Protein Alignment Usp8 and Usp17lc

DIOPT Version :9

• Sequence 1: NP_650948.2
• Gene: Usp8 / 42509
• FlyBaseID: FBgn0038862
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: NP_034219.3
• Gene: Usp17lc / 13532
• MGIID: 107698
• Length: 545
• Species: Mus musculus
• Alignment Length: 427
• Identity: 119/427 - (27%)
• Similarity: 187/427 - (43%)
• Gaps: 114/427 - (26%)

  Fly   485 PSGPP---SPGRNLEDVHVVSDSLESLLQLTGDPDPTIAPNKAEIPTFDRAMKPQPRNVERTSQR 546
            |...|   |||  .:.:|  .|..:.:::||.:..|:::   .|.|.
Mouse     8 PEADPALSSPG--AQQLH--QDEAQVVVELTANDKPSLS---WECPQ------------------ 47

  Fly   547 VRDFSPVIGQNVGRGLTGLKNLGNTCYMNSILQCLSNTPQLTEYCISDKYKN------------- 598
                        |.| .||:|.||:||:|:.||||::||.|.:|.:|.:|..
Mouse    48 ------------GPG-CGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEYSQTCCSPEGCKMCAM 99

  Fly   599 --YISRS--NKTNGQVIEEVAALIKELWNGQYKCVASRDLRYVVGQYQKIFRGVDQQDSHEFLTI 659
              ::::|  :..:|.|::....|                        ...|....|:|:||||..
Mouse   100 EAHVTQSLLHSHSGDVMKPSQIL------------------------TSAFHKHQQEDAHEFLMF 140

  Fly   660 LMDWLHSDLQTLHVPRQREMISASEKAWLEFTKAKESMILH-LFYGQMKSTVKCVACHKESATYE 723
            .::.:|.  ..|.|.||.|..|            ::|..:| :|.|..:|.:||:.|...|.||:
Mouse   141 TLETMHE--SCLQVHRQSEPTS------------EDSSPIHDIFGGLWRSQIKCLHCQGTSDTYD 191

  Fly   724 SFSNLSLELPPNSNVCQLNQCMDMYFSGERIHGWN---CPSCKTKRDAIKKLDISKLPPVLVVHL 785
            .|.::.|::   |:...:||.:......|.:.|.|   |..|:.|..|.|.|.|...|.||::.|
Mouse   192 RFLDVPLDI---SSAQSVNQALWDTEKSEELRGENAYYCGRCRQKMPASKTLHIHSAPKVLLLVL 253

  Fly   786 KRFYADPSNSGSYMKKQNYLRFPLENLDMNPYIARAESRAVTPKTYQLYAVSNHYG-TMEGGHYT 849
            |||.|...|     |....:.:| |.||:.||:::...   .|..|.||||..|.| |...|||.
Mouse   254 KRFSAFMGN-----KLDRKVSYP-EFLDLKPYLSQPTG---GPLPYALYAVLVHEGATCHSGHYF 309

  Fly   850 AFCKSANYGKWFKFDDQVVSALDSSNVVSSAAYILFY 886
            ::.| |.:|.|:|.||..|::.|.::|::..||:|||
Mouse   310 SYVK-ARHGAWYKMDDTKVTSCDVTSVLNENAYVLFY 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..113	CDD:286108
		RHOD	148..278	CDD:294087
		UCH	562..886	CDD:278850	103/345 (30%)
		Peptidase_C19R	564..887	CDD:239139	105/345 (30%)
Usp17lc	NP_034219.3	Peptidase_C19E	50..346	CDD:239126	106/348 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	368..442
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	489..539

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561804at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920