Protein Alignment Usp8 and math-33

DIOPT Version :10

• Sequence 1: NP_650948.2
• Gene: Usp8 / 42509
• FlyBaseID: FBgn0038862
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: NP_001294689.1
• Gene: math-33 / 179538
• WormBaseID: WBGene00010406
• Length: 1138
• Species: Caenorhabditis elegans
• Alignment Length: 450
• Identity: 112/450 - (24%)
• Similarity: 177/450 - (39%)
• Gaps: 133/450 - (29%)

  Fly   494 NLEDVHVVSDSLESLLQLTGDPDPTIAPNKAEIPTFDRAMKPQPRNVERTSQRVRDFSPVIGQNV 558
            |.:|.:||:|:::...:.|           |::||....|....|:.
 Worm   158 NPKDGYVVNDTIKLRCRFT-----------ADVPTGANYMWDSKRHT------------------ 193

  Fly   559 GRGLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYI------SRSNKTNGQVIEEVAAL 617
              |..||:|.|.|||||||||         .:..:..::..:      :..|::|  ::..:..:
 Worm   194 --GCIGLRNQGATCYMNSILQ---------SFYFTTGFRRAVYNMDVGTEPNESN--IVLAMQRV 245

  Fly   618 IKELWNGQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLHSDLQTLHVPRQREMISA 682
            ..||.... :.|.:..|....| :.|: ...:|.|..||..:|:|    :|:|       :|...
 Worm   246 FYELQMAS-EAVETNSLTRAFG-WDKL-DAFNQHDVQEFCRVLLD----NLET-------KMKGT 296

  Fly   683 SEKAWLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELPPNSNVCQLNQCMDM 747
            ||          |..|.:||.|.|||.:||:....||:..|||.::.|.:   ..:..|.:..:.
 Worm   297 SE----------EKSIPNLFRGNMKSYIKCLDVDYESSRTESFYDVQLNV---LGMDSLERAFEA 348

  Fly   748 YFSGERIHGWNCPSCKTKRD--------AIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKKQNY 804
            |.:.|.:...|      |.|        |.|.:...:|||:|.|.|.||    ...|...|....
 Worm   349 YTTSEILDDEN------KYDAGDHGLQRAEKGVKFVELPPILHVQLMRF----QYCGVEQKINER 403

  Fly   805 LRFPLE-NL----DMNPYIARAESRAVTPKTYQLYAVSNHYGTMEGGHYTAFC-----KSA---- 855
            ..||.: ||    ::.|.:...:.      .|.|:||..|.|...||||..:.     :||
 Worm   404 FSFPEKMNLASCCELGPMLTEEDC------VYSLHAVLVHSGEFHGGHYVTYINVNLHESAVDPT 462

  Fly   856 NYGKWFKFDDQVVSALDSSNVV----------SSAAYILFYTW----------LPPMQVP 895
            :..||.||||.|||...:.:.:          :|:||:|.|..          :|..|:|
 Worm   463 SSAKWCKFDDDVVSRTTTDDAIVSNFGGEKTMNSSAYMLVYVRDNAIDQFLAPIPDSQIP 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..114	CDD:462647
		RHOD	148..278	CDD:444705
		Smc	<361..>511	CDD:440809	5/16 (31%)
		Peptidase_C19R	564..887	CDD:239139	96/360 (27%)
math-33	NP_001294689.1	MATH	30..182	CDD:445786	8/34 (24%)
		peptidase_C19C	194..507	CDD:239124	98/366 (27%)
		USP7_ICP0_bdg	682..863	CDD:463580
		USP7_C2	900..1125	CDD:464201