DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab11 and Rab11b

DIOPT Version :9

Sequence 1:	NP_477170.1	Gene:	Rab11 / 42501	FlyBaseID:	FBgn0015790	Length:	214	Species:	Drosophila melanogaster
Sequence 2:	NP_116006.1	Gene:	Rab11b / 79434	RGDID:	68369	Length:	218	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	183/218 - (83%)
Similarity:	192/218 - (88%)	Gaps:	6/218 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGAREDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIW 65
            ||.|:||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||
  Rat     1 MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIW 65

  Fly    66 DTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRH 130
            |||||||||||||||||||||||||||||||||||||||||:|||||||.|||||||||||||||
  Rat    66 DTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRH 130

  Fly   131 LRSVPTDEAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDPPEGDVIRPSNV 195
            ||:||||||:.|||:|.|||||||||||||||.||:|||||||||||||||.|....|....:||
  Rat   131 LRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNV 195

  Fly   196 EPIDVKPTVTADVRK----QCCQ 214
            ..|.|.|  |.|.:|    ||||
  Rat   196 VDISVPP--TTDGQKPNKLQCCQ 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	153/163 (94%)
Rab11b	NP_116006.1	Rab11_like	9..173	CDD:206660	153/163 (94%)
		Effector region. /evidence=ECO:0000255	40..48		7/7 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	184..218		13/35 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	302	1.000	Domainoid score	I1354
eggNOG	1	0.900	-	-		E2759_KOG0087
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	363	1.000	Inparanoid score	I2110
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133775at2759
OrthoFinder	1	1.000	-	-		FOG0000259
OrthoInspector	1	1.000	-	-		otm45116
orthoMCL	1	0.900	-	-		OOG6_100582
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X277
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.730