Protein Alignment Rab11 and RAB2B

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_116235.2
• Gene: RAB2B / 84932
• HGNCID: 20246
• Length: 216
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 102/214 - (47%)
• Similarity: 130/214 - (60%)
• Gaps: 8/214 - (3%)

  Fly     8 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAGQER 72
            |.||||.::|||:|||||.||.:||...|......||||||..|.:.:|||.||.|||||||||.
Human     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQES 67

  Fly    73 YRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRHLRSVPTD 137
            :|:||.:|||||.||||||||.:..|:.::..||.:.|.|:..|:||||:||||||...|.|..:
Human    68 FRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKRE 132

  Fly   138 EAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQK--QIRDPPEGDVIRPSNVEPIDV 200
            |.:.||..:||.|:||||..:.|||.||.|...||||.:.|.  .:.:...|..|.|.......|
Human   133 EGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSV 197

  Fly   201 KPTV----TADV--RKQCC 213
            .|:.    :.|:  ...||
Human   198 GPSASQRNSRDIGSNSGCC 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	89/163 (55%)
RAB2B	NP_116235.2	PLN03108	1..216	CDD:178655	100/212 (47%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		5/8 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..216		4/26 (15%)