DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppan and SPAC1B9.03c

DIOPT Version :9

Sequence 1:	NP_476979.1	Gene:	ppan / 42502	FlyBaseID:	FBgn0010770	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_593755.2	Gene:	SPAC1B9.03c / 2542610	PomBaseID:	SPAC1B9.03c	Length:	389	Species:	Schizosaccharomyces pombe

Alignment Length:	388	Identity:	137/388 - (35%)
Similarity:	218/388 - (56%)	Gaps:	38/388 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MG--GKKKVHPKTRTAAFKASEPSEIVEAPHSFVIHRGLA--CPYITDLTLDFRRIMEPFTASNL 61
            ||  |||:|..:|...|    :|.:....|.|.||..|.:  ...::.||.|.|.:|||.||..|
pombe     1 MGGIGKKRVKKRTHLKA----DPIQEAAIPKSMVIRSGASEVGRSLSLLTRDLRHMMEPHTAIRL 61

  Fly    62 REKRMNRIKDFVSLSSFFHVSHMGIFNKASTQLSFKVVRLPRGPSLTFKVHQFTLARDVISLSKK 126
            :|::.|:|||:::::....|:|:.:.::.....:.:::|.||||||.|::|::.|.:||..|.|.
pombe    62 KERKANKIKDYLTMAGPLGVTHLLVLSRTDNNANLRIIRAPRGPSLHFRIHEYMLNKDVRRLQKN 126

  Fly   127 QMIDNDHFKHAPLVIMNNF----SGDGKHLKLMATTFQNMFPSINLATVNIGTIRRCVLFSYNPD 187
            .......|...||::||:|    |.|..|..|:.||||||||.|::...||.:::|.:|.: ..|
pombe   127 PKSPTTEFLTPPLLVMNHFNQNSSKDSPHEALLTTTFQNMFPPISVQHTNINSVKRVLLLN-RRD 190

  Fly   188 TKLVEMRHYSVQVVPVGLKRAVQKIVKG-----TVPNLGKCNEVVDFVTK----DGYASESEAED 243
            ...:::||:.:...|||:.|.::.::||     .:|:|....::.|:|..    .|.||:||.|:
pombe   191 DGYIDLRHFIISTKPVGISRPIRHLLKGEKKDSDIPDLHNVRDISDYVLHGDGISGAASDSEIEE 255

  Fly   244 DEQSHVVLAQTLKSKGN-------LEDKKSSIKLHEIGPRLTMQLIKIEEGLLTGEVLYHDHVVK 301
            |....:......|::.|       |:.|:.:|||.|||||:|::||||.|..:.|:||||.||.|
pombe   256 DATVEIDRPVPTKTEENLLSASQLLKPKQQAIKLIEIGPRMTLELIKITEDAMGGKVLYHSHVHK 320

  Fly   302 TEDEKETLRKLVEKKRKQKEQRKKEQAEN---RARNLKLKKDEKWAAKRAAEGRTDSDPEDDA 361
            :::|.:......|:.|..||:|||||.||   :..|.|.:||:|      .||.|.|:..||:
pombe   321 SKEEIKQQDNFHEQSRALKEKRKKEQDENVRRKRENKKRRKDQK------KEGITSSNKNDDS 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppan	NP_476979.1	Brix	31..212	CDD:214879	64/186 (34%)
ppan	NP_476979.1	Brix	<215..295	CDD:294606	32/95 (34%)
SPAC1B9.03c	NP_593755.2	Brix	42..204	CDD:282306	57/162 (35%)
SPAC1B9.03c	NP_593755.2	Brix	<283..350	CDD:294606	34/66 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	166	1.000	Domainoid score	I935
eggNOG	1	0.900	-	-		E1_KOG2963
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5690
Inparanoid	1	1.050	222	1.000	Inparanoid score	I897
OMA	1	1.010	-	-		QHG53510
OrthoFinder	1	1.000	-	-		FOG0004323
OrthoInspector	1	1.000	-	-		oto100839
orthoMCL	1	0.900	-	-		OOG6_101976
Panther	1	1.100	-	-	LDO	PTHR12661
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1766
SonicParanoid	1	1.000	-	-		X3054
TreeFam	1	0.960	-	-
	14	13.860