRVILQNLGYKDQDVNS 452

  Fly   121 IAPDL-----VSNGRAGVDSPITQPTQYAR---LGLITCQDLYRRMQEKSVLVMDCRPSADYEAS 177
            ::.::     :...:||  ..|.:|.|..|   :..:||||.:.                  .:|
  Fly   453 VSEEMRQKCKIYGNQAG--DRILRPEQVFRGFLVSTLTCQDCHN------------------VSS 497

  Fly   178 HLTYYCAFNVPEELITPGMSAGRLQARLSSSAKASWASRSVKDSVVLMDWNTKDAQPATNTAIST 242
            ...|:...::|..:..|.....|   :.|.....:.:|.||..|.         .||..||
  Fly   498 RHEYFLDMSLPVAVEKPQPPQRR---KPSPELSLTSSSSSVTPST---------GQPTINT---- 546

  Fly   243 LLDILKNWDPDVTYRAPIQIVEGGYEYFIMMYPTHCTNPSVQAPQQNNNDIETIDDIEYPSIHDI 307
                 |..|..|.:.|      ....:|:..:......||
  Fly   547 -----KFTDGSVNFTA------SSPSFFLHAHEAASLGPS------------------------- 575

  Fly   308 TMKEDISAKDFRPRPDFNRANKPAATRVNEQGISRPSPPAKPIAEIMRDQAEFLQRAEQNDEQLE 372
              |..:..:..|.|.....|.|...:.:|..|               .|.....:.||..|:...
  Fly   576 --KSQVKKEKERQRKAKRAAKKRQKSSLNLNG---------------NDSGNGNELAESVDQDDA 623

  Fly   373 KASKMWKRQAAEGDGLNATEDQ-ELHFRILQLESKAQDYIVENNRLREELSRIQELHNVTQQLSQ 436
            ..:.:........|||..|..| |.........|:..|..||:|.:.:..:
  Fly   624 SLASLGAGDGQANDGLEQTNGQTEDSTTSSVTTSEHSDADVEDNLVEDTAA-------------- 674

  Fly   437 KEVEATRNIESKIRERQRLDEQHELERQERERLLAIARETKKHYKSPTPSGPPSPGRNLEDVHVV 501
               .:|.|:.|.                    ..::...:|.:..|...:.||...|:....|:.
  Fly   675 ---PSTNNVPSS--------------------TASLTAPSKTYMDSNGNAQPPGEKRDDTPEHMD 716

  Fly   502 SDSLESLLQLTGDPDPTIAPNKAEIPTFDRAMKPQPRNVERTSQRVRDFSPVIGQNVGRGLTGLK 566
            .||||.     .:.|..||.:.|          |...|...::....:.:.|    .|.||:|
  Fly   717 KDSLEE-----DENDSGIATSPA----------PTATNSSTSTSATGNNNSV----AGSGLSG-- 760

  Fly   567 NLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKTNGQVIEEVAALIKELWNGQYKCVAS 631
                                     .|...::.::.::.....:.|:.|::|:::
  Fly   761 -------------------------SSGALEDPLAPASLVTAGLSEKGASVIRQV---------- 790

  Fly   632 RDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQREMISASEKAWLEFTKAKES 696
                 .||..|....|.:..|.                      :.:.|...||.
  Fly   791 -----SVGAEQGASNGTEDADG----------------------EAKAIEQPEKT---------- 818

  Fly   697 MILHLFYGQMKSTVKCVACHKESATYESFSNLSLELPP----NSNVCQLNQCMDMYFSGERIHGW 757
                  ..|.::..:..|..|...| :|:|:.|..:.|    ....|.:..|::.:.:.|.:.|.
  Fly   819 ------PSQAQAMAQAQARTKRVRT-QSYSDWSTTIAPRYQCEDGECSVQSCLNNFTAVELMTGQ 876

  Fly   758 N---CPSCKTKR-------------DAIKKLDISKLPPVLVVHLKRFYADP-------SNSGSYM 799
            |   |.|| |:|             :|.|:|.:|..|.||::|||||...|       :...||.
  Fly   877 NKVGCDSC-TQRINGSDPKAKSVNTNATKQLLVSSPPAVLILHLKRFQLGPRCIFRKLTRPVSYP 940

  Fly   800 KKQNYLRF---PLENLDMNPYIARAESRAVTPKTYQLYAVSNHYGTMEGGHYTAFC----KSANY 857
            ...:...|   .::||   |.|.|.:.:.:    |.||.|..|.|.|.||||||:.    |.|..
  Fly   941 NLLDIAAFCGSKVKNL---PNIDRKQKKLL----YALYGVVEHSGGMYGGHYTAYVKVRPKVAPG 998

  Fly   858 GKWFKF------------DDQV----------------VSALDSSNVVSSAA 881
            .|.:||            |||:                :..||.|:..|:::
  Fly   999 DKRWKFLPHGSKAELDQDDDQLKKLEELLAKEKAREQHLKVLDDSDDFSNSS 1050

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..113	CDD:286108	22/113 (19%)
		RHOD	148..278	CDD:294087	23/129 (18%)
		UCH	562..886	CDD:278850	78/382 (20%)
		Peptidase_C19R	564..887	CDD:239139	77/380 (20%)
Usp16-45	NP_001284890.1	zf-UBP	108..159	CDD:280334
		Peptidase_C19	307..>512	CDD:271592	36/208 (17%)
		Peptidase_C19K	<849..1123	CDD:239132	57/210 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456856
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930