Protein Alignment Usp8 and ubp1

DIOPT Version :10

• Sequence 1: NP_650948.2
• Gene: Usp8 / 42509
• FlyBaseID: FBgn0038862
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: NP_587999.1
• Gene: ubp1 / 2539228
• PomBaseID: SPCC16A11.12C
• Length: 849
• Species: Schizosaccharomyces pombe
• Alignment Length: 575
• Identity: 128/575 - (22%)
• Similarity: 201/575 - (34%)
• Gaps: 255/575 - (44%)

  Fly   561 GLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKTN--GQVIEEVAALIKELWN 623
            ||.||.||||:|||||.|||:.:|.:||:|.:||.|:..|:.:|...  |:|....|:|:|.:.:
pombe   277 GLCGLYNLGNSCYMNSALQCMIHTHELTKYFLSDSYEKDINYNNPLGMMGKVALSYASLLKMIHH 341

  Fly   624 -GQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDL-----------------QT 670
             .....|:....::::|::...|.|..||||.||:...:|.||.||                 ..
pombe   342 TADMHSVSPSSFKFIIGEFNTYFSGYRQQDSQEFIAFFLDGLHEDLNRIQIKPYFERPDLFDEHP 406

  Fly   671 LHVPRQREMISASEKAWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELPPN 735
            |||.|      .:.:.|...||..:|:|:.||.|..|||::|..|:::|..::.|..|:|.||.:
pombe   407 LHVQR------VANQCWDIHTKRNDSIIVQLFQGMYKSTLECSICYQKSTAFDPFMYLTLPLPTS 465

  Fly   736 ----------------------------SNVCQLN------------QC-----MDMYFS----- 750
                                        |.|.|:.            :|     .|:|..
pombe   466 AKWRHKVVYVPPFGTQSPVELYLELLMESTVIQMKFQATEKLQKMGLECGELTACDIYRGKVYKV 530

  Fly   751 -------GERIHGWN-------------------------------------------------- 758
                   .::||.|:
pombe   531 LKNKDKISKKIHKWDHVVLYGSTANGLTIPIVHGCKRPAMPGSYQSNDVFGFPLQLNVRSRNVLT 595

  Fly   759 ----------------------------------------------------------------- 758
                                                                             
pombe   596 NDLVKEIVELYRVYAGIDVAIGTLQLGLKRMESKAGKWECIKEIEVKRFEIVEEEEIVIDDKTVI 660

  Fly   759 ----------------------------------------------------CPSCKTKRDAIKK 771
                                                                ||.||..|.|.|:
pombe   661 MCLWNDQQYEKLFYNCEWIFEKIQFHMESITLEDCLLEFSKPEQLDLQDSWYCPGCKAFRPATKR 725

  Fly   772 LDISKLPPVLVVHLKRFYADPSNSGSYMKKQNYLRFPLENLD----MNPYIARAE-SRAVTPKTY 831
            |:|.:||.:||:||.||.....:.....|:::.:.:|:.:|:    ::|:|...| ..:.....|
pombe   726 LEIWRLPKILVIHLNRFSGHGGDLRRRRKRRDLVVYPVFDLNLKQFLSPFIKDHEWLSSQKSMLY 790

  Fly   832 QLYAVSNHYGTMEGGHYTAFCKSANYGKWFKFDDQVVSALDSSNVVSSAAYILFY 886
            .||||.||:|.|..|||||:.:.|:...:|||||..:..:|..::|:|:||:|||
pombe   791 DLYAVDNHHGFMSNGHYTAYARDASSQTFFKFDDTAICEIDPEDIVTSSAYVLFY 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..114	CDD:462647
		RHOD	148..278	CDD:444705
		Smc	<361..>511	CDD:440809
		Peptidase_C19R	564..887	CDD:239139	126/572 (22%)
ubp1	NP_587999.1	UBP12	1..849	CDD:227847	128/575 (22%)