Protein Alignment Rab11 and RAB9A

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Alignment Length: 208
• Identity: 76/208 - (36%)
• Similarity: 124/208 - (59%)
• Gaps: 18/208 - (8%)

  Fly    11 LFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAGQERYRA 75
            ||||:|:||.|||||:|::|:..|:|:.:...||||||..:.:||||..:..||||||||||:|:
Human     7 LFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRS 71

  Fly    76 ITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHAD----QNIVIMLVGNKSDLRHLRSVPT 136
            :.:.:|||:...||.:.:....:::|:..|.:|...:||    ::...:::|||.|:.. |.|.|
Human    72 LRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISE-RQVST 135

  Fly   137 DEAKLFAERNG-LSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDPPEGDVIRPSNVEPIDV 200
            :||:.:...|| ..:.||||.|:|||..||:.   .:.|:::.:...|    .:|:...|. :..
Human   136 EEAQAWCRDNGDYPYFETSAKDATNVAAAFEE---AVRRVLATEDRSD----HLIQTDTVN-LHR 192

  Fly   201 KPTVTADVRKQCC 213
            ||..::    .||
Human   193 KPKPSS----SCC 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	68/166 (41%)
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	68/168 (40%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		3/10 (30%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		6/13 (46%)