Protein Alignment slmb and LOC101734025

DIOPT Version :10

• Sequence 1: NP_001262802.1
• Gene: slmb / 42504
• FlyBaseID: FBgn0283468
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_004913374.2
• Gene: LOC101734025 / 101734025
• XenbaseID: XB-GENE-29087467
• Length: 443
• Species: Xenopus tropicalis
• Alignment Length: 457
• Identity: 121/457 - (26%)
• Similarity: 185/457 - (40%)
• Gaps: 112/457 - (24%)

  Fly    86 RDFITLLPIKGLDHIAENILSYLDAESLKSSELVCKEWLRVISEGMLWKKLIERKVRTDSLWRGL 150
            :|..:.||    |.:|..|||||||:.:......|:.|..:..:..||    :.|.:.|    |:
 Frog     7 QDCTSWLP----DELALRILSYLDAKDILQVAQTCQRWRELAEDEGLW----QGKCKAD----GI 59

  Fly   151 AERRNWMQYLFKPRPGQTQRPHSFHRELFP---KIMNDIDSIENNWRTGRHMLRRINCRSENSKG 212
            .|            |.|..|..:......|   ...|.: .::.|||.||.....:|..|||.:
 Frog    60 EE------------PPQVTRSRAKGSGSGPWKSAYTNQL-RVDTNWRRGRFRRITLNLISENRR- 110

  Fly   213 VYCLQYDDGKIVSGLRDNTIKIWDRTDLQCVKTLMGHTGSVLCLQYDDKVIISGSSDSTVRVWDV 277
            :|.:.::..::|.......||:|.....:|::||:|...||..:|..|.:|:||..|.||:||:.
 Frog   111 LYWMAFNGKELVCTTHKEIIKVWSAVTGECLRTLVGDRASVTAVQMRDHMIVSGYEDGTVKVWNA 175

  Fly   278 NTGEMVNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVVDFD 342
            .:||.::|                                           |.||.|.::.|...
 Frog   176 ESGECIHT-------------------------------------------LGGHTAYIHHVHLH 197

  Fly   343 EKYIVSASGDRTIKVWSTSSCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNSIRLWDIECGACLR 407
            |:...|.|.||||:||...:.:.:.||.||:..:..:.|..|.:||....|.:::||.|...||.
 Frog   198 EQRAASCSTDRTIRVWDIEAGQCLHTLLGHEASVMWVWYNGRRLVSEDFSNVVKMWDPETETCLL 262

  Fly   408 VLEGHEELVRCIRFDTKRIVSGAY-DGKIKVWD------LVAALDPRAASNTLCLNTL-VEHTGR 464
            .:..|......::||.|.|||..| ||.|.|||      .:...:|.....||..:.| |.::||
 Frog   263 SVCLHSGAFTPVQFDGKHIVSLLYSDGTIGVWDGETLQRTITGNEPYTIVMTLKNSILGVVNSGR 327

  Fly   465 VF---------RLQF----DEFQIVSSS----------HDDT--ILIWD-----FLN--FTPNEN 497
            ..         ||..    |.|.:.::|          ..||  |.:||     ||.  |.|...
 Frog   328 AAEIWNVETGQRLNLLQDPDGFDLRANSLALRGDFLIGRTDTGRITLWDWRTGQFLRNLFVPKRE 392

  Fly   498 KT 499
            ::
 Frog   393 ES 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slmb	NP_001262802.1	Beta-TrCP_D	47..85	CDD:463465
		F-box_FBXW1B	85..135	CDD:438954	16/48 (33%)
		WD40	210..488	CDD:238121	81/310 (26%)
		WD40 repeat	213..248	CDD:293791	8/34 (24%)
		WD40 repeat	254..288	CDD:293791	13/33 (39%)
		WD40 repeat	293..330	CDD:293791	0/36 (0%)
		WD40 repeat	337..370	CDD:293791	11/32 (34%)
		WD40 repeat	376..410	CDD:293791	10/33 (30%)
		WD40 repeat	416..459	CDD:293791	17/50 (34%)
		WD40 repeat	465..487	CDD:293791	8/46 (17%)
LOC101734025	XP_004913374.2	F-box_SF	1..51	CDD:459239	16/51 (31%)
		WD40	38..386	CDD:441893	106/412 (26%)
		WD40 repeat	108..145	CDD:293791	8/37 (22%)
		WD40 repeat	192..226	CDD:293791	12/33 (36%)
		WD40 repeat	231..262	CDD:293791	9/30 (30%)
		WD40 repeat	263..304	CDD:293791	14/40 (35%)