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Protein Alignment Usp8 and Usp22

DIOPT Version :9

Sequence 1:	NP_650948.2	Gene:	Usp8 / 42509	FlyBaseID:	FBgn0038862	Length:	896	Species:	Drosophila melanogaster
Sequence 2:	NP_001004143.2	Gene:	Usp22 / 216825	MGIID:	2144157	Length:	525	Species:	Mus musculus

Alignment Length:	432	Identity:	124/432 - (28%)
Similarity:	200/432 - (46%)	Gaps:	77/432 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   496 EDVHVVSDSLES---LLQLTGDPDPTIAPNKAEIPTFDRAMKPQPRNVERTSQRVRDFSPVIGQN 557
            :|:.:::...:.   .:|..|:...|..|.|.|:    ..:|..|:..:.||            |
Mouse   122 KDIEIIAKEEQRKAWKMQGVGEKFSTWEPTKREL----ELLKHNPKRRKITS------------N 170

  Fly   558 VGRGLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKTNGQVIEEVAALIKELW 622
            ...||.||.||||||:||.|:|.|::||.|.::.:||:::   ......:..::.|:::|.:|.:
Mouse   171 CTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHR---CEMQSPSSCLVCEMSSLFQEFY 232

  Fly   623 NGQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQREMISASEKAW 687
            :|.........|.::|..:.:...|.:|||:||||...:|.||         |..:.....:||
Mouse   233 SGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLH---------RHCKGDDNGKKA- 287

  Fly   688 LEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELPPN----------------- 735
             ........:|..:|.|.::|.|.|..||..|.|.:.|.::||:||.:
Mouse   288 -NNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGSVVN 351

  Fly   736 -----SNVCQLNQCMDMYFSGERIHG---WNCPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADP 792
                 |....|..|:..:...|.:..   ..|..|.:.:::.|:|.:.|||.|...|||||
Mouse   352 GESHASGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRF---- 412

  Fly   793 SNSGSYMKK-QNYLRFPLENLDMNPYIARA-ESR-----------AVTPKTYQLYAVSNHYGTME 844
            .:|....:| ..|:.|||| |||.|::|.: |||           ......|.|:||.||.||:|
Mouse   413 EHSAKLRRKITTYVSFPLE-LDMTPFMASSKESRMNGQYQQPLDSLNNDNKYSLFAVVNHQGTLE 476

  Fly   845 GGHYTAFCKSANYGKWFKFDDQVVSALDSSNVVSSAAYILFY 886
            .||||:|.:. :..:|||.||.:::.....:|:.|..|:|||
Mouse   477 SGHYTSFIRQ-HKDQWFKCDDAIITKASIKDVLDSEGYLLFY 517

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.