Protein Alignment slmb and btrc

DIOPT Version :10

• Sequence 1: NP_001262802.1
• Gene: slmb / 42504
• FlyBaseID: FBgn0283468
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_012822030.1
• Gene: btrc / 549140
• XenbaseID: XB-GENE-486122
• Length: 610
• Species: Xenopus tropicalis
• Alignment Length: 504
• Identity: 397/504 - (78%)
• Similarity: 442/504 - (87%)
• Gaps: 9/504 - (1%)

  Fly     4 METDKIMDETN-SNAQAFTTTMLYDPVRKKDSSPTYQTERELCFQYFTQWSESGQVDFVEHLLSR 67
            |:|:..:.:|. :|.   |::|:....||  .|..|:.|:|||.:||.||||..||:|||||:||
 Frog   105 MKTESCVVKTKLANG---TSSMIVPKQRK--LSANYEKEKELCVKYFEQWSECDQVEFVEHLISR 164

  Fly    68 MCHYQHGQINAYLKPMLQRDFITLLPIKGLDHIAENILSYLDAESLKSSELVCKEWLRVISEGML 132
            |||||||.||.||||||||||||.||.:|||||||||||||||.||.|:|||||||.||.|:|||
 Frog   165 MCHYQHGHINTYLKPMLQRDFITALPARGLDHIAENILSYLDARSLCSAELVCKEWYRVTSDGML 229

  Fly   133 WKKLIERKVRTDSLWRGLAERRNWMQYLFKPRP--GQTQRPHSFHRELFPKIMNDIDSIENNWRT 195
            |||||||.||||||||||||||.|.|||||.:|  |:|. |:||:|.|:|||:.||::||:|||.
 Frog   230 WKKLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGKTP-PNSFYRALYPKIIQDIETIESNWRC 293

  Fly   196 GRHMLRRINCRSENSKGVYCLQYDDGKIVSGLRDNTIKIWDRTDLQCVKTLMGHTGSVLCLQYDD 260
            |||.|:||:||||.|||||||||||.|||||||||||||||:..|:|.:.||||||||||||||:
 Frog   294 GRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRVLMGHTGSVLCLQYDE 358

  Fly   261 KVIISGSSDSTVRVWDVNTGEMVNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITL 325
            :|||:|||||||||||||||||:||||||||||||||||||||||||||||||||||.|.::|||
 Frog   359 RVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASATDITL 423

  Fly   326 RRVLVGHRAAVNVVDFDEKYIVSASGDRTIKVWSTSSCEFVRTLNGHKRGIACLQYRDRLVVSGS 390
            |||||||||||||||||:|||||||||||||||:||:||||||||||||||||||||||||||||
 Frog   424 RRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGS 488

  Fly   391 SDNSIRLWDIECGACLRVLEGHEELVRCIRFDTKRIVSGAYDGKIKVWDLVAALDPRAASNTLCL 455
            |||:||||||||||||||||||||||||||||.|||||||||||||||||||||||||.:.||||
 Frog   489 SDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCL 553

  Fly   456 NTLVEHTGRVFRLQFDEFQIVSSSHDDTILIWDFLNFTPNENKTGRTPS 504
            .|||||:|||||||||||||||||||||||||||||......::.|:||
 Frog   554 RTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAHAESTRSPS 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slmb	NP_001262802.1	Beta-TrCP_D	47..85	CDD:463465	29/37 (78%)
		F-box_FBXW1B	85..135	CDD:438954	40/49 (82%)
		WD40	210..488	CDD:238121	251/277 (91%)
		WD40 repeat	213..248	CDD:293791	26/34 (76%)
		WD40 repeat	254..288	CDD:293791	29/33 (88%)
		WD40 repeat	293..330	CDD:293791	32/36 (89%)
		WD40 repeat	337..370	CDD:293791	29/32 (91%)
		WD40 repeat	376..410	CDD:293791	32/33 (97%)
		WD40 repeat	416..459	CDD:293791	37/42 (88%)
		WD40 repeat	465..487	CDD:293791	21/21 (100%)
btrc	XP_012822030.1	Beta-TrCP_D	144..182	CDD:463465	29/37 (78%)
		F-box_FBXW1A	180..239	CDD:438953	48/58 (83%)
		WD40	308..586	CDD:238121	251/277 (91%)
		WD40 repeat	311..346	CDD:293791	26/34 (76%)
		WD40 repeat	352..386	CDD:293791	29/33 (88%)
		WD40 repeat	391..428	CDD:293791	32/36 (89%)
		WD40 repeat	435..468	CDD:293791	29/32 (91%)
		WD40 repeat	474..508	CDD:293791	32/33 (97%)
		WD40 repeat	514..557	CDD:293791	37/42 (88%)
		WD40 repeat	563..585	CDD:293791	21/21 (100%)