Protein Alignment Usp8 and Usp4

DIOPT Version :9

• Sequence 1: NP_650948.2
• Gene: Usp8 / 42509
• FlyBaseID: FBgn0038862
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: XP_006511759.1
• Gene: Usp4 / 22258
• MGIID: 98905
• Length: 967
• Species: Mus musculus
• Alignment Length: 636
• Identity: 145/636 - (22%)
• Similarity: 197/636 - (30%)
• Gaps: 321/636 - (50%)

  Fly   561 GLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNK--TNGQVIEEVAALIKELWN 623
            ||.||.||||||:|||.|||||||..||||.:.|:|:..|:|.|.  ..|::.|..|.|||::|:
Mouse   300 GLCGLGNLGNTCFMNSALQCLSNTAPLTEYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMWS 364

  Fly   624 GQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQREMISA------ 682
            |:...||.|..:..||::...|.|..||||.|.|..::|.||.||..:......|...|
Mouse   365 GRDTHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFILDGLHEDLNRVKKKPYLEPKDANGRPDA 429

  Fly   683 --SEKAWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELP------------ 733
              :::||.......:|:|:..|:|..|||:.|..|.|.|.|::.|..|:|.||
Mouse   430 VVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRIMEVFLV 494

  Fly   734 ---PN----------------SNVCQ--------------------------------------- 740
               |.                |::|:
Mouse   495 PADPQCRPIQYRVTVPLMGAISDLCEALSKLSGIAAENMVVTDVYNHRFHKIFQMDEGLSHITPR 559

  Fly   741 --------LNQCMD--------MYF---------------------------------------- 749
                    .|..||        :||
Mouse   560 DDIFVYEVCNTSMDGSECITLPVYFREKKSRPSSASSGAVLYGQPLLVSVPKHKLTLESLYQAVC 624

  Fly   750 ----------------------------------------------------------------- 749
                                                                             
Mouse   625 DRISRYIKQPLPDEFLSSPLEPGACNGSRSSYEGDEEEEMDHQEEGKEQLSEVEGSGEDDQGDDH 689

  Fly   750 --SGERIHG-------------------------------------------------------- 756
              |.:::.|
Mouse   690 SESAQKVKGQPRHKRLFTFSLVNSCGTADINSLATDGKLLKLNSRSTLAIDWDSETRSLYFDEQE 754

  Fly   757 ----------------------------------------------WNCPSCKTKRDAIKKLDIS 775
                                                          |.||:||..:.|.||.|:.
Mouse   755 SECFSPQACEKHLSMSQPQKKKKAAVALRECIELFTTMETLGEHDPWYCPTCKKHQQATKKFDLW 819

  Fly   776 KLPPVLVVHLKRFYADPSNSGSYM-----KKQNYLRFPLENLDMNPYIARAESRAVTPKTYQLYA 835
            .||.:||||||||        ||.     |....:.||:..|:|:.::.   .|:..|..|.|.|
Mouse   820 SLPKILVVHLKRF--------SYNRYWRDKLDTVVEFPVRALNMSEFVC---DRSARPYVYDLIA 873

  Fly   836 VSNHYGTMEGGHYTAFCKSANYGKWFKFDDQVVSALDSSNVVSSAAYILFY 886
            ||||||.|..|||||:.|:...|||:.|||..||......:|:.|||:|||
Mouse   874 VSNHYGAMGVGHYTAYAKNRLNGKWYYFDDSSVSLASEDQIVTKAAYVLFY 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..113	CDD:286108
		RHOD	148..278	CDD:294087
		UCH	562..886	CDD:278850	142/633 (22%)
		Peptidase_C19R	564..887	CDD:239139	143/633 (23%)
Usp4	XP_006511759.1	UBP12	35..927	CDD:227847	145/636 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1591
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940