Protein Alignment Trm7-34 and FTSJ1

DIOPT Version :10

• Sequence 1: NP_650947.1
• Gene: Trm7-34 / 42508
• FlyBaseID: FBgn0038861
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001428126.1
• Gene: FTSJ1 / 24140
• HGNCID: 13254
• Length: 337
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 147/294 - (50%)
• Similarity: 199/294 - (67%)
• Gaps: 17/294 - (5%)

  Fly     1 MGRTSKDKRDIFYRLAKEQGWRARSAFKLLQADETFQLLEGLTRAVDLCAAPGSWSQVLAKRLYE 65
            ||||||||||::||||||.||||||||||||.|:.|||.:|:|||||||||||||||||::::
Human     1 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLSQKI-- 63

  Fly    66 PLPPEEREKVKIIAVDLQGMAPIEGVKQLRADISKESTAEAIIEFFGGEKAQIVVSDGAPDSTGM 130
                ..:....::|||||.|||:.||.|::.||::.|||:.||:.|.|..|.:||.|||||.||:
Human    64 ----GGQGSGHVVAVDLQAMAPLPGVVQIQGDITQLSTAKEIIQHFKGCPADLVVCDGAPDVTGL 124

  Fly   131 HDFDSYVQGELLLSALSISTFILEEGGSFVSKIYRADRTSRLYTQLKRFFKNVCVFKPSASRNSS 195
            ||.|.|:|.:|||:||:|:|.:|:.||.||:||:|....:.||:||:.||.:|...||.:|||||
Human   125 HDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRNSS 189

  Fly   196 IEAFVVAREFCLPDGYKPCNLTTEWHDQPESWVGRKKESPPVVQVPFVAYKGEL---DSDRTYDL 257
            ||||.|.:.:..|:|:.| :|:....|........:.:.|..:.||||.. |:|   ||||:|.|
Human   190 IEAFAVCQGYDPPEGFIP-DLSKPLLDHSYDPDFNQLDGPTRIIVPFVTC-GDLSSYDSDRSYPL 252

  Fly   258 ----GENYVYKEPVQQPLTAAYQD--ILQKTSQV 285
                |..|.|..|.|.|::..||:  .|::..|:
Human   253 DLEGGSEYKYTPPTQPPISPPYQEACTLKRKGQL 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trm7-34	NP_650947.1	RlmE	1..205	CDD:440062	119/203 (59%)
FTSJ1	NP_001428126.1	Required for binding to WDR6. /evidence=ECO:0000269|PubMed:32558197	221..240		5/19 (26%)