Protein Alignment Usp8 and usp21

DIOPT Version :9

• Sequence 1: NP_650948.2
• Gene: Usp8 / 42509
• FlyBaseID: FBgn0038862
• Length: 896
• Species: Drosophila melanogaster
• Sequence 2: XP_031746854.1
• Gene: usp21 / 100487480
• XenbaseID: XB-GENE-970097
• Length: 618
• Species: Xenopus tropicalis
• Alignment Length: 615
• Identity: 164/615 - (26%)
• Similarity: 255/615 - (41%)
• Gaps: 152/615 - (24%)

  Fly   314 SAKDFRPRPDFNRANKPAATRVNEQGIS----RPSPPAKPIAEI-MRDQAEFLQRAEQNDEQLEK 373
            |||...|.|.....:...:..|:...:|    :|...||.:|.: :|:::....|....|..|.|
 Frog   118 SAKGTAPPPGGRAGSLSRSKSVSHGDLSATREKPEEVAKSLARVSLRERSASSTRKPLLDTSLLK 182

  Fly   374 ASKMWKRQAAEGDGLNATEDQELHFRILQLESKAQDYIVENNRLREELSRIQELHNVTQQLSQKE 438
            .|...||                                              ||.:....||::
 Frog   183 RSSSLKR----------------------------------------------LHVLPVLESQQK 201

  Fly   439 VEATRNIESKIRERQRLDEQHELERQERERLLAIARETKKHYKSPTPSGPPSPGRNLEDVHVVSD 503
            ::::|:.:.....:....||||.:.:.:   |..|..|.      ...||...|
 Frog   202 LDSSRSSQLGASTKASASEQHEGDGRYQ---LGRASHTS------ASDGPVCNG----------- 246

  Fly   504 SLESLLQLTGDPDPTIAPNKAEIPTFDRAM---KPQPRNVERTSQRVRDFSPVIGQNVGRGLTGL 565
                                  |...|||:   .|.||            .|.:|.    |..||
 Frog   247 ----------------------IKAQDRALSVTSPPPR------------LPALGS----GHVGL 273

  Fly   566 KNLGNTCYMNSILQCLSNTPQLTEYCISDKYKNYISRSNKTNGQVIEEVAALIKELWNGQYKCVA 630
            :||||||:||::|||||:|..|.:|.:..:|:.....|.|...::.|..|.:|..||:......|
 Frog   274 RNLGNTCFMNAVLQCLSSTKPLRDYILRQEYRQEQPGSCKAQQELTEAFADVIASLWSPDPPDAA 338

  Fly   631 S-RDLRYVVGQYQKIFRGVDQQDSHEFLTILMDWLH--------------SDLQTLHVPRQREMI 680
            : ..|:.|..:|...|.|..|||:.|||...||.:|              ||.:.......::.:
 Frog   339 NPARLKAVFQKYVPSFTGYSQQDAQEFLKFFMDRIHVEINRKGRKTPSILSDAKRPAALEHQDSL 403

  Fly   681 SASEKA---WLEFTKAKESMILHLFYGQMKSTVKCVACHKESATYESFSNLSLELPPN---SNVC 739
            |..|:|   |..:.:.::|.|:.||.||:||.:||.||...|.|:|.|.:|||.:|..   ....
 Frog   404 SDDERANQMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSPTFEVFCDLSLPIPKKGFAGGRV 468

  Fly   740 QLNQCMDMYFSGERIHGWN---CPSCKTKRDAIKKLDISKLPPVLVVHLKRFYADPSNSGSYMKK 801
            .|..|..::...|.::..|   |..|:.:..:.|||.|.:.|.:||:||.||    |.:...:||
 Frog   469 SLLDCFSLFTKEEELNSENAPICDRCRQRTRSTKKLTIQRFPRILVLHLNRF----STTRFSIKK 529

  Fly   802 QNY-LRFPLENLDMNPYIARAESRAVTPKTYQLYAVSNHYGTMEGGHYTAFCKSANYGKWFKFDD 865
            .:. :.|||..|.:..:   |..::..| ||.|||:.||.|::..|||||:|::.:  .|:.::|
 Frog   530 CSVSVDFPLHRLHLKEF---ASEKSGNP-TYNLYALCNHSGSVHYGHYTAYCRTQS--SWYAYND 588

  Fly   866 QVVSALDSSNVVSSAAYILFY-----TWLP 890
            ..||.::.|.|.|:..|:|||     .|.|
 Frog   589 SRVSPINESQVQSNEGYVLFYELDDTCWKP 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp8	NP_650948.2	USP8_dimer	2..113	CDD:286108
		RHOD	148..278	CDD:294087
		UCH	562..886	CDD:278850	116/348 (33%)
		Peptidase_C19R	564..887	CDD:239139	118/352 (34%)
usp21	XP_031746854.1	UCH	271..609	CDD:395355	116/347 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469048at33208
OrthoFinder	1	1.000	-	-		FOG0000821
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920