Protein Alignment Ice2 and ice2

DIOPT Version :10

• Sequence 1: NP_650946.3
• Gene: Ice2 / 42507
• FlyBaseID: FBgn0038860
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_012822356.2
• Gene: ice2 / 100380136
• XenbaseID: XB-GENE-5916977
• Length: 927
• Species: Xenopus tropicalis
• Alignment Length: 739
• Identity: 140/739 - (18%)
• Similarity: 257/739 - (34%)
• Gaps: 201/739 - (27%)

  Fly     4 MDSFAMDKDAKLYEGNALFRNQPSYKVFNK------------------------SFEHVDDALYT 44
            ||:....|:..:.|.|.:|...|......|                        |.|.|.:: |.
 Frog   317 MDTPLPKKELSMREKNKMFHEAPLDLFLKKNNNLLLEAVQLDKAEVLCQILSENSSERVHNS-YK 380

  Fly    45 LLNEVEPDVLRMELQETGDLFKSFNRNSALRDPRNNEVPPKPTRDLTTASSLYSFPNPLEQYSEL 109
            :..:.|.||..:|      .|.| .:|:..|||::   .|:.|:.::..:||         ..:|
 Frog   381 MDVDFETDVTELE------TFGS-TKNTVFRDPKS---APESTKSISVKTSL---------VKKL 426

  Fly   110 NLKQQAACMRVLLAWQCSQPVDEQDIVVWQATEKKRYNEQQRVQKYIHDHEQGRKEVIYAPMKSL 174
            .:::|.  :....:.:....:..|:..:  :|.::.:::.        |.|...|..:      |
 Frog   427 EMEKQV--IDTTRSGKIDGKISSQENFI--STTQELWSDS--------DDESSFKGFL------L 473

  Fly   175 VAVYRKWYELGVKKLQQTYPNDSYMTF----SGLPQLPQ-------------CRSLNAQTASIEQ 222
            |.| :.:.:..:.......|....:.|    ||.|...|             ||..|..|.:
 Frog   474 VEV-QDFQDESLNSYPTKIPEPRAVGFTANPSGKPDQSQSDSEDDKLVIDIDCRKNNKDTEN--- 534

  Fly   223 VELERIVGRVRLLPEVEVRHEALRTLRLRLDRYATRETRAPVQLLREEDKELELEAGNVFVLPLD 287
                     ..|:|:........          .|:|:.:   |.|:..|.|..|..     |:.
 Frog   535 ---------STLMPKSPTSTPFT----------CTKESES---LPRKPTKALSKEFD-----PVG 572

  Fly   288 SLL----MLLTTGSYIDLPTEMFLSLRESPNSKHKC-MEFQSPFPPRNCGWHTNSLILKLAYGAY 347
            .:|    .||.:|:     |:.......:|:|.|.. .|..:|..|        |:.|
 Frog   573 QILKMQKQLLKSGT-----TKTQEQSAVNPDSGHAAQQEVITPLNP--------SVSL------- 617

  Fly   348 ISQPGQAKWLDFNINGAVKEVPDEPACD--KSSIDLQMVYKPRAIDQQPSDIEDGNCNSALVSWT 410
                         ::.|....|...||:  ||.:...::   .|::.:...|.....||....::
 Frog   618 -------------VSDADNNSPMNQACNVKKSLLSKDLL---AALEDETEYIAPTEGNSTYKLFS 666

  Fly   411 LRCKGEGDDCNDFQIFSTLSI------PAVKDSSGKEPLGCHFIKLENKPDC-GCEIMSKYELIS 468
            |         :|..:....|:      ....|.:.::.:..:.:...|...| |.||:::.|:..
 Frog   667 L---------DDMLLLIRSSVHKAYTYKRAHDKTTRKQVPVYVLTKINYQWCYGVEILTESEICK 722

  Fly   469 AWVQLKLMRAE----MGHCTRISLRDFEPMLEEKLTLISLEQQLHDYYNTSMP-QLLSNLCEFLK 528
            .|.: .|:.:.    :||....:.:.|  ||||    |:.| :|:|..:...| ..|:.|...||
 Frog   723 LWTE-SLLHSNSVLYIGHIDAFTSKFF--MLEE----ITCE-RLNDMISNLKPINSLNILHHILK 779

  Fly   529 LLDTVPAGDYLLRYSPKYKDKFLLCIV--TKEATPQSFQLHQLLTESIPSDQAFLTQSSYLPISP 591
            .:..:..|.|||.::   .....:|:.  |.|:...|:.||. ...|:|.:.:.|. ..::.:..
 Frog   780 WVSDLQDGSYLLSHT---SGDSSVCLYKSTSESCRGSYNLHD-AHASLPKNLSTLC-VPWVAVDS 839

  Fly   592 TLCGRLHEELHLLPCAFPAKA----------NGRSVQRRKVVVPIPEPSRQAPVRRQRLKKWSEA 646
            .|....|......||.||...          ..:..|..|..:..|..:.:.|...::.||.::.
 Frog   840 NLLLPYHIHNGRPPCTFPPPPVRKKEKPQVDEQKESQNNKETLAKPATNSEGPEPAKKKKKKNKG 904

  Fly   647 QTREFRRRCKVDQKKRARARKTAA 670
              :...|:.|:..||||...:.||
 Frog   905 --KRAARQQKLKDKKRACKAEAAA 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ice2	NP_650946.3	NARG2_C	395..610	CDD:463121	49/228 (21%)
ice2	XP_012822356.2	NARG2_C	651..851	CDD:463121	46/221 (21%)